DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG13325 and oac-46

DIOPT Version :9

Sequence 1:	NP_001286373.1	Gene:	CG13325 / 36437	FlyBaseID:	FBgn0033792	Length:	697	Species:	Drosophila melanogaster
Sequence 2:	NP_495886.2	Gene:	oac-46 / 174415	WormBaseID:	WBGene00011768	Length:	676	Species:	Caenorhabditis elegans

Alignment Length:	753	Identity:	176/753 - (23%)
Similarity:	299/753 - (39%)	Gaps:	150/753 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 IVFLLCGFVIISAGNPNSDD-VLPQFRNVRQLRSLGIE-------FTEYFRNIST---QDLGGLE 59
            :..||....|.|||....|: .:.||.|..|...|.::       ..:|..:|.|   |.:...|
Worm     5 LYLLLLSPAIASAGLEEYDEPFILQFINRSQTLDLSLKCKQSLALVYDYLNDIETLTDQKICYFE 69

  Fly    60 SQFSSEDDLLCLNDMKALMTGLGSAEYWALKMIDAWGSIPSGLLAGNSYDLGNFDECLNIRKEIG 124
            |..:..:||....|.          :.|..|                .|      |||     :.
Worm    70 SFATGPNDLFLSRDQ----------DRWVYK----------------GY------ECL-----LS 97

  Fly   125 QERTIQGK------YCFLSVSPAKILGIETSIGSFRTATCFPASCSAINMNAFVDQLMMKLLNVS 183
            ...|:..|      ||:......     :..:.:|  :.|.|:.|:..|     .:|:.:...::
Worm    98 AGETVYSKSEHPMHYCYTHDDDK-----DKRVPAF--SVCIPSPCADEN-----QKLLEEWRRIT 150

  Fly   184 VPSSAMRISEGSCQTSDSE-PWDALTIFMIVI---LSLMSFIVALSTLWDYFLVKDQDQLPA-IV 243
            .|.:...|:..:|..|..| .|..|.:.:...   :|| :.:|.::|::.....:|.....| |:
Worm   151 HPEATEPITFTACTRSRHEKQWFELPVPIADFGFNMSL-AMLVVMATIFHNMRGEDAKSWSARIL 214

  Fly   244 KICSARSNSRALFRVVESHSNPNVIDCLHGIRCMSLIWVITCHQY-SVTLISPHINLFRAATWVE 307
            ...||::|.:.|..:.:...  :.|.||.|:|..|::|.:..|.: .|.....::..|: .:.|:
Worm   215 LAFSAKTNLKKLIALPKDPQ--SCITCLLGLRFGSMVWTLIGHSFIFVQAYMENVEDFK-NSMVD 276

  Fly   308 KPFASFILHGFISVDSFLVIGGLLVALIPLRLMDKTKGKLNVP---------MMYLHRLIRIAP- 362
            ..|..:|.:..:|||.||.:||.:::....|...|...: ..|         ..|.||::|:.|
Worm   277 NFFNQWITNFTLSVDVFLTLGGTVLSYSWFRKWLKNTSE-EEPTWTSWGYWLKFYRHRVVRLYPA 340

  Fly   363 ----LLAMAI---VVHMKLM-----PLISSGPLFVGGYIGNSACKAGWYWTLLFVNNYTDAKCLA 415
                |||:.:   |.|...|     |.|.              |...|:..:||||:..|.:|:.
Worm   341 YLYTLLAVTLRISVTHFHPMWPPTDPAIQ--------------CPKYWWQNVLFVNSILDNQCMP 391

  Fly   416 QSWYLSLDMQLYIISPILLISLYKWGKKAAAGIFIL---IILLSACLFATMMV--NGYSMMITAA 475
            .:||:..:...|::|||.|::|    :||....|||   :|:.||.|....:|  |.........
Worm   392 WTWYIGTEFIYYLLSPIFLLTL----RKAPKIGFILCFVVIMFSAGLNVESIVRNNFPPTQFLWK 452

  Fly   476 SPEAMRDGYYATHT--------HATPWLIGFLFGYFLHLNRGKKF----QLSWVSVWSGWILCLA 528
            .||.....:...|.        ...|:|||.|.||  .|.|.::.    |.|...:.|.|.:.|.
Worm   453 QPEMFNPNFIQHHLELYIKPQYRIGPYLIGILLGY--QLARYQRIPVKPQQSNKYIISMWSVALV 515

  Fly   529 MIFTSIFALYPPSKWSDPDASTLAESFYYTLTRVGWALALCWVIFACVQGYGGLANSFLASPLWQ 593
            .|...::.|||..:..|..|.......|..|.|..:::.:.::|:.|..|.||..|.||:|..:.
Worm   516 GILFGLYGLYPALQGWDSIAWRAYHLLYGALHRDIFSIGIAFLIYICHTGIGGPVNVFLSSNFFL 580

  Fly   594 PLSRLSYSVFIWHMFFMEMNARSTRTSTYF-SDYGMMLNFWSTLGFTLLFSYAMHLLIEAPIGGL 657
            ||:.||:|.:::||..:.:.........|| :...:.::.:..|..|..|:....::.|.|...:
Worm   581 PLANLSFSAYLFHMIPVVLTYMLVPFPIYFNTQIPLFIHCFVQLLITYFFAIICTMVSELPALNI 645

  Fly   658 DIFL---RPKGKISPTEKQTSHIDDKEPRDPENLLEPT 692
            :..|   .||..:.|:          .|.|.|..|:|:
Worm   646 ERLLLASPPKTTLKPS----------PPTDSEIQLKPS 673

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG13325	NP_001286373.1	NRF	85..198	CDD:214781	19/118 (16%)
		Acyl_transf_3	268..648	CDD:280013	110/420 (26%)
		OafA	299..654	CDD:224748	102/394 (26%)
oac-46	NP_495886.2	OafA	279..653	CDD:224748	102/394 (26%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3700
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1171418at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X299
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	6	5.780