DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Psc and pcgf2

DIOPT Version :9

Sequence 1:	NP_001286368.1	Gene:	Psc / 36431	FlyBaseID:	FBgn0005624	Length:	1601	Species:	Drosophila melanogaster
Sequence 2:	NP_001025573.1	Gene:	pcgf2 / 594961	XenbaseID:	XB-GENE-1013680	Length:	317	Species:	Xenopus tropicalis

Alignment Length:	404	Identity:	124/404 - (30%)
Similarity:	188/404 - (46%)	Gaps:	107/404 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly   248 RPRPVLLTAVNPHIICHLCQGYLINATTIVECLHSFCHSCLINHLRKERFCPRCEMVINNAKP-- 310
            |...:.:|.:|||::|.||.||.|:|.||||||||||.:|::.:|...:|||.|:..::..:|
Frog     3 RTMRIKMTELNPHLMCALCGGYFIDAATIVECLHSFCKTCILRYLEAHKFCPMCDSQVHKGRPLL 67

  Fly   311 NIKSDTTLQAIVYKLVPGLYERELMRKRAFYK--DRPEEAALATPEQRGDDTEHLIFSPSDDMSL 373
            :|:||.|||.|||||||||:..|:.|:|.||.  .|.::::.|...|:..:.........:::||
Frog    68 SIRSDKTLQDIVYKLVPGLFRDEMKRRRDFYASYSRSKDSSSAEQGQKVLEAGEAPVQEEENISL 132

  Fly   374 SLEYAELGELKTDSEPELVDTLRP---------RYLQCPAMCRVSHLKKFVYDKFEIDAQRFSID 429
            |::::|      |:..|:.|.:..         |:|:|||...::||.||:.:|.::.: ::.::
Frog   133 SIQFSE------DARDEIQDLVDSEDLEKRNSLRFLRCPAAMTITHLAKFLRNKMDVPS-KYKVE 190

  Fly   430 IMYKVKTIVLLDYYTLMDIAYIYTWKRDAPMRFYYRVYESPQPLVKPAPRRVLPLKLEKQERENQ 494
            |:|:.:.  |.||||||||||||.|.|..|:...|||    ||..|       .|:..:
Frog   191 ILYEEEP--LKDYYTLMDIAYIYPWGRTGPLPLKYRV----QPTCK-------RLRFSR------ 236

  Fly   495 EQQLAVEVASSKVEPVSLPEDQKAEASIKVEEQESTREIVKEVIKDVAATPPTETLKLVINRNML 559
                          |.||.:..:...|    |.|||        .|.|::|
Frog   237 --------------PRSLLDFNRGTTS----EGEST--------SDKASSP-------------- 261

  Fly   560 DKREKSHSPQMSSKSSSKSSPCTPVSSPSEPNIKLKIDLSKQNSVTIIDMSDPERREIVKPLKPE 624
                   :| :.|.|||..||.||......||.:|......||.                    .
Frog   262 -------AP-VPSTSSSLPSPATPCQGSPNPNTELPPSSVLQNG--------------------H 298

  Fly   625 KESRSKKKDKDGSP 638
            ..||.:|...:|.|
Frog   299 SASRGRKVALNGVP 312

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Psc	NP_001286368.1	zf-C3HC4	263..301	CDD:278524	22/37 (59%)
Psc	NP_001286368.1	RAWUL	384..465	CDD:292824	31/89 (35%)
pcgf2	NP_001025573.1	RAD18	9..>166	CDD:333230	61/162 (38%)
		RING-HC_PCGF4	12..65	CDD:319650	26/52 (50%)
		RING-HC finger (C3HC4-type)	18..56	CDD:319650	22/37 (59%)
		RAWUL	160..224	CDD:318447	28/66 (42%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	76	1.000	Domainoid score	I8815
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000290
OrthoInspector	1	1.000	-	-		otm48974
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	4.000