DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Drl-2 and KIN1

DIOPT Version :9

Sequence 1:	NP_001286371.1	Gene:	Drl-2 / 36436	FlyBaseID:	FBgn0033791	Length:	648	Species:	Drosophila melanogaster
Sequence 2:	NP_010407.1	Gene:	KIN1 / 851700	SGDID:	S000002529	Length:	1064	Species:	Saccharomyces cerevisiae

Alignment Length:	398	Identity:	78/398 - (19%)
Similarity:	152/398 - (38%)	Gaps:	83/398 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly   295 AETIYSKPESICPSRISYYASS---QLTQPCSLSTPKSIRSNGNGN---CTSGSGSLSLFG---- 349
            :.:::::|.::.|:.:.....|   |..|...|..|..|:...|||   .......:.|.|
Yeast    25 SNSMHTQPSTMAPATLRMMGKSPQQQQQQNTPLMPPADIKYANNGNSHQAEQKERQVELEGKSRE 89

  Fly   350 GIPTGSTITMASHGEKGNQRLRRITSVQP----------GALSYEELVKEGTFGRIYAGKLGESC 404
            ..|..:|.:.:           |::|.|.          |...:.|.|..|:.|::...|...:.
Yeast    90 NAPKPNTTSQS-----------RVSSSQGMPKQFHRKSLGDWEFVETVGAGSMGKVKLAKHRYTN 143

  Fly   405 EALVKTVIDGAS-----------------------------LTQVACLLQDASLLIGVSHQHILA 440
            |.....:::.|:                             :::....:::|||...:.|.|| .
Yeast   144 EVCAVKIVNRATKAFLHKEQMLPPPKNEQDVLERQKKLEKEISRDKRTIREASLGQILYHPHI-C 207

  Fly   441 PLLANTELPGPPEIAYPHPSKGNLKMYLQKSRESSTALSTRQLVEFGLHITKGLAYLHSLGIVHK 505
            .|.....|.....:.:.:.|.|.|..|:.:    ..::...|..:|...|...|.|||:..|||:
Yeast   208 RLFEMCTLSNHFYMLFEYVSGGQLLDYIIQ----HGSIREHQARKFARGIASALIYLHANNIVHR 268

  Fly   506 DIATRNCYLDEESYVKICDSALSRDLFPDDYDCLGDNENR------PLKWLSLESLQKRVY-ATQ 563
            |:...|..:.:.|.:||.|..||.         :.|:..:      .|.:.:.|.|:...| ..:
Yeast   269 DLKIENIMISDSSEIKIIDFGLSN---------IYDSRKQLHTFCGSLYFAAPELLKANPYTGPE 324

  Fly   564 GDVWALGVTYWELVTLAQMPHEEVDIFELTNYLAAGFRLEQPVNCPDEFFTVMNCCWHCEAKQRP 628
            .|||:.||..:.|| ..::|.::.:...|...:..| ::|.|.:...|..::::.....:.|:|.
Yeast   325 VDVWSFGVVLFVLV-CGKVPFDDENSSVLHEKIKQG-KVEYPQHLSIEVISLLSKMLVVDPKRRA 387

  Fly   629 TPSQLLSY 636
            |..|::.:
Yeast   388 TLKQVVEH 395

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Drl-2	NP_001286371.1	WIF	37..156	CDD:280237
		PTK_Ryk	373..644	CDD:270639	62/310 (20%)
		STYKc	389..637	CDD:214568	57/284 (20%)
KIN1	NP_010407.1	STKc_Kin1_2	118..398	CDD:270979	60/294 (20%)
KIN1	NP_010407.1	MARK_C_like	890..1062	CDD:213377
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	0	0.000