Protein Alignment Su(z)2 and PCGF2

DIOPT Version :9

• Sequence 1: NP_001260933.1
• Gene: Su(z)2 / 36432
• FlyBaseID: FBgn0265623
• Length: 1396
• Species: Drosophila melanogaster
• Sequence 2: NP_001356543.1
• Gene: PCGF2 / 7703
• HGNCID: 12929
• Length: 344
• Species: Homo sapiens
• Alignment Length: 312
• Identity: 95/312 - (30%)
• Similarity: 146/312 - (46%)
• Gaps: 45/312 - (14%)

  Fly    26 VRQFHDLITCRLCRGYMIDPTTVDYCYHTYCRSCILKHLLRAVYCPECKASGGKEINELNLKSDD 90
            :.:.:..:.|.||.||.||.||:..|.|::|::||:::|....|||.|.....|....|:::||.
Human     9 ITELNPHLMCALCGGYFIDATTIVECLHSFCKTCIVRYLETNKYCPMCDVQVHKTRPLLSIRSDK 73

  Fly    91 TLRSLIYKLVPGLYQRECKELADFKEQHDLVD----------EQTTDEPEFFTTTELISLSLEYH 145
            ||:.::|||||||::.|.|...||...:.|.:          |....|....:..|::|||:|::
Human    74 TLQDIVYKLVPGLFKDEMKRRRDFYAAYPLTEVPNGSNEDRGEVLEQEKGALSDDEIVSLSIEFY 138

  Fly   146 PAMLH--------QCGPGEVPPT--IYLQCAAGLPVELLKRFLCSKYNIETDNGLVEVEVTYKDE 200
            .....        :.|.|:...|  .:|:|.|.:.|..|.:||.:|.::.:.   .:|||.|:||
Human   139 EGARDRDEKKGPLENGDGDKEKTGVRFLRCPAAMTVMHLAKFLRNKMDVPSK---YKVEVLYEDE 200

  Fly   201 VLPTNFTLMDVAYCYNWSRESPMAFCYRI------LLYDNEQTKNDENNLSRINQDIEPEHSVRR 259
            .|...:||||:||.|.|.|..|:...||:      |......|.::..|.|..::.    .||
Human   201 PLKEYYTLMDIAYIYPWRRNGPLPLKYRVQPACKRLTLATVPTPSEGTNTSGASEC----ESV-- 259

  Fly   260 SKSAKSVTFAEDLESEIDS------GSPRSKVRCKTPPKVSPSSKNKRLTSS 305
            |..|.|........|.:.|      |||.|    ..||...|:|.....|:|
Human   260 SDKAPSPATLPATSSSLPSPATPSHGSPSS----HGPPATHPTSPTPPSTAS 307

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Su(z)2	NP_001260933.1	zf-C3HC4	35..73	CDD:278524	18/37 (49%)
		RAWUL	143..228	CDD:292824	29/94 (31%)
PCGF2	NP_001356543.1	RING-HC_PCGF4	12..65	CDD:319650	20/52 (38%)
		RING-HC finger (C3HC4-type)	18..56	CDD:319650	18/37 (49%)
		Nuclear localization signal. /evidence=ECO:0000255	81..95		8/13 (62%)
		RAWUL_PCGF2	130..228	CDD:340684	32/100 (32%)
		PLN02217	<236..328	CDD:215130	21/82 (26%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	240..344		20/78 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165157899
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2660
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000290
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10825
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	5	4.840