Protein Alignment Psc and PCGF2

DIOPT Version :9

• Sequence 1: NP_001286368.1
• Gene: Psc / 36431
• FlyBaseID: FBgn0005624
• Length: 1601
• Species: Drosophila melanogaster
• Sequence 2: NP_001356543.1
• Gene: PCGF2 / 7703
• HGNCID: 12929
• Length: 344
• Species: Homo sapiens
• Alignment Length: 434
• Identity: 136/434 - (31%)
• Similarity: 203/434 - (46%)
• Gaps: 107/434 - (24%)

  Fly   248 RPRPVLLTAVNPHIICHLCQGYLINATTIVECLHSFCHSCLINHLRKERFCPRCEMVINNAKP-- 310
            |...:.:|.:|||::|.||.||.|:||||||||||||.:|::.:|...::||.|::.::..:|
Human     3 RTTRIKITELNPHLMCALCGGYFIDATTIVECLHSFCKTCIVRYLETNKYCPMCDVQVHKTRPLL 67

  Fly   311 NIKSDTTLQAIVYKLVPGLYERELMRKRAFYKDRP-EEAALATPEQRGDDTEHLIFSPSDD--MS 372
            :|:||.|||.|||||||||::.|:.|:|.||...| .|....:.|.||:..|....:.|||  :|
Human    68 SIRSDKTLQDIVYKLVPGLFKDEMKRRRDFYAAYPLTEVPNGSNEDRGEVLEQEKGALSDDEIVS 132

  Fly   373 LSLEYAE--------LGELKT-DSEPELVDTLRPRYLQCPAMCRVSHLKKFVYDKFEIDAQRFSI 428
            ||:|:.|        .|.|:. |.:.|....   |:|:|||...|.||.||:.:|.::.: ::.:
Human   133 LSIEFYEGARDRDEKKGPLENGDGDKEKTGV---RFLRCPAAMTVMHLAKFLRNKMDVPS-KYKV 193

  Fly   429 DIMYKVKTIVLLDYYTLMDIAYIYTWKRDAPMRFYYRVYESPQPLVKPAPRRVLPLKLEKQEREN 493
            :::|:.:.  |.:|||||||||||.|:|:.|:...||        |:||.:|:
Human   194 EVLYEDEP--LKEYYTLMDIAYIYPWRRNGPLPLKYR--------VQPACKRL------------ 236

  Fly   494 QEQQLAVEVASSKVEPVSLPEDQKAEASIKVEEQESTREIVKEVIKDVAATPPTETLKLVINRNM 558
               .||           ::|...:...:....|.||        :.|.|.:|.|
Human   237 ---TLA-----------TVPTPSEGTNTSGASECES--------VSDKAPSPAT----------- 268

  Fly   559 LDKREKSHSPQMSSKSSSKSSPCTPV-SSPSEPNIKLKIDLSKQNSVTIIDMSDPERREIVKPLK 622
                       :.:.|||..||.||. .|||.                    ..|.......|..
Human   269 -----------LPATSSSLPSPATPSHGSPSS--------------------HGPPATHPTSPTP 302

  Fly   623 PEKESRSKKKDKDGSPKSSSSSSSSSSGERKRKSPSPLTVPPLT 666
            |...|.:......||.....:.||:|.|.:...:.:|  |||||
Human   303 PSTASGATTAANGGSLNCLQTPSSTSRGRKMTVNGAP--VPPLT 344

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Psc	NP_001286368.1	zf-C3HC4	263..301	CDD:278524	22/37 (59%)
		RAWUL	384..465	CDD:292824	29/81 (36%)
PCGF2	NP_001356543.1	RING-HC_PCGF4	12..65	CDD:319650	26/52 (50%)
		RING-HC finger (C3HC4-type)	18..56	CDD:319650	22/37 (59%)
		Nuclear localization signal. /evidence=ECO:0000255	81..95		8/13 (62%)
		RAWUL_PCGF2	130..228	CDD:340684	36/103 (35%)
		PLN02217	<236..328	CDD:215130	28/167 (17%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	240..344		32/155 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165157900
Domainoid	1	1.000	76	1.000	Domainoid score	I8978
eggNOG	1	0.900	-	-		E1_KOG2660
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000290
OrthoInspector	1	1.000	-	-		otm41753
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	LDO	PTHR10825
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	7	6.840