| Sequence 1: | NP_001286371.1 | Gene: | Drl-2 / 36436 | FlyBaseID: | FBgn0033791 | Length: | 648 | Species: | Drosophila melanogaster |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_001973.2 | Gene: | ERBB3 / 2065 | HGNCID: | 3431 | Length: | 1342 | Species: | Homo sapiens |
| Alignment Length: | 693 | Identity: | 161/693 - (23%) |
|---|---|---|---|
| Similarity: | 258/693 - (37%) | Gaps: | 171/693 - (24%) |
- Green bases have known domain annotations that are detailed below.
|
Fly 27 LNIFISHHEVMKLMGLEADLFYVHEGAINTYAMHFTVPVPADVHELEFSWQSLIA----YPLPYA 87
Fly 88 ISIEYNNDQEALGTPTLSIPHKGLVPQEIESFLVYLPCTGNASLQMPVNVNMVVRAPPRFNDTRL 152
Fly 153 HFKRNK----ICAKGISPEPNQSPAPAHAPSQGPALLSAAACALGLVLAVGLVASMMYVRARKQL 213
Fly 214 RQDSLHTSFTTA--AYGSHQNVFIRLDPLGRPPSATGSYATIASLNKYPADSKKSCSIFDRFRSS 276
Fly 277 PTPTPYATALLPMNLEQTAETIYSKP--ESICPSRISYYASSQLTQPCSLSTPKSIRSNGNGNCT 339
Fly 340 SG-----------------------------SGSLSLF---GG-------------------IPT 353
Fly 354 GSTITMASHGEKGNQRLRRITSVQPGALSYEELVKEGTFGRIYAG---KLGESCE--ALVKTVID 413
Fly 414 GASLTQVACLLQDASLLIG-VSHQHI--LAPLLANTELPGPPEIAYPHPSKGNLKMYLQKSRESS 475
Fly 476 TALSTRQLVEFGLHITKGLAYLHSLGIVHKDIATRNCYLDEESYVKICDSALSRDLFPDDYDCLG 540
Fly 541 DNENRPLKWLSLESLQKRVYATQGDVWALGVTYWELVTLAQMPHEEVDIFELTNYLAAGFRLEQP 605
Fly 606 VNCPDEFFTVMNCCWHCEAKQRPTPSQLLSYLQDFHADLGMYI 648 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| Drl-2 | NP_001286371.1 | WIF | 37..156 | CDD:280237 | 21/122 (17%) |
| PTK_Ryk | 373..644 | CDD:270639 | 87/278 (31%) | ||
| STYKc | 389..637 | CDD:214568 | 85/255 (33%) | ||
| ERBB3 | NP_001973.2 | Recep_L_domain | 56..167 | CDD:279382 | |
| FU | 180..215 | CDD:214589 | |||
| Furin-like | 183..329 | CDD:279142 | |||
| FU | 226..266 | CDD:238021 | |||
| Recep_L_domain | 353..474 | CDD:279382 | 20/117 (17%) | ||
| GF_recep_IV | 499..630 | CDD:291509 | 32/189 (17%) | ||
| FU | 500..553 | CDD:238021 | 11/73 (15%) | ||
| FU | 548..592 | CDD:214589 | 11/56 (20%) | ||
| TM_ErbB3 | 638..676 | CDD:213056 | 4/37 (11%) | ||
| PTK_HER3 | 701..979 | CDD:173656 | 90/286 (31%) | ||
| Pkinase_Tyr | 709..965 | CDD:285015 | 86/263 (33%) | ||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 980..999 | ||||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 1033..1152 | ||||
| Blue background indicates that the domain is not in the aligned region. | |||||
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 0 | 0.000 | Not matched by this tool. | |||
| Domainoid | 0 | 0.000 | Not matched by this tool. | |||
| eggNOG | 1 | 0.900 | - | - | E1_KOG1025 | |
| Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
| Homologene | 0 | 0.000 | Not matched by this tool. | |||
| Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
| Isobase | 0 | 0.000 | Not matched by this tool. | |||
| OMA | 0 | 0.000 | Not matched by this tool. | |||
| OrthoDB | 0 | 0.000 | Not matched by this tool. | |||
| OrthoFinder | 0 | 0.000 | Not matched by this tool. | |||
| OrthoInspector | 0 | 0.000 | Not matched by this tool. | |||
| orthoMCL | 0 | 0.000 | Not matched by this tool. | |||
| Panther | 0 | 0.000 | Not matched by this tool. | |||
| Phylome | 1 | 0.910 | - | - | ||
| RoundUp | 0 | 0.000 | Not matched by this tool. | |||
| SonicParanoid | 0 | 0.000 | Not matched by this tool. | |||
| SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
| TreeFam | 0 | 0.000 | Not matched by this tool. | |||
| User_Submission | 0 | 0.000 | Not matched by this tool. | |||
| 2 | 1.810 | |||||