DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG13325 and oac-9

DIOPT Version :9

Sequence 1:	NP_001286373.1	Gene:	CG13325 / 36437	FlyBaseID:	FBgn0033792	Length:	697	Species:	Drosophila melanogaster
Sequence 2:	NP_491809.2	Gene:	oac-9 / 172323	WormBaseID:	WBGene00016753	Length:	820	Species:	Caenorhabditis elegans

Alignment Length:	779	Identity:	168/779 - (21%)
Similarity:	308/779 - (39%)	Gaps:	197/779 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 FLLCGFVIISAGNPNSDDVLPQ-FRNVRQLRSLGIEFTEYFRNISTQDLGGLESQFSSEDDLLCL 71
            |:.|.|      ..:...:|.| |...:...:...:|.|.|:|.              |||..|:
Worm    17 FVSCSF------TKSGKQILQQIFEGDKDNHTKFNKFQELFKNF--------------EDDSFCI 61

  Fly    72 NDM----KALMTGLGSAE-------YWALKMIDAWGSIPSGL-LAGNSYDLGNFDECLNIRKEIG 124
            |.:    |:.:..|....       .||:::||:..:.|.|| ..|..:.:|:|:.|    ||:.
Worm    62 NSLGNIGKSALKFLSECSSNTCLEPNWAVRLIDSLPTKPPGLSRKGPFFFIGDFETC----KELW 122

  Fly   125 QERTIQGKYCFLSVSPAKILGIETSIGSFRTATCFPASCSAINMNAFVDQLMMKLLNVSVPSSAM 189
            .....|..||.|..:..  ||.||.  ...|..|.|::|....|:..::.....|.|.::...::
Worm   123 SVEHRQVHYCTLKGTVK--LGSETL--PVTTGVCLPSNCHENQMSKLLNLAKEYLFNETIHVDSV 183

  Fly   190 RISEGSCQT-SDSEPWDALTIFMIVILSLMSFIVALSTLWDYF----LVK--------------- 234
            ..|.|:..| |..:|:...::|.|:.|      :.:.||.:..    |:|
Worm   184 YCSHGTDSTWSVKKPFVLFSLFFILAL------LTIGTLTEKMNRDGLIKKSNTKMRRMIHKKSF 242

  Fly   235 -----------------------------DQDQL----------PAI-----------------V 243
                                         |.:.|          |:|                 |
Worm   243 DVTRSSAVSISEDRSDRESCGFDSSGESEDNESLANSSVNRQFAPSIALTYRTLATISLSNSLLV 307

  Fly   244 KICSA---RSNSRALFRVVESHSNPNVIDCLHGIRCMSLIWVITCHQYSVTLISPHI-NLFRAAT 304
            .|.||   ||:...|||     ::...:..::..|..|..|||..|   ..|.|.|. :..|:..
Worm   308 NILSAFSVRSSLTYLFR-----NSTRDVKLVNLFRVCSSFWVIFSH---TCLFSLHFTDTIRSVA 364

  Fly   305 --------WVEKPFASFILHGFISVDSFLVIGGLLVALIPLRLMDKTKGKLN----VPMMYL--H 355
                    |     .:|:::..::||:||.:.. .||...:|.....:|..:    :..:.|  |
Worm   365 RKGESVVGW-----RNFMMNSSLAVDTFLFLSA-CVASYSIRKKILFRGSSSNFSIIKCLALLGH 423

  Fly   356 RLIRIAPLLAMAIVVHMKLMPLISSGPLFVGGYIGNSACKAGWYWT-LLFVNNYTDAKCLAQSWY 419
            |.:|:.|.|::.::....:...::.||.:....:..:.|.....|. ..||:|:..:.|:...||
Worm   424 RCLRLLPALSLYLLFMGLVYNHLADGPFWNANGMFGTECNVTTIWPHFAFVSNFFPSTCVPWLWY 488

  Fly   420 LSLDMQLYIISPILL--ISLYKWGKKAAAGIFILIILLSACLFA--TMMVNGYSMMITAASPEA- 479
            :|||.|||:..||::  :|.:::|...|..:.||.::..:.::|  |:..|.:..|::....:|
Worm   489 ISLDFQLYLTLPIVIFFLSKFRFGFTFAIVLCILALVYRSLMYAIYTLPANMFVEMLSGKFEKAE 553

  Fly   480 --MRDGYYATHTHATPWLIGFLFGYFLHLNRGKKFQLSWV----SVWSGWILCLAMIFTSIFALY 538
              .:..|.:..:...|:.:|.|.|:::       .|:.::    |:.|..:..||:...: |||:
Worm   554 LSFKLLYTSPLSRCPPFFLGILTGWYI-------CQIRYLGTLRSITSFGLKILAVSLLA-FALF 610

  Fly   539 PPSKWSD----PDASTLAESFYYTLTRVGWALALCWVIFACVQGYG-GLANSFLASPLWQPLSRL 598
            .|..:|:    |.|.:         .|:.||..|..::.....||. |:...|....| ..||||
Worm   611 GPFFYSEFLTYPHAIS---------NRILWASGLAILVVLAQNGYNFGVFKVFGGQTL-VVLSRL 665

  Fly   599 SYSVFIWH----MFFMEMNARSTRTSTYFSDYGMMLNFWSTLGFTLLFSYAMHLLIEAPIGGLD 658
            |:.|::.|    ::::. :.|...:.|.|. |.|.:.. |....:|:.::.:.:.||.|:..|:
Worm   666 SFGVYLSHEPILLYYLN-SLRQPMSPTSFG-YFMFITI-SIYVLSLVCAFFIAISIEVPLLNLE 726

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG13325	NP_001286373.1	NRF	85..198	CDD:214781	30/120 (25%)
		Acyl_transf_3	268..648	CDD:280013	94/415 (23%)
		OafA	299..654	CDD:224748	87/389 (22%)
oac-9	NP_491809.2	NRF	88..187	CDD:214781	28/106 (26%)
oac-9	NP_491809.2	Acyl_transf_3	333..715	CDD:376607	94/411 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3700
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1171418at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11161
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	5	4.880