| Sequence 1: | NP_523724.2 | Gene: | Mdr49 / 36428 | FlyBaseID: | FBgn0004512 | Length: | 1302 | Species: | Drosophila melanogaster |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_036822.1 | Gene: | Abcb4 / 24891 | RGDID: | 620248 | Length: | 1278 | Species: | Rattus norvegicus |
| Alignment Length: | 1311 | Identity: | 557/1311 - (42%) |
|---|---|---|---|
| Similarity: | 809/1311 - (61%) | Gaps: | 79/1311 - (6%) |
- Green bases have known domain annotations that are detailed below.
|
Fly 13 GDFQLKEGSVVDATRK-------YSYFDLFRYSTRCERFLLVVSLLVATAASAFIPYFMIIYGEF 70
Fly 71 TSLLVDRTVGVGTSSPA-FALPMFGGGQQLTNASKEENNQAIIDDATAFGIGSLVGSVAMFLLIT 134
Fly 135 LAIDLANRIALNQIDRIRKLFLEAMLRQDIAWYDTSSGSNFASKMTEDLDKLKEGIGEKIVIVVF 199
Fly 200 LIMTFVIGIVSAFVYGWKLTLVVLSCVPFIIAATSVVARLQGSLAEKELKSYSDAANVVEEVFSG 264
Fly 265 IRTVFAFSGQEKEKERFGKLLIPAENTGRKKGLYSGMGNALSWLIIYLCMALAIWYGVTLILDER 329
Fly 330 DLPDRVYTPAVLVIVLFAVIMGAQNLGFASPHVEAIAVATAAGQTLFNIIDRPSQVDPMDEKGNR 394
Fly 395 PENTAGHIRFEGIRFRYPARPDVEILKGLTVDVLPGQTVAFVGASGCGKSTLIQLMQRFYDPEAG 459
Fly 460 SVKLDGRDLRTLNVGWLRSQIGVVGQEPVLFATTIGENIRYGRPSATQADIEKAARAANCHDFIT 524
Fly 525 RLPKGYDTQVGEKGAQISGGQKQRIAIARALVRQPQVLLLDEATSALDPTSEKRVQSALELASQG 589
Fly 590 PTTLVVAHRLSTITNADKIVFLKDGVVAEQGTHEELMERRGLYCELVSITQRKEATEADEGAVAG 654
Fly 655 RPLQKSQNLSDEETDDDEEDEEEDEEPELQTSGSSRDSG-----FRASTRRKRRSQR-RKKKKDK 713
Fly 714 EV------VSKVSFTQLMKLNSPEWRFIVVGGIASVMHGATFPLWGLFFGDFFGILSDGDDDVVR 772
Fly 773 AEVLKISMIFVGIGLMAGLGNMLQTYMFTTAGVKMTTRLRKRAFGTIIGQDIAYFDDERNSVGAL 837
Fly 838 CSRLASDCSNVQGATGARVGTMLQAVATLVVGMVVGFVFSWQQTLLTLVTLPLVCLSVYLEGRFI 902
Fly 903 MKSAQKAKASIEEASQVAVEAITNIRTVNGLCLERQVLDQYVQQIDRVDIACRRKVRFRGLVFAL 967
Fly 968 GQAAPFLAYGISMYYGGILVAEERMNYEDIIKVAEALIFGSWMLGQALAYAPNVNDAILSAGRLM 1032
Fly 1033 DLFKRTSTQPNPPQSPYNT----VEKSEGDIVYENVGFEYPTRKGTPILQGLNLTIKKSTTVALV 1093
Fly 1094 GPSGSGKSTCVQLLLRYYDPVSGSVNLSGVPSTEFPLDTLRSKLGLVSQEPVLFDRTIAENIAYG 1158
Fly 1159 NNFRDDVSMQEIIEAAKKSNIHNFISALPQGYDTRLG-KTSQLSGGQKQRIAIARALVRNPKILI 1222
Fly 1223 LDEATSALDLESEKVVQQALDEARSGRTCLTIAHRLTTVRNADLICVLKRGVVVEHGTHDELMAL 1287
Fly 1288 NKIYANLYLMQ 1298 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| Mdr49 | NP_523724.2 | MdlB | 34..640 | CDD:224055 | 264/606 (44%) |
| ABC_membrane | 116..352 | CDD:279056 | 82/235 (35%) | ||
| ABC_MTABC3_MDL1_MDL2 | 402..636 | CDD:213216 | 139/233 (60%) | ||
| MdlB | 735..1299 | CDD:224055 | 258/569 (45%) | ||
| ABC_membrane | 739..998 | CDD:279056 | 87/258 (34%) | ||
| ABC_MTABC3_MDL1_MDL2 | 1059..1298 | CDD:213216 | 145/239 (61%) | ||
| Abcb4 | NP_036822.1 | PTZ00265 | 29..1271 | CDD:240339 | 549/1293 (42%) |
| ABC_membrane | 58..342 | CDD:279056 | 102/303 (34%) | ||
| ABC_MTABC3_MDL1_MDL2 | 392..628 | CDD:213216 | 141/247 (57%) | ||
| Interaction with HAX1. /evidence=ECO:0000269|PubMed:15159385 | 622..646 | 10/45 (22%) | |||
| ABC_membrane | 714..984 | CDD:279056 | 91/269 (34%) | ||
| ABC_MTABC3_MDL1_MDL2 | 1033..1272 | CDD:213216 | 145/239 (61%) |
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 0 | 0.000 | Not matched by this tool. | |||
| Domainoid | 1 | 1.000 | 207 | 1.000 | Domainoid score | I2784 |
| eggNOG | 1 | 0.900 | - | - | E2759_KOG0055 | |
| Hieranoid | 1 | 1.000 | - | - | ||
| Homologene | 0 | 0.000 | Not matched by this tool. | |||
| Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
| OMA | 1 | 1.010 | - | - | QHG63700 | |
| OrthoDB | 1 | 1.010 | - | - | D186078at2759 | |
| OrthoFinder | 1 | 1.000 | - | - | FOG0000106 | |
| OrthoInspector | 0 | 0.000 | Not matched by this tool. | |||
| orthoMCL | 1 | 0.900 | - | - | OOG6_100059 | |
| Panther | 0 | 0.000 | Not matched by this tool. | |||
| Phylome | 1 | 0.910 | - | - | ||
| SonicParanoid | 1 | 1.000 | - | - | X92 | |
| SwiftOrtho | 1 | 1.000 | - | - | ||
| TreeFam | 0 | 0.000 | Not matched by this tool. | |||
| 10 | 9.730 | |||||