Protein Alignment Su(z)2 and PCGF6

DIOPT Version :10

• Sequence 1: NP_001260933.1
• Gene: Su(z)2 / 36432
• FlyBaseID: FBgn0265623
• Length: 1396
• Species: Drosophila melanogaster
• Sequence 2: NP_001011663.1
• Gene: PCGF6 / 84108
• HGNCID: 21156
• Length: 350
• Species: Homo sapiens
• Alignment Length: 197
• Identity: 55/197 - (27%)
• Similarity: 96/197 - (48%)
• Gaps: 24/197 - (12%)

  Fly    33 ITCRLCRGYMIDPTTVDYCYHTYCRSCILKHLLRAVYCPECKASGGKEINELNLKSDDTLRSLIY 97
            |.|.:|:||:||.||:..|.||:|:|||::|...:..||:|.....:.....|::.|..|:.::|
Human   132 ILCSICKGYLIDATTITECLHTFCKSCIVRHFYYSNRCPKCNIVVHQTQPLYNIRLDRQLQDIVY 196

  Fly    98 KLVPGLYQRECKELADFKEQHDL-VDEQTTDEP--------------EFFTTTEL-ISLSLEYHP 146
            |||..|.:||.|::.||.::..| |.:....:|              .|....|| :||.||:..
Human   197 KLVINLEEREKKQMHDFYKERGLEVPKPAVPQPVPSSKGRSKKVLESVFRIPPELDMSLLLEFIG 261

  Fly   147 AMLHQCGPGEVPP--TIYLQCAAGLPVELLKRFLCSKYNIETDNGLVEVEVTYKDEVLPTNFTLM 209
            |   ..|.|...|  ..:::.:....:..:::||..|..::.   ..:|::...|.:|....||.
Human   262 A---NEGTGHFKPLEKKFVRVSGEATIGHVEKFLRRKMGLDP---ACQVDIICGDHLLEQYQTLR 320

  Fly   210 DV 211
            ::
Human   321 EI 322

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Su(z)2	NP_001260933.1	RING-HC_PCGF5	23..117	CDD:438395	33/83 (40%)
		RAWUL_PCGF2_like	137..228	CDD:340602	17/78 (22%)
PCGF6	NP_001011663.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..115
		RING-HC_PCGF5	125..215	CDD:438395	33/82 (40%)
		RAWUL_PCGF6	252..341	CDD:340605	16/77 (21%)