DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG13325 and oac-31

DIOPT Version :9

Sequence 1:	NP_001286373.1	Gene:	CG13325 / 36437	FlyBaseID:	FBgn0033792	Length:	697	Species:	Drosophila melanogaster
Sequence 2:	NP_503441.2	Gene:	oac-31 / 178643	WormBaseID:	WBGene00018707	Length:	705	Species:	Caenorhabditis elegans

Alignment Length:	744	Identity:	199/744 - (26%)
Similarity:	328/744 - (44%)	Gaps:	129/744 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 IVFLLCGFVI-----ISAGNPNSDDVLPQFRNVRQLRSLGIEFTEYFRNISTQDLGGLESQFSSE 65
            ::||:....:     ||..|.|..|:.    :.:.|..|    :|...|.:...|..||...:..
Worm     4 LLFLVLSLFLPFSHCISTMNSNWKDIF----DPKPLHDL----SEKCLNDTDTWLKSLEIFSTVS 60

  Fly    66 DDLLCLNDMKALMTGLGSAEYWALKMIDAWGSIPS-GLLAGNS-YDLGNFDECLNIRKEIGQERT 128
            .:.|.||:.....:.:.....:|:|.:||:|..|: |||...: || |::.||    ..|..||
Worm    61 VECLTLNNCTTQESKILDENLYAVKQLDAFGEFPTPGLLELRTLYD-GSYQEC----DRIDGER- 119

  Fly   129 IQGKYCFLSVSPAKILGIET----SIGSFRTATCFPASCSAINMNAFVDQLMMKLLNVSVPSSAM 189
            .:..||:|.::..|.:....    |..:.|.|.|.|.|||..:|....:||.      ..|.:|
Worm   120 YKTNYCYLILNFGKNISCSAPSVYSNVTLRMAVCLPDSCSHQDMINIFNQLS------PYPFTA- 177

  Fly   190 RISEGSCQTSDSE---PWDALTIFMIVILSLMSFIVALSTLWDYFL----VKDQDQLPAIVKICS 247
              .:..|..:..|   |:...|:|:.:::::..|...|..:.|..|    :|:::....|:...|
Worm   178 --CDAYCVKNTVEKDVPFWGFTVFLTIVIAVAIFATLLDYVQDAVLGLSNLKEKNIFIKIILTFS 240

  Fly   248 ARSNSRALFRVVESHSNPNVIDCLHGIRCMSLIWVITCHQYSVTLISPHINLFRAATWVEKPFAS 312
            ..:|:..:..|.|  ..|..|..|..||.:|:.||||.|.:        |.:.:|.|.  ||...
Worm   241 LWTNAELILSVKE--HKPGFIKSLDCIRGLSIFWVITGHSF--------IYMTQADTM--KPVME 293

  Fly   313 F--------ILHGFISVDSFLVIGGLLVALIPLRLMDKTKGKLNVPM---------MYLHRLIRI 360
            |        |::..:|||||..:.|::||.:..::      |.|:.|         .|:||.:|:
Worm   294 FQNQFWNHLIINAPVSVDSFFALSGIVVAYLFFKM------KPNIKMAASPVTWILFYVHRYLRL 352

  Fly   361 APLLAMAIVVHMKLMPLISSGPLFVGGYIGN------SACKAGWYWTLLFVNNYTDAK------C 413
            .|.:.:.|.......|.: .|| |...: .|      .|||..|:..||::||:.:::      |
Worm   353 TPTVMIFIGFFTVYFPYV-QGP-FAASF-SNVQFPQVEACKDYWWHNLLYINNFDNSQHRERNTC 414

  Fly   414 LAQSWYLSLDMQLYIISPILLISLYKWGKKAAAGIFILIILLSACLFATMMVNGYSMMITAASPE 478
            .|.:|||::|.||||::||:||:|:   ...|.|..|::......:.||.::  :.:....|.|.
Worm   415 YAITWYLAVDTQLYILAPIVLIALF---FSFAVGTAIIVAGCVGSIIATYIL--FDLYDVPADPL 474

  Fly   479 AMRD-------GYYATHTHATPWLIGFLFGYFLHLNRGKKFQLSWVSVWSGWILCLAMIFTSIFA 536
            ...|       ||........|:|:|.|.||.|.....::.:|:|......||:...:....||:
Worm   475 GNGDHRYFFGIGYSKPWIRCPPYLVGLLTGYLLATYGTRRIRLNWAVSIGVWIVAFVVAGFCIFS 539

  Fly   537 LYPPSK---WSDPDASTLAESFYYTLTRVGWALALCWVIFACVQGYGGLANSFLASPLWQPLSRL 598
            .|...|   |     ||.:.:.::...|:||.:.:|||:.|...|:||..::|::.|:|||..||
Worm   540 TYDYDKGEQW-----STFSRATFFNFHRLGWGVFVCWVVGANHMGWGGPIDTFMSHPIWQPFGRL 599

  Fly   599 SYSVFIWH----MFFMEMNARSTRTST-----YFSDYGMMLN-----FWSTLGFTLLFSYAMHLL 649
            ||..:|.|    .|::.:......||.     |.|....:|:     |||.| |.:.......:|
Worm   600 SYCAYIVHWMVLYFYLNVGGALHYTSAWHVFLYISIPATVLSFVFAFFWSCL-FEMPILKLEKML 663

  Fly   650 IEAPIGGLDIFLRPKGKISPTEKQTSHID 678
            ||:.:|...:   |..|.|..||.|...:
Worm   664 IESLVGRSQM---PPAKTSLKEKITEETE 689

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG13325	NP_001286373.1	NRF	85..198	CDD:214781	35/118 (30%)
		Acyl_transf_3	268..648	CDD:280013	122/432 (28%)
		OafA	299..654	CDD:224748	114/407 (28%)
oac-31	NP_503441.2	NRF	80..184	CDD:214781	35/118 (30%)
oac-31	NP_503441.2	OafA	253..659	CDD:224748	124/437 (28%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	204	1.000	Domainoid score	I1719
eggNOG	1	0.900	-	-		E1_KOG3700
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	238	1.000	Inparanoid score	I2120
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1171418at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm14368
orthoMCL	1	0.900	-	-		OOG6_100705
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X299
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	11	10.730