DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG13325 and oac-55

DIOPT Version :9

Sequence 1:	NP_001286373.1	Gene:	CG13325 / 36437	FlyBaseID:	FBgn0033792	Length:	697	Species:	Drosophila melanogaster
Sequence 2:	NP_001317839.1	Gene:	oac-55 / 178792	WormBaseID:	WBGene00021479	Length:	742	Species:	Caenorhabditis elegans

Alignment Length:	817	Identity:	194/817 - (23%)
Similarity:	327/817 - (40%)	Gaps:	212/817 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 IVFLLCGFVIISAGNPNSDDVLPQFRNVRQLRSLG------IEFTEYFRNISTQDL---GGLESQ 61
            :||::...:..|:|        .:|...:.:..||      ||..|......|.||   .|:.|.
Worm    10 LVFIIFANLQCSSG--------IEFDPHKAMELLGELIAHPIEVMEQLEKYKTSDLIAALGIHSN 66

  Fly    62 FSSEDDLLCLNDMKALMTG-LGSAEY--------------------WALKMIDAWGSIPSGLLAG 105
            .:......|..::..|..| :.:|.|                    :.:.|:||.|.:.||::.|
Worm    67 ANYSISQECHEELSFLGYGVIDAARYARHHSTAAVPASMTDQERKDYLIPMMDAAGKLGSGIVRG 131

  Fly   106 NSYDLGNFDECLNIRK-EIGQERTIQGKYCFLSVSPAKILGIETSIGSFRTA---------TCFP 160
            :....|.|.||.:|:. .....||:||.|    .|...:..::....||.::         .|.|
Worm   132 HILSTGAFSECKSIQMFSSSLNRTVQGDY----YSSRILFDMKMRPNSFNSSCNLPQIGVDLCLP 192

  Fly   161 ASCSAINMNAFVDQLM-----------MKLLNVSVPSSAMRISEGSCQTSDSEPWDALTIFMIVI 214
            .||...::..:..:.:           ::.:|..||.    ||.|:        |        ::
Worm   193 WSCRNEDLTGYFREALGPSKALSPVCSVRNVNQRVPV----ISLGT--------W--------IV 237

  Fly   215 LSLMSFIVAL------STLWDYFLVKDQDQLPAIV--KICSARS---NSRALFRVVESHSNPNVI 268
            |.::|.||.|      |.::..|.:.|:.:.....  |:.||.|   |.:.:|.....|....|.
Worm   238 LLILSLIVGLCILSGFSDIFQKFQLNDKTRKEEGFGWKLFSAFSFHRNLKEIFNTKNCHKEGQVT 302

  Fly   269 DCLHGIRCMSLIWVI--TCHQYSVTLISPHINL--FRAATWVEKPFASFILHGFISVDSFLVIGG 329
            . |:.||.:|..|||  .|.:.:..:|:..|:|  |...|:.    .:.|.:.:.|||:|..|..
Worm   303 S-LNCIRVISTFWVIFGHCSEITFMVITNPIDLYDFTKDTYT----GTLISNAYFSVDTFFFISA 362

  Fly   330 LLVALIPLRLMDKTKGKLNVP----MMYLHRLIRIAP-----LLAMAIVVHMKLMPLISSGPLFV 385
            .|::.:..:.::|....|..|    |.|:||:.|::|     :|....|....::.:    |.|:
Worm   363 FLLSFLWFKQLEKQWNALLSPGGWLMFYVHRIARLSPVYYVTILFFTFVFTRSMVDM----PAFM 423

  Fly   386 GGYIGNSACKAGWYWTLLFVNNYTDAK--CLAQSWYLSLDMQLYIISPILLISLYKWGKKAAAGI 448
            ...:.:..|:..::..||::.|....|  |...||||:.|:|:||:||::|:|.      ...|.
Worm   424 TPAVVDDTCQNSYWVNLLYIQNIVGPKDICYFISWYLATDLQIYIMSPLILLSF------GLGGA 482

  Fly   449 FILIILLSACLFATMMVNGYSMMITAASPEAMRDG-----------YYATHTHATP------WLI 496
            .:.:::.:|...|:...|.|.|:.....|.....|           .||...:..|      :::
Worm   483 VVGLLISTAAFLASTAFNAYQMIFWHFPPSDYNYGPKDPLYDPSKRRYAAWNYHNPLIRCQIYIM 547

  Fly   497 GFLFGYFLHLNRGKKFQLS-WVS--VWSGWILCL---AMIFTSIFA-------LYPPSKWSDPDA 548
            |.:.|||  :.|..|..:: ||.  :|     ||   :|||..:..       |:.|
Worm   548 GMVLGYF--MRRIPKININPWVDRIMW-----CLSLGSMIFVIVIMEDYTSGHLWSP-------- 597

  Fly   549 STLAESFYYTLTRVGWALALCWVIFACVQGY--GGLANSFLASPLWQPLSRLSYSVFIWHM---- 607
              |..:.|...:||.|.|||.|::   :..|  .||.|.|::.|:|.||:|||:..::.|:
Worm   598 --LQTALYSCFSRVVWGLALSWIV---ISTYYRKGLINKFMSLPVWTPLARLSFCAYLVHLMVAA 657

  Fly   608 FFMEMNARSTRTST--YF---------SDYGMMLNFWSTLGFTLLFSYAMHLLIEAPIGGLDIFL 661
            :|...|......||  ||         |...::..||||: |.|.|:....||    :||
Worm   658 YFFGRNHSELYFSTLPYFVLVIAIPVISCSFLVAIFWSTM-FELPFAKVEALL----LGG----- 712

  Fly   662 RPKGKISPTEKQTSHID-DKEPRD-PENLLEPTTSTV 696
                     ..::|..| .|.|.| |||..|....::
Worm   713 ---------GSRSSAPDIPKTPIDFPENNFEKNVESI 740

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG13325	NP_001286373.1	NRF	85..198	CDD:214781	31/153 (20%)
		Acyl_transf_3	268..648	CDD:280013	114/441 (26%)
		OafA	299..654	CDD:224748	106/414 (26%)
oac-55	NP_001317839.1	NRF	111..220	CDD:214781	24/112 (21%)
oac-55	NP_001317839.1	OafA	299..690	CDD:224748	108/425 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3700
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1171418at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm14368
orthoMCL	1	0.900	-	-		OOG6_100705
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	6	5.680