Sequence 1: | NP_001286371.1 | Gene: | Drl-2 / 36436 | FlyBaseID: | FBgn0033791 | Length: | 648 | Species: | Drosophila melanogaster |
---|---|---|---|---|---|---|---|---|---|
Sequence 2: | NP_997538.1 | Gene: | Egfr / 13649 | MGIID: | 95294 | Length: | 1210 | Species: | Mus musculus |
Alignment Length: | 447 | Identity: | 108/447 - (24%) |
---|---|---|---|
Similarity: | 174/447 - (38%) | Gaps: | 97/447 - (21%) |
- Green bases have known domain annotations that are detailed below.
Fly 288 PMNLEQTAETIYSKPESI-------CPSR-------ISYYASSQLTQPCSLSTPKSIRSNGN--- 335
Fly 336 --------------GNCTSGSGSLSLFG--GIPTGSTITMASHGEKG------------------ 366
Fly 367 -----NQRLRRITS----VQPGALSYE-------ELVKE-----------GTFGRIYAG---KLG 401
Fly 402 ESCE--ALVKTVIDGASLTQVACLLQDASLLIGVSHQHI---LAPLLANTELPGPPEIAYPHPSK 461
Fly 462 GNLKMYLQKSRESSTALSTRQLVEFGLHITKGLAYLHSLGIVHKDIATRNCYLDEESYVKICDSA 526
Fly 527 LSRDLFPDDYDCLGDNENRPLKWLSLESLQKRVYATQGDVWALGVTYWELVTLAQMPHEEVDIFE 591
Fly 592 LTNYLAAGFRLEQPVNCPDEFFTVMNCCWHCEAKQRPTPSQLLSYLQDFHADLGMYI 648 |
Gene | Sequence | Domain | Region | External ID | Identity |
---|---|---|---|---|---|
Drl-2 | NP_001286371.1 | WIF | 37..156 | CDD:280237 | |
PTK_Ryk | 373..644 | CDD:270639 | 80/300 (27%) | ||
STYKc | 389..637 | CDD:214568 | 75/266 (28%) | ||
Egfr | NP_997538.1 | Recep_L_domain | 57..168 | CDD:279382 | |
Approximate | 75..300 | ||||
Furin-like | 184..335 | CDD:279142 | |||
FU | 231..274 | CDD:238021 | |||
Recep_L_domain | 362..481 | CDD:279382 | |||
Approximate | 390..600 | 10/56 (18%) | |||
GF_recep_IV | 505..636 | CDD:291509 | 17/92 (18%) | ||
FU | 506..559 | CDD:238021 | 3/12 (25%) | ||
FU | 552..598 | CDD:214589 | 9/48 (19%) | ||
TM_ErbB1 | 634..679 | CDD:213054 | 6/44 (14%) | ||
Important for dimerization, phosphorylation and activation. /evidence=ECO:0000250 | 690..706 | 4/15 (27%) | |||
PTKc_EGFR | 706..1018 | CDD:270683 | 78/284 (27%) | ||
TyrKc | 715..970 | CDD:197581 | 74/262 (28%) | ||
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 1113..1137 | ||||
Blue background indicates that the domain is not in the aligned region. |
Tool | Simple Score | Weighted Score | Original Tool Information | |||
---|---|---|---|---|---|---|
BLAST Result | Score | Score Type | Cluster ID | |||
Compara | 0 | 0.000 | Not matched by this tool. | |||
Domainoid | 0 | 0.000 | Not matched by this tool. | |||
eggNOG | 1 | 0.900 | - | - | E1_KOG1025 | |
Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
Homologene | 0 | 0.000 | Not matched by this tool. | |||
Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
Isobase | 0 | 0.000 | Not matched by this tool. | |||
OMA | 0 | 0.000 | Not matched by this tool. | |||
OrthoDB | 0 | 0.000 | Not matched by this tool. | |||
OrthoFinder | 0 | 0.000 | Not matched by this tool. | |||
OrthoInspector | 0 | 0.000 | Not matched by this tool. | |||
orthoMCL | 0 | 0.000 | Not matched by this tool. | |||
Panther | 0 | 0.000 | Not matched by this tool. | |||
Phylome | 0 | 0.000 | Not matched by this tool. | |||
RoundUp | 0 | 0.000 | Not matched by this tool. | |||
SonicParanoid | 0 | 0.000 | Not matched by this tool. | |||
SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
TreeFam | 0 | 0.000 | Not matched by this tool. | |||
1 | 0.900 |