Protein Alignment Mdr49 and CG3156

DIOPT Version :9

• Sequence 1: NP_523724.2
• Gene: Mdr49 / 36428
• FlyBaseID: FBgn0004512
• Length: 1302
• Species: Drosophila melanogaster
• Sequence 2: NP_569844.2
• Gene: CG3156 / 30994
• FlyBaseID: FBgn0023536
• Length: 692
• Species: Drosophila melanogaster
• Alignment Length: 605
• Identity: 203/605 - (33%)
• Similarity: 309/605 - (51%)
• Gaps: 63/605 - (10%)

  Fly    67 YGEFTSLLVDR----TVGVG----TSSPAFALPMFGGGQQLTNASKEENNQAIIDDATAFGIGSL 123
            ||...||....    |.|:|    :|:...::|:|     |........|::.:|.|....:|..
  Fly   109 YGRLLSLTKSEKWVLTAGIGCLVVSSAITMSVPLF-----LGKVIDVVFNKSGMDSAAMAKLGEY 168

  Fly   124 VGSVAMFLLITLA-------IDLANRIALNQIDRIRKLFLEAMLRQDIAWYDTSSGSNFASKMTE 181
              ||.:|.:..|.       :.|....||..:..:|.....:||.|::.|:||.......::::.
  Fly   169 --SVLLFGIFVLGGFANFARVHLFGNAALRIVRSLRSRLYRSMLMQEVGWFDTKGTGELINRLSN 231

  Fly   182 DL----DKLKEGIGEKIVIVVFLIMTFVIGIVSAFVYGWKLTLVVLSC--VPFIIAATSVVARLQ 240
            |.    ..|.:.:.:.:..|.      :||:.:..:......|..:|.  ||.:.....|..|..
  Fly   232 DTLMVGTSLSQNVSDGLRSVA------MIGVGTGMMIYTSPQLAAVSALVVPAMAGMAIVYGRYV 290

  Fly   241 GSLAEKELKSYSDAANVVEEVFSGIRTVFAFSGQEKEKERFGKLLIPAENTGRKK--------GL 297
            ..:.:.||..|::.....||.|..::||..|..:::|...|...|..|...|.|:        ||
  Fly   291 RRITKVELDKYAEIMKFAEERFGNVKTVKTFCREQQEVAAFDGKLDEALQIGYKETRARAIFFGL 355

  Fly   298 YSGMGNALSWLIIYLCMALAIWYGVTLILDERDLPDRVYTPAVLVIVLFAVIMGAQNLGFASPHV 362
            ....||.:...::|        ||.||:|.     |.:...|:...:|:|..:.....|.::.:.
  Fly   356 TGFCGNFIIISVLY--------YGGTLVLQ-----DSLTIGALTAFMLYAGYVAISMNGLSNFYS 407

  Fly   363 EAIAVATAAGQTLFNIIDRPSQVDPMDEKGNRP-ENTAGHIRFEGIRFRYPARPDVEILKGLTVD 426
            : :.....|.:.::.|:||...: |:| ||..| |...|.:.|:.:.|.:|.||:..:|...:::
  Fly   408 Q-LNKGIGASERIWEILDRECSI-PID-KGVVPLEKPVGEVGFQNVFFTFPTRPESAVLTDFSLN 469

  Fly   427 VLPGQTVAFVGASGCGKSTLIQLMQRFYDPEAGSVKLDGRDLRTLNVGWLRSQIGVVGQEPVLFA 491
            ::||.|.|.||.||.||:|:..||.|.|||:.|:|.|||.||||:|..|||:.||.|.||||||:
  Fly   470 LMPGTTTAVVGRSGSGKTTIALLMLRLYDPQGGTVHLDGIDLRTVNPQWLRNNIGAVSQEPVLFS 534

  Fly   492 TTIGENIRYG-RPSATQAD--IEKAARAANCHDFITRLPKGYDTQVGEKGAQISGGQKQRIAIAR 553
            .:|.|||.|| .|..|.:.  :::....||...|..:||.|.||.||::|..:|||||||:||||
  Fly   535 CSIRENILYGANPGETPSPERLQQVIEDANVSQFTDQLPDGLDTLVGQRGMMLSGGQKQRVAIAR 599

  Fly   554 ALVRQPQVLLLDEATSALDPTSEKRVQSALELASQGPTTLVVAHRLSTITNADKIVFLKDGVVAE 618
            ||::.|.:|:|||||||||..||..||:||:...||.|.|.:|||||||.|||:|..|.||.:.|
  Fly   600 ALIKNPAILILDEATSALDAVSENLVQNALDNLIQGRTVLTIAHRLSTIRNADQIAVLSDGKIVE 664

  Fly   619 QGTHEELME-RRGLYCELVS 637
            ||::.|||. :.|::.|||:
  Fly   665 QGSYNELMGIQEGVFRELVA 684

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Mdr49	NP_523724.2	MdlB	34..640	CDD:224055	203/605 (34%)
		ABC_membrane	116..352	CDD:279056	55/256 (21%)
		ABC_MTABC3_MDL1_MDL2	402..636	CDD:213216	120/237 (51%)
		MdlB	735..1299	CDD:224055
		ABC_membrane	739..998	CDD:279056
		ABC_MTABC3_MDL1_MDL2	1059..1298	CDD:213216
CG3156	NP_569844.2	MdlB	106..687	CDD:224055	203/605 (34%)
		ABC_membrane	127..395	CDD:279056	63/293 (22%)
		ABC_MTABC3_MDL1_MDL2	447..686	CDD:213216	122/238 (51%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	140	1.000	Domainoid score	I220
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100059
Panther	1	1.100	-	-	P	PTHR24221
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	4	3.910