Protein Alignment Drl-2 and ryk

DIOPT Version :9

• Sequence 1: NP_001286371.1
• Gene: Drl-2 / 36436
• FlyBaseID: FBgn0033791
• Length: 648
• Species: Drosophila melanogaster
• Sequence 2: XP_012825927.1
• Gene: ryk / 550026
• XenbaseID: XB-GENE-485290
• Length: 601
• Species: Xenopus tropicalis
• Alignment Length: 660
• Identity: 198/660 - (30%)
• Similarity: 319/660 - (48%)
• Gaps: 150/660 - (22%)

  Fly    27 LNIFISHHEVMKLMGLEADLFYVHEGAINTYAMHFTVPVPADVHELEFSW--QSLIAYPLPYAIS 89
            ||:::|..||.:|:||:|:|:|:....||.||:.|.:.||::.:.|.|:|  :|.:.|.|.:.:
 Frog    54 LNLYLSEEEVRRLIGLDAELYYIRNDIINHYALSFNLLVPSETNSLHFTWHAKSKVEYKLGFQV- 117

  Fly    90 IEYNNDQEALGTPTLSIPHKGLVPQEIESFLVYLPCTGNASLQMPVNVNMVVRAPPRFNDTRLHF 154
                ::..|:..|..:|..:|.||..:..|.|.|.|:|....::...:.:.:......|.|.|:|
 Frog   118 ----DNPMAMTMPLTNISMQGEVPSSLTVFRVDLYCSGKMDSEVLFLMQLNITISSAKNITVLNF 178

  Fly   155 KRNKICAKGISPEPNQSPA------------PAH-APSQGPAL--LSAAACALGLVLAVGLVASM 204
            ||.|:|.:.:  |..:.|.            |.: ||:....:  :|...|. .::..|.::.::
 Frog   179 KRRKMCYRKL--EDIKVPVLQDKNNTRIHFDPVNVAPTTSTRVFYISVGVCC-AVIFLVAIILAV 240

  Fly   205 MYVRARKQLRQDSLHTSFTTAAYGSHQNVFIRLDPLGRPPSATGSYATIASLNKYPADSKKSCSI 269
            :::.:.|::..|                                             ||....|
 Frog   241 LHLHSMKRVELD---------------------------------------------DSMSDSS- 259

  Fly   270 FDRFRSSPTPTPYATALLPMNLEQTAETIYSKPESICPSRISYYASSQLTQPCSLSTPKSIRSNG 334
                                                        :|..|:|| |..|.:.:|::.
 Frog   260 --------------------------------------------SSQGLSQP-STQTTQYLRADT 279

  Fly   335 NGNCTSGSGSLSLFGGIPTGSTITMASHGEKGNQRLRRIT------SVQPGALSYE-----ELVK 388
            ..|.|..:.|    .|.||       ...||.:  |:.:|      .|:..|:|.|     ::::
 Frog   280 PNNATPVTSS----SGYPT-------LRIEKND--LKSVTLQEAKAKVKDIAISRERVTLKDVLQ 331

  Fly   389 EGTFGRIYAGKLGESCE------ALVKTVIDGASLTQVACLLQDASLLIGVSHQHILAPLLANTE 447
            |||||||:.|.|.:..:      ..||||.|.||..|:..:|.::..|.|:.|:::|......||
 Frog   332 EGTFGRIFHGILVDEKDPNKEKAVFVKTVKDQASEVQITMMLTESCKLRGLHHRNLLPIGHVCTE 396

  Fly   448 LPGPPEIAYPHPSKGNLKMYLQKSR----ESSTALSTRQLVEFGLHITKGLAYLHSLGIVHKDIA 508
            ....|.:..|:.:.||||::|::.:    .:..|:|.:.||...:.|..|::||....::|||:|
 Frog   397 DGEKPMVLLPYMNWGNLKLFLRQCKLVEANNPQAISQQDLVHMAIQIACGMSYLARREVIHKDLA 461

  Fly   509 TRNCYLDEESYVKICDSALSRDLFPDDYDCLGDNENRPLKWLSLESLQKRVYATQGDVWALGVTY 573
            .|||.:||...|||.|:||||||||.||.|||||||||::|::||||..:.:::.|||||.|||.
 Frog   462 ARNCVIDESLQVKITDNALSRDLFPMDYHCLGDNENRPVRWMALESLVNKEFSSAGDVWAFGVTL 526

  Fly   574 WELVTLAQMPHEEVDIFELTNYLAAGFRLEQPVNCPDEFFTVMNCCWHCEAKQRPTPSQLLSYLQ 638
            |||:||.|.|:.::|.||:..||..|:|:.||:|||||.|.||.|||..:.::||...||:..|.
 Frog   527 WELMTLGQTPYVDIDPFEMAAYLKDGYRIAQPINCPDELFAVMACCWALDPEERPKFQQLVQCLT 591

  Fly   639 DFHADLGMYI 648
            :||:.||.|:
 Frog   592 EFHSALGAYV 601

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Drl-2	NP_001286371.1	WIF	37..156	CDD:280237	34/120 (28%)
		PTK_Ryk	373..644	CDD:270639	123/291 (42%)
		STYKc	389..637	CDD:214568	115/257 (45%)
ryk	XP_012825927.1	WIF	57..180	CDD:366878	37/127 (29%)
		PTK_Ryk	317..597	CDD:270639	121/279 (43%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	88	1.000	Domainoid score	I7805
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H68287
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D359098at33208
OrthoFinder	1	1.000	-	-		FOG0005256
OrthoInspector	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24416
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X3777
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	8	8.020