| Sequence 1: | NP_523724.2 | Gene: | Mdr49 / 36428 | FlyBaseID: | FBgn0004512 | Length: | 1302 | Species: | Drosophila melanogaster |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_510126.1 | Gene: | pgp-12 / 181415 | WormBaseID: | WBGene00004006 | Length: | 1318 | Species: | Caenorhabditis elegans |
| Alignment Length: | 1356 | Identity: | 457/1356 - (33%) |
|---|---|---|---|
| Similarity: | 730/1356 - (53%) | Gaps: | 146/1356 - (10%) |
- Green bases have known domain annotations that are detailed below.
|
Fly 5 EESRLPQAGDFQLKEGSVVDATRKYS-----YFDLFRYSTRCERFLLVVSLLVATAASAFIPYFM 64
Fly 65 IIYGEFTSLLVDRTVGVGTSSPAFALPMFGGGQQLTNASKEENNQAIIDDATAF-GIGSLVGSVA 128
Fly 129 MFLLITLAIDLANRIALNQI-DRIRKLFLEAMLRQDIAWYDTSSGSNFASKMTEDLDKLKEGIGE 192
Fly 193 KIVIVVFLIMTFVIGIVSAFVYGWKLTLVVLSCVPFIIAATSVVARLQGSLAEKELKSYSDAANV 257
Fly 258 VEEVFSGIRTVFAFSGQEKEKERFGKLLIPAENTGRKKGLYSGMGNALSWLIIYLCMALAIWYGV 322
Fly 323 TLILDERDLPDR---VYTPAVLVIVLFAVIMGAQNLGFASPHVEAIAVATAAGQTLFNIIDRPSQ 384
Fly 385 VDPMDEKGNRPENTAGHIRFEGIRFRYPARPDVEILKGLTVDVLPGQTVAFVGASGCGKSTLIQL 449
Fly 450 MQRFYDPEAGSVKLDGRDLRTLNVGWLRSQIGVVGQEPVLFATTIGENIRYGRPSATQADIEKAA 514
Fly 515 RAANCHDFITRLPKGYDTQVGEKGAQISGGQKQRIAIARALVRQPQVLLLDEATSALDPTSEKRV 579
Fly 580 QSALELASQGPTTLVVAHRLSTITNADKIVFLKDGVVAEQGTHEELMERRGLYCELVSITQRKEA 644
Fly 645 TEADEGAVAGRPLQKSQNLSDEETDDDEEDEEEDEEPELQTSG-----SSRDSGFRAS------- 697
Fly 698 -----------TRRKRRSQRRKKKKD-KEVVSKV---------SFTQLMKLNSPEWRFIVVGGIA 741
Fly 742 SVMHGATFPLWGLFFGDFFGILSDGDDDVVRAEVLKISMIFVGIGLMAGLGNMLQTYMFTTAGVK 806
Fly 807 MTTRLRKRAFGTIIGQDIAYFDDERNSVGALCSRLASDCSNVQGATGARVGTMLQAVATLVVGMV 871
Fly 872 VGFVFSWQ----QTLLTLVTLPLVCLSVYLEGRFIMKSAQKAKASIEEASQVAVEAITNIRTVNG 932
Fly 933 LCLERQVLDQY-----VQQIDRVDIACRRKVRFRGLVFALGQA----APFLAYGIS--MYYGGIL 986
Fly 987 VAEERMNYEDIIKVAEALIFGSWMLGQALAYAPNVNDAILSAGRLMDLFKRTSTQPNPPQSPYNT 1051
Fly 1052 VEKSEGDIVYENVGFEYPTRKGTPILQGLNLTIKKSTTVALVGPSGSGKSTCVQLLLRYYDPVSG 1116
Fly 1117 SVNLSGVPSTEFPLDTLRSKLGLVSQEPVLFDRTIAENIAYGNNFRDDVSMQEIIEAAKKSNIHN 1181
Fly 1182 FISALPQGYDTRLG-KTSQLSGGQKQRIAIARALVRNPKILILDEATSALDLESEKVVQQALDEA 1245
Fly 1246 RSGRTCLTIAHRLTTVRNADLICVLKRGVVVEHGTHDELMALNKIYANLYLMQQVS 1301 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| Mdr49 | NP_523724.2 | MdlB | 34..640 | CDD:224055 | 227/610 (37%) |
| ABC_membrane | 116..352 | CDD:279056 | 63/240 (26%) | ||
| ABC_MTABC3_MDL1_MDL2 | 402..636 | CDD:213216 | 129/233 (55%) | ||
| MdlB | 735..1299 | CDD:224055 | 200/579 (35%) | ||
| ABC_membrane | 739..998 | CDD:279056 | 63/273 (23%) | ||
| ABC_MTABC3_MDL1_MDL2 | 1059..1298 | CDD:213216 | 122/239 (51%) | ||
| pgp-12 | NP_510126.1 | ABC_membrane | 97..332 | CDD:279056 | 62/263 (24%) |
| PTZ00265 | 145..1312 | CDD:240339 | 432/1228 (35%) | ||
| ABC_MTABC3_MDL1_MDL2 | 417..654 | CDD:213216 | 131/236 (56%) | ||
| ABC_membrane | 762..1005 | CDD:294371 | 58/253 (23%) | ||
| ABC_MTABC3_MDL1_MDL2 | 1077..1314 | CDD:213216 | 122/239 (51%) |
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 0 | 0.000 | Not matched by this tool. | |||
| Domainoid | 1 | 1.000 | 60 | 1.000 | Domainoid score | I7003 |
| eggNOG | 1 | 0.900 | - | - | E2759_KOG0055 | |
| Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
| Homologene | 0 | 0.000 | Not matched by this tool. | |||
| Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
| Isobase | 0 | 0.000 | Not matched by this tool. | |||
| OMA | 1 | 1.010 | - | - | QHG63700 | |
| OrthoDB | 1 | 1.010 | - | - | D186078at2759 | |
| OrthoFinder | 1 | 1.000 | - | - | FOG0000106 | |
| OrthoInspector | 0 | 0.000 | Not matched by this tool. | |||
| orthoMCL | 1 | 0.900 | - | - | OOG6_100059 | |
| Panther | 1 | 1.100 | - | - | O | PTHR24221 |
| Phylome | 1 | 0.910 | - | - | ||
| RoundUp | 0 | 0.000 | Not matched by this tool. | |||
| SonicParanoid | 1 | 1.000 | - | - | X92 | |
| SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
| TreeFam | 1 | 0.960 | - | - | ||
| 10 | 9.790 | |||||