DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG13325 and oacyl

DIOPT Version :9

Sequence 1:	NP_001286373.1	Gene:	CG13325 / 36437	FlyBaseID:	FBgn0033792	Length:	697	Species:	Drosophila melanogaster
Sequence 2:	XP_021324686.1	Gene:	oacyl / 100002566	ZFINID:	ZDB-GENE-090710-2	Length:	676	Species:	Danio rerio

Alignment Length:	691	Identity:	174/691 - (25%)
Similarity:	293/691 - (42%)	Gaps:	133/691 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly    48 RNISTQDLGGLESQFSSEDDLLCLNDMKALMTGL--GSAEYWALKMIDAWGSIPSGLLAGNSYDL 110
            ||:|                |.|::|....:..|  .:...:|:.|.||:|.|.|.:..||....
Zfish    23 RNVS----------------LKCVDDTMGFLMELQKETPSKFAVIMYDAFGKIGSDVEGGNVNRP 71

  Fly   111 GNFDECLNIRKEIGQERTIQGKYCFLSVSPAKILGIETSIGSFRTATCFPASCSAINMNAFV--- 172
            |:..|||::     :....:|:||.:.:...|   :|..:|     .|.|.||:...:...|
Zfish    72 GSLRECLSV-----EGPGFRGQYCQVFLKQDK---VEYFVG-----VCVPDSCTDSEVQTLVIHE 123

  Fly   173 --DQLMMKLL----NVSVPSSAMRISEGSCQTSDSEPWDALTIFMIVILSLMSFIVALSTLWDYF 231
              .:..|.||    ::.:|.|.:.|....|. |||...|   :..||.||:...::||..:...|
Zfish   124 AFQKQQMSLLPSVPSILIPDSTLGIFMTQCH-SDSPNID---LSAIVCLSVCCALLALPLIASIF 184

  Fly   232 LV----KDQDQLPAIV-----------------------KICS------------ARSNSRALFR 257
            :.    |...::..:|                       |.||            |.|..::|.:
Zfish   185 VALIKRKQMREVAPVVGLAQTSNSKQYGTVLTNGSANQNKECSPDLDTTQTKTQNAESKQQSLSK 249

  Fly   258 VVES--------HSNPNVID---------CLHGIRCMSLIWVITCHQYSVTLISPHINLFRAATW 305
            .|.|        :.:..::|         .|:|||.:||.|:|:.|....:..|   :|.....|
Zfish   250 TVVSWLQGFSVQNCSQGLLDTEGSGRSYSSLNGIRILSLFWIISGHTVHFSAWS---HLDNEKRW 311

  Fly   306 VE----KPFASFILHG--FISVDSFLVIGGLLVALIPLRLMDKTKGKLNVPMM--YL-HRLIRIA 361
            .|    .|.......|  :::||||||:||||.|...|..:.::...|:|.::  || .|..||.
Zfish   312 KEMVENNPLYVLTFSGPVYLAVDSFLVLGGLLSAKSLLGTIRRSDNTLSVGLVVNYLFKRFKRIQ 376

  Fly   362 PLLAMAIVVHMKLMPLISSGPLFVGGYIGNSACKAGWYWTLLFVNN---YTDAKCLAQSWYLSLD 423
            ||....:.:.:.|..::..|..:........:||..|:..||.:||   .||. |...:||||:|
Zfish   377 PLHLFIVCLVISLFSVVPRGVFWFFAEDQVLSCKKYWWSNLLLINNLLTITDI-CAPWTWYLSID 440

  Fly   424 MQLYIISPILLISLYKWGKKAAAGIFILIILLSA---CLFATMMVNGYSMMITAASPEAMRDGYY 485
            .|.|..:| |||.||:..|.|...:.:::::||:   .|..:.:........|.|.....:..|.
Zfish   441 FQFYATTP-LLIFLYRMNKCALVVVSVVLLMLSSVTGALITSFLHLPVHQPTTLAYESYFQYYYN 504

  Fly   486 ATHTHATPWLIGFLFGYFLHLNRGKKFQLSWVSVWSGWILCLAMIFTSIFALY-----PPSKWSD 545
            ..:|...|:|:|.|.|.::...:....:..|.:| .||:..|:::...:...|     ||.
Zfish   505 KPYTRYGPYLLGVLAGIYMTTKKEALIKHQWQAV-IGWLCSLSVMALLVGLAYVLRDVPPH---- 564

  Fly   546 PDASTLAESFYYTLTRVGWALALCWVIFACVQGYGGLANSFLASPLWQPLSRLSYSVFIWHMFFM 610
               .::..:.|..:.|..|||||.|:|.||.:||||..::||:..||.|||.:|::.::.|...:
Zfish   565 ---LSIPHAIYQGIHRSLWALALIWIILACEEGYGGFVDTFLSLSLWAPLSNISFACYLIHPIII 626

  Fly   611 EMNARSTRTSTYFSDYGMMLNFWSTLGFTLLFSYAMHLLIE 651
            .:.......:.:::|:.....|...|..::...|.:.:|||
Zfish   627 ILYNGKQEITMHYTDFNFFYLFLGHLVLSIFIGYVLTVLIE 667

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG13325	NP_001286373.1	NRF	85..198	CDD:214781	31/121 (26%)
		Acyl_transf_3	268..648	CDD:280013	112/408 (27%)
		OafA	299..654	CDD:224748	104/373 (28%)
oacyl	XP_021324686.1	NRF	48..120	CDD:214781	23/84 (27%)
oacyl	XP_021324686.1	OafA	273..668	CDD:224748	114/408 (28%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170588167
Domainoid	1	1.000	50	1.000	Domainoid score	I11639
eggNOG	1	0.900	-	-		E1_KOG3700
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H129774
Inparanoid	1	1.050	178	1.000	Inparanoid score	I4016
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1171418at2759
OrthoFinder	1	1.000	-	-		FOG0001682
OrthoInspector	1	1.000	-	-		otm25504
orthoMCL	1	0.900	-	-		OOG6_100705
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X299
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	13	12.660