DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG13325 and oac-50

DIOPT Version :9

Sequence 1:	NP_001286373.1	Gene:	CG13325 / 36437	FlyBaseID:	FBgn0033792	Length:	697	Species:	Drosophila melanogaster
Sequence 2:	NP_001309487.1	Gene:	oac-50 / 179284	WormBaseID:	WBGene00020864	Length:	731	Species:	Caenorhabditis elegans

Alignment Length:	759	Identity:	159/759 - (20%)
Similarity:	301/759 - (39%)	Gaps:	143/759 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 VIVFLLC----GFVI----ISAGNPNSDDVLPQ--FRNVRQLRSLGIE--------FTEYFRNIS 51
            ||:|.:.    |.|:    |.|...||...:.|  :||..::||..:.        ...:|:|::
Worm     9 VIIFWILLQIEGVVVNDSRIQALLLNSSFSIEQLDYRNKNEIRSGEVATPDLCKTLMKRWFQNLN 73

  Fly    52 TQDLGGLESQFSSEDDLLCLNDMKALMTGLGSAEYWALKMIDAWGSIPS-GLLAGNSYDLGNFDE 115
            :...|..:    :.||  ||:               ||..:||:...|: |  :.|.|| |:|.:
Worm    74 SLKNGTCK----NSDD--CLD---------------ALDQLDAFARYPAPG--SPNIYD-GSFRK 114

  Fly   116 CLNIRKEIGQERTIQGKYCFLSVSPAKILGIETSIGSF-----RTA--TCFPASCSA---INMNA 170
            |.::.::.|..|    |||:|..:..| :.......|.     |||  .|.|..|..   .:|..
Worm   115 CNDLNEKGGHRR----KYCYLIQADEK-MNCREEYHSILFKPNRTAFGFCGPEICHGKDYASMFG 174

  Fly   171 FVDQLMMKLLNVSVPSSAMRISEGSCQTSDSEPWDALTIFMIVILSLMSFIVALSTLWDYF---- 231
            .:::....|::..|.::       .|...|. |......|....|.::..:|..|:|:||.
Worm   175 SMEKTFHFLMDRPVCAA-------FCTVRDI-PKKLQFYFFTAFLIMLGSVVFFSSLYDYVRDTR 231

  Fly   232 --LVKDQDQL--PAIVKICSARSNSRALFRVVESHSNPNVIDCLHGIRCMSLIWVITCHQYSVTL 292
              |..:.:::  ..|:...|..||...:|:    ...|:.|..|..||.::..||:..:
Worm   232 YRLSSESEKVFGQRIILSFSLWSNIEFIFQ----DKRPDYIRSLDCIRAITFTWVVGQN------ 286

  Fly   293 ISPHINLFRAATWVEK---PFASFILHGFISVDSFLVIGGLLVALIPLR---LMDKTKGKLNVPM 351
            :..|:..:.....|:.   ..||..:...:.:.::|.:.||.|:...|:   .:|..|......:
Worm   287 VVGHLGFYDDKIRVDPSKISLASSAMSSLLPIYTYLFMSGLTVSYTFLKGKPSLDVLKQPFTWLI 351

  Fly   352 MYLHRLIRIAPLLAMAIVVHMKLMPLISSGPL-FVGGYIGNSACKAGWYW-TLLFVNNY--TDAK 412
            .:.||.||:...| |..:...........||. .:.||...:......|| .::.::|:  .|..
Worm   352 FFFHRWIRLTSAL-MVFIGFFDAYGKYIQGPYDALTGYSMVTQTDLCTYWMDIIHISNFVAVDEM 415

  Fly   413 CLAQSWYLSLDMQLYIISPILLISLYKWGKKAAAGIFILIILLSACLFATMMVNGYSMMITAASP 477
            |...:|:|::|.|..|.:|..|::.:   .....|..:.||       |:::.:|.::.....:
Worm   416 CYLPAWHLAVDFQFTIFAPFFLLAFH---YSTVLGTILAII-------ASLIGSGLTVFFFLQN- 469

  Fly   478 EAMRDGYYATHTH---------ATPW------LIGFLFGYFLHLNRGKKFQLSWVSVWSGWILCL 527
            ..:...:...|.|         :.||      ::|.:.|..|..:.|.|..:..|:....||:..
Worm   470 TILNSAFTGDHVHDDKLVEIILSKPWNQMAPYMMGMIAGCILGKHSGSKRIIHPVASSIIWIIIT 534

  Fly   528 AM-IFTSIFALYPPSKWSDPDASTLAESFYYTLTRVGWALALCWVIFACVQGYGGLANSFLASPL 591
            .: :...||..:        ..|.|.::.....||..|::.|.|:|.:......|....:|..|.
Worm   535 VLGLVALIFGHF--------GTSQLEKALTNVSTRAVWSICLMWIIISTELKSAGPIGHYLEHPF 591

  Fly   592 WQPLSRLSYSVFIWH----MFFMEMNARSTRTSTYFSDYGMMLNFWSTLG---FTLLFSYAMHLL 649
            |:|..:||:..||.|    .|...:...:.:.::::.:|     |..|:.   ::...::.:.::
Worm   592 WRPFGKLSFCAFIVHHMLLYFLFNIQEEAPKYTSFWHEY-----FHYTIPIVIYSYFLAFFLSVV 651

  Fly   650 IEAPIGGLD-IFLRPKGKISPTEKQTSHIDDKEPRDPENLLEPT 692
            :|.||..:| :.:.....:|..||:|...:|...:|..|..:.|
Worm   652 VEIPILRIDRLIIDQFVPVSKIEKKTDVEEDDSFKDTSNRSDNT 695

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG13325	NP_001286373.1	NRF	85..198	CDD:214781	30/123 (24%)
		Acyl_transf_3	268..648	CDD:280013	80/412 (19%)
		OafA	299..654	CDD:224748	74/387 (19%)
oac-50	NP_001309487.1	NRF	86..195	CDD:214781	32/138 (23%)
oac-50	NP_001309487.1	Acyl_transf_3	268..646	CDD:376607	80/408 (20%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	204	1.000	Domainoid score	I1719
eggNOG	1	0.900	-	-		E1_KOG3700
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	238	1.000	Inparanoid score	I2120
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1171418at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100705
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X299
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	8	7.730