| Sequence 1: | NP_523724.2 | Gene: | Mdr49 / 36428 | FlyBaseID: | FBgn0004512 | Length: | 1302 | Species: | Drosophila melanogaster |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_476831.1 | Gene: | Mdr65 / 38726 | FlyBaseID: | FBgn0004513 | Length: | 1302 | Species: | Drosophila melanogaster |
| Alignment Length: | 1319 | Identity: | 594/1319 - (45%) |
|---|---|---|---|
| Similarity: | 862/1319 - (65%) | Gaps: | 55/1319 - (4%) |
- Green bases have known domain annotations that are detailed below.
|
Fly 4 KEESRLPQAGDFQLKEGSVVDATRKYSYFDLFRYSTRCERFLLVVSLLVATAASAFIPYFMIIYG 68
Fly 69 EFTSLLVDRTVGVGTSSPAFALPMFGGGQQLTNASKEENNQAIIDDATAFGIGSLVGSVAMFLLI 133
Fly 134 TLAIDLANRIALNQIDRIRKLFLEAMLRQDIAWYDTSSGSNFASKMTEDLDKLKEGIGEKIVIVV 198
Fly 199 FLIMTFVIGIVSAFVYGWKLTLVVLSCVPFIIAATSVVARLQGSLAEKELKSYSDAANVVEEVFS 263
Fly 264 GIRTVFAFSGQEKEKERFGKLLIPAENTGRKKGLYSGMGNALSWLIIYLCMALAIWYGVTLILDE 328
Fly 329 RDLPDRVYTPAVLVIVLFAVIMGAQNLGFASPHVEAIAVATAAGQTLFNIIDRPSQVDPMDEKGN 393
Fly 394 RPE-NTAGHIRFEGIRFRYPARPDVEILKGLTVDVLPGQTVAFVGASGCGKSTLIQLMQRFYDPE 457
Fly 458 AGSVKLDGRDLRTLNVGWLRSQIGVVGQEPVLFATTIGENIRYGRPSATQADIEKAARAANCHDF 522
Fly 523 ITRLPKGYDTQVGEKGAQISGGQKQRIAIARALVRQPQVLLLDEATSALDPTSEKRVQSALELAS 587
Fly 588 QGPTTLVVAHRLSTITNADKIVFLKDGVVAEQGTHEELMERRGLYCELVSITQRKEATEADEGAV 652
Fly 653 AGRPLQKSQNLSDE-ETDDDEEDEEEDE----EPELQTSGSSRDSGFRASTR----------RKR 702
Fly 703 RSQRRKKKKDKEVVSKVSFTQLMKLNSPEWRFIVVGGIASVMHGATFPLWGLFFGDFFGILSDGD 767
Fly 768 -DDVVRAEVLKISMIFVGIGLMAGLGNMLQTYMFTTAGVKMTTRLRKRAFGTIIGQDIAYFDDER 831
Fly 832 NSVGALCSRLASDCSNVQGATGARVGTMLQAVATLVVGMVVGFVFSWQQTLLTLVTLPLVCLSVY 896
Fly 897 LEGRFIMKSAQKAKASIEEASQVAVEAITNIRTVNGLCLERQVLDQYVQQIDRVDIACRRKVRFR 961
Fly 962 GLVFALGQAAPFLAYGISMYYGGILVAEERMNYEDIIKVAEALIFGSWMLGQALAYAPNVNDAIL 1026
Fly 1027 SAGRLMDLFKRTSTQPNPPQSPYNTVEKS----EGDIVYENVGFEYPTRKGTPILQGLNLTIKKS 1087
Fly 1088 TTVALVGPSGSGKSTCVQLLLRYYDPVSGSVNLSGVP-STEFPLDTLRSKLGLVSQEPVLFDRTI 1151
Fly 1152 AENIAYGNNFRDDVSMQEIIEAAKKSNIHNFISALPQGYDTRLG-KTSQLSGGQKQRIAIARALV 1215
Fly 1216 RNPKILILDEATSALDLESEKVVQQALDEARSGRTCLTIAHRLTTVRNADLICVLKRGVVVEHGT 1280
Fly 1281 HDELMALNKIYANLYLMQQ 1299 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| Mdr49 | NP_523724.2 | MdlB | 34..640 | CDD:224055 | 295/606 (49%) |
| ABC_membrane | 116..352 | CDD:279056 | 94/235 (40%) | ||
| ABC_MTABC3_MDL1_MDL2 | 402..636 | CDD:213216 | 142/233 (61%) | ||
| MdlB | 735..1299 | CDD:224055 | 272/570 (48%) | ||
| ABC_membrane | 739..998 | CDD:279056 | 96/259 (37%) | ||
| ABC_MTABC3_MDL1_MDL2 | 1059..1298 | CDD:213216 | 151/240 (63%) | ||
| Mdr65 | NP_476831.1 | PTZ00265 | 91..1300 | CDD:240339 | 564/1232 (46%) |
| ABC_membrane | 108..354 | CDD:279056 | 100/245 (41%) | ||
| ABC_MTABC3_MDL1_MDL2 | 405..642 | CDD:213216 | 143/251 (57%) | ||
| ABC_membrane | 736..1006 | CDD:279056 | 103/270 (38%) | ||
| ABC_MTABC3_MDL1_MDL2 | 1059..1299 | CDD:213216 | 151/240 (63%) |
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 0 | 0.000 | Not matched by this tool. | |||
| Domainoid | 1 | 1.000 | 162 | 1.000 | Domainoid score | I1247 |
| eggNOG | 1 | 0.900 | - | - | E2759_KOG0055 | |
| Homologene | 0 | 0.000 | Not matched by this tool. | |||
| Inparanoid | 1 | 1.050 | 156 | 1.000 | Inparanoid score | I209 |
| Isobase | 0 | 0.000 | Not matched by this tool. | |||
| OMA | 1 | 1.010 | - | - | QHG63700 | |
| OrthoDB | 1 | 1.010 | - | - | D186078at2759 | |
| OrthoFinder | 1 | 1.000 | - | - | FOG0000106 | |
| OrthoInspector | 1 | 1.000 | - | - | mtm951 | |
| orthoMCL | 1 | 0.900 | - | - | OOG6_100059 | |
| Panther | 1 | 1.100 | - | - | P | PTHR24221 |
| Phylome | 1 | 0.910 | - | - | ||
| RoundUp | 1 | 1.030 | - | avgDist | Average_Evolutionary_Distance | R932 |
| SonicParanoid | 1 | 1.000 | - | - | X92 | |
| 12 | 11.910 | |||||