Protein Alignment Mdr49 and ABCB26

DIOPT Version :10

• Sequence 1: NP_523724.2
• Gene: Mdr49 / 36428
• FlyBaseID: FBgn0004512
• Length: 1302
• Species: Drosophila melanogaster
• Sequence 2: NP_177218.3
• Gene: ABCB26 / 843398
• AraportID: AT1G70610
• Length: 700
• Species: Arabidopsis thaliana
• Alignment Length: 553
• Identity: 188/553 - (33%)
• Similarity: 300/553 - (54%)
• Gaps: 55/553 - (9%)

  Fly   766 GDDDVVRAEVLKISMIFVGIGLMAGLGNMLQTYMFTTAGVKMTTRLRKRAFGTIIGQDIAYFDDE 830
            ||..|....|..:..:.|..|:.:|    ::...|..|.:.:..|:|:..:.|::.|||::||.:
plant   170 GDIAVFHRNVKLLVTLCVTSGICSG----IRGCFFGIANMILVKRMRETLYSTLLFQDISFFDSQ 230

  Fly   831 RNSVGALCSRLASDCSNVQGATGARVGTMLQAVATLVVGMVVGFVFSWQQTLLTLVTLPLVCLSV 895
              :||.|.|||.|||..|....|..:..:.:.|......::...:.||...|.|||...::...:
plant   231 --TVGDLTSRLGSDCQQVSRVIGNDLNMIFRNVLQGTGALIYLLILSWPLGLCTLVICCILAAVM 293

  Fly   896 YLEGRFIMKSAQKAKASIEEASQVAVEAITNIRTVNGLCLERQVLDQYVQQIDRV-DIACRRKVR 959
            ::.|.:..|:|:..:.....|::||.|..:.:|||.....|:|...:|...:.|: ||:.|:..
plant   294 FVYGMYQKKTAKLIQEITASANEVAQETYSLMRTVRVYGTEKQEFKRYNHWLQRLADISLRQSA- 357

  Fly   960 FRGLVFALGQAAPFLAYGI------SMYY---------GGILVAEERMNYEDIIK---VAEALIF 1006
                           ||||      ::|:         ||:.:...::..|.:.|   .:|.||:
plant   358 ---------------AYGIWNWSFNTLYHATQIIAVLVGGLSILAGQITAEQLTKFLLYSEWLIY 407

  Fly  1007 GSWMLGQALAYAPNVNDAILSAGRLMDLFKRTSTQPNPPQSPYNT-VEKSEGDIVYENVGFEYPT 1070
            .:|.:|.      |::..:.|.|....:|:....:|:.......| :::..|.|.:.:|.|.||:
plant   408 ATWWVGD------NLSSLMQSVGASEKVFQMMDLKPSDQFISKGTRLQRLTGHIEFVDVSFSYPS 466

  Fly  1071 RKGTPILQGLNLTIKKSTTVALVGPSGSGKSTCVQLLLRYYDPVSGSVNLSGVPSTEFPLDTLRS 1135
            |....::|.:|:::.....||:||.|||||||.|.|||:.|:|.||.:.|.|||..|..:..||.
plant   467 RDEVAVVQNVNISVHPGEVVAIVGLSGSGKSTLVNLLLQLYEPTSGQILLDGVPLKELDVKWLRQ 531

  Fly  1136 KLGLVSQEPVLFDRTIAENIAYGNNFRDDVSMQEIIEAAKKSNIHNFISALPQGYDTRLGKTSQL 1200
            ::|.|.|||.||...|:.||.||.:  .::|.::||.|||::..|:||:|||.||:| :.....|
plant   532 RIGYVGQEPKLFRTDISSNIKYGCD--RNISQEDIISAAKQAYAHDFITALPNGYNT-IVDDDLL 593

  Fly  1201 SGGQKQRIAIARALVRNPKILILDEATSALDLESEKVVQQAL----DEARSGRTCLTIAHRLTTV 1261
            |||||||||||||::|:|:||||||||||||.|||..|:..|    :::.:.|:.:.|||||:|:
plant   594 SGGQKQRIAIARAILRDPRILILDEATSALDAESEHNVKGVLRSIGNDSATKRSVIVIAHRLSTI 658

  Fly  1262 RNADLICVLKRGVVVEHGTHDELMALNKIYANL 1294
            :.||.|..:..|.|||.|:|.||::.:.:||.|
plant   659 QAADRIVAMDSGRVVEMGSHKELLSKDGLYARL 691

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Mdr49	NP_523724.2	MdlB	44..643	CDD:440747
		MdlB	720..1299	CDD:440747	188/553 (34%)
ABCB26	NP_177218.3	MdlB	122..695	CDD:440747	188/553 (34%)