Protein Alignment Su(z)2 and RNF2

DIOPT Version :9

• Sequence 1: NP_001260933.1
• Gene: Su(z)2 / 36432
• FlyBaseID: FBgn0265623
• Length: 1396
• Species: Drosophila melanogaster
• Sequence 2: NP_009143.1
• Gene: RNF2 / 6045
• HGNCID: 10061
• Length: 336
• Species: Homo sapiens
• Alignment Length: 367
• Identity: 69/367 - (18%)
• Similarity: 124/367 - (33%)
• Gaps: 115/367 - (31%)

  Fly     3 LQNTHNTMESNAAMDAASPASRDVRQFHDLITCRLCRGYMIDPTTVDYCYHTYCRSCILKHLLRA 67
            ||.|.....::......||     |..|..:.|.:|...:.:..|...|.|.:|..||:..|...
Human    24 LQRTPQEAITDGLEIVVSP-----RSLHSELMCPICLDMLKNTMTTKECLHRFCADCIITALRSG 83

  Fly    68 -VYCPECKASGGKEINELNLKSDDTLRSLIYKLVPGLYQRECKELADFKEQHDLVDEQTTDEPEF 131
             ..||.|:.   |.:::.:|:.|....:||.|:.|.            :::::...|:.......
Human    84 NKECPTCRK---KLVSKRSLRPDPNFDALISKIYPS------------RDEYEAHQERVLARINK 133

  Fly   132 FTTTELISLSLEYHPAMLHQCGPGEVPPTIYLQCAAGLPVELLKRF-LCSKYNIET-----DNGL 190
            ....:.:|.|:|                       .||.::.:.|. ...|..||.     |||
Human   134 HNNQQALSHSIE-----------------------EGLKIQAMNRLQRGKKQQIENGSGAEDNG- 174

  Fly   191 VEVEVTYKDEVLPTNFTLMDVAYCYNWSRES-----PMAFCYRILLYDNEQTK-NDENNLSRINQ 249
                               |.::|.|.|..|     |          .|::|| :|::.|...|
Human   175 -------------------DSSHCSNASTHSNQEAGP----------SNKRTKTSDDSGLELDN- 209

  Fly   250 DIEPEHSVRRSKSAKSVTFAEDLESEIDSGSPRSKVRCKTPPKV--SPSSKNKRLTSSKREAEPE 312
                      :.:|.::....|..|||:       :..:..|.:  ...|...|...:...|..:
Human   210 ----------NNAAMAIDPVMDGASEIE-------LVFRPHPTLMEKDDSAQTRYIKTSGNATVD 257

  Fly   313 SPVSNFKSLRSNDMRYSDYAVSKVKSEPEQEQFLLPREREQQ 354
            . :|.:.::|        .|:.:::|:.|..|..|....|:|
Human   258 H-LSKYLAVR--------LALEELRSKGESNQMNLDTASEKQ 290

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Su(z)2	NP_001260933.1	zf-C3HC4	35..73	CDD:278524	11/38 (29%)
		RAWUL	143..228	CDD:292824	16/95 (17%)
RNF2	NP_009143.1	Interaction with HIP2. /evidence=ECO:0000269|PubMed:11513855	2..179		40/217 (18%)
		COG5222	<11..>103	CDD:227547	21/86 (24%)
		RING-HC_RING1_like	51..91	CDD:319445	11/39 (28%)
		Interaction with nucleosomes via an acidic patch on histone H2A and histone H2B. /evidence=ECO:0000269|PubMed:25355358	93..98		1/4 (25%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	157..208		17/80 (21%)
		RAWUL_RING2	225..330	CDD:340687	15/82 (18%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165157895
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.840