DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Psc and SPCC548.05c

DIOPT Version :9

Sequence 1:	NP_001286368.1	Gene:	Psc / 36431	FlyBaseID:	FBgn0005624	Length:	1601	Species:	Drosophila melanogaster
Sequence 2:	NP_587745.1	Gene:	SPCC548.05c / 2539314	PomBaseID:	SPCC548.05c	Length:	468	Species:	Schizosaccharomyces pombe

Alignment Length:	577	Identity:	98/577 - (16%)
Similarity:	190/577 - (32%)	Gaps:	189/577 - (32%)

- Green bases have known domain annotations that are detailed below.

  Fly   208 EDASSNGGASADEEKSE----EDPTAAVAASSTAT---TTSDLATTSRPRPVL---------LTA 256
            ||...|...:.|:||.|    ....:...|||.||   ..|.:::.|..:..:         ...
pombe    14 EDDEENYNNNLDDEKMEVLLIPQSNSTTFASSDATQMYKKSRISSNSENKKQIPDTKTLLETFQK 78

  Fly   257 VNPHIICHLCQGYLINATTIVECLHSFCHSCLINHLRKERFCPRCEMVINNAKPNIKSDTTLQAI 321
            :...:.|.:|...|....| ..|.|::|:.||:|.|::.:.||.|       :..:.:..:...:
pombe    79 IKKTLECPICTEALQRPFT-THCGHTYCYECLLNWLKESKSCPTC-------RQKLYTQPSPAYL 135

  Fly   322 VYKL------------VPGLYERELMRKRAFYKDRPEEAALATPEQRGDDTEHLIFSPSDDMSLS 374
            ||::            :.|:.|....:::....|.                   :|...|.
pombe   136 VYEIMNVVAASNSGFPLVGINENPAKKQKEVLFDG-------------------MFKQEDS---- 177

  Fly   375 LEYAELGELKTDSEPELVDTLRPRY-LQCPAMCRVSHLKKFVYDKFEIDAQRFSIDIMYKVKTIV 438
             .|..  .:..|||..::...|.:: |:.|..|  .|.      .|:|...:
pombe   178 -HYPR--SILVDSEDGVLRCARCQWELENPYHC--DHC------GFQISDDQ------------- 218

  Fly   439 LLDYYTLMDIAYIYTWKRDAPMRFYYRVYESPQPLVKPAPRRVLPLKLEKQERENQEQQLAVEVA 503
                    |....:.|..:                           ..|.....|.:......::
pombe   219 --------DSGREWFWDGE---------------------------NAESDSSLNGDNTRGGNIS 248

  Fly   504 SSKV------EPV-SLPEDQKAEASIKVEEQESTREIVKEVIKDVAATPPTETLKLVINRNMLDK 561
            :::.      .|: ::|:|.     ::.:|.|   |.|...::...:.|.    :..::...:|.
pombe   249 TNRAFNNMGHAPITAVPQDW-----LRFDEGE---EFVGSDLESDFSGPG----EYDVDDGFIDN 301

  Fly   562 REKSHSPQMSSKSSSKSSPCTPVSSPSEPNIKLKIDLSKQNSVTIIDMSDPERREIVKPLKPEKE 626
            |..|   |:|           ||.  |:.:....::.|..|.:|.:|.:|.|..:|:.....|::
pombe   302 RATS---QLS-----------PVE--SDDDFVAPVNGSNGNGITALDSTDSEEIDIMNGFDEERD 350

  Fly   627 -------SRSKKKDKDG-------------------SPKSSSSSSSSSSGERKRKSPSPLTVPPL 665
                   |||:....||                   |..|||::|.|.:....|:.|........
pombe   351 SGGTNMVSRSETCYNDGQRYDELRRELADIQNESLDSLNSSSNNSPSHNNIHSRQHPFSSDEDEG 415

  Fly   666 TIRTERIMSPSGVSTLSPRVTSGAFSEDPKSE-FLKSF----ALKPIKVKVESPERT 717
            .|    :.:.:|:.:......:..|..:|.|| |..|:    |.:...::::|.|.:
pombe   416 NI----VTNGTGLRSSQSSSQNRGFDLEPYSEVFTASYPRRQARRTRTIQLDSDEES 468

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Psc	NP_001286368.1	zf-C3HC4	263..301	CDD:278524	13/37 (35%)
Psc	NP_001286368.1	RAWUL	384..465	CDD:292824	12/81 (15%)
SPCC548.05c	NP_587745.1	RING	84..126	CDD:238093	14/49 (29%)
SPCC548.05c	NP_587745.1	COG2888	<193..213	CDD:268082	5/27 (19%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910