Protein Alignment Sans and AKR2

DIOPT Version :10

• Sequence 1: NP_610829.1
• Gene: Sans / 36427
• FlyBaseID: FBgn0033785
• Length: 516
• Species: Drosophila melanogaster
• Sequence 2: NP_014677.1
• Gene: AKR2 / 854199
• SGDID: S000005560
• Length: 749
• Species: Saccharomyces cerevisiae
• Alignment Length: 270
• Identity: 64/270 - (23%)
• Similarity: 100/270 - (37%)
• Gaps: 88/270 - (32%)

  Fly     4 DRFHKAAKDGLLDVLAAATRK---DTNAKDSDSMTPVMWAAFEGRLDALRLLCGRGGDPDK-CDQ 64
            |.|.:|||||.|.|:......   |.|....|.::.:.||....|....:.|..||.:|:: ...
Yeast    52 DIFIEAAKDGDLKVVKDVVESGAVDINNDRIDELSGLHWACINNRFSVAKFLLLRGANPNQAAGP 116

  Fly    65 FGNTALHLASAKGHLHCVDFLVKFGVN------------------------IYAL---------- 95
            .|.||||.|:..|:::.||.|:|.|.:                        :|.|
Yeast   117 GGATALHWAARYGNIYIVDLLLKHGADPTLKDEQGLNIMHFSVYSSNILLVVYVLYFVVNNNDNV 181

  Fly    96 DIDKHSAKD--------LAAINGRDEILRYLDVAFTNFEA-TEKKKSKALKELAEKNC-----EK 146
            |||   :||        .||..| |.:...|.:.|.:..| |:.:...||      :|     ::
Yeast   182 DID---SKDNNNRTPLLWAAYQG-DFLTVELLLKFGSTVAWTDNRGFNAL------HCALVGGDQ 236

  Fly   147 RV--------REYMKRQNQQQQRQDPEYSDLSAPSGS-------------SKTGNMLSTLKQKIW 190
            ||        ..:.:|.||:|     :..||:...|:             .:.||....|.:|..
Yeast   237 RVICDLILSGANFYERNNQKQ-----DCFDLAEGMGTKSLFEQALQHHGYDRLGNQKDKLFKKSS 296

  Fly   191 SSQGNLNKTP 200
            .:|..:..:|
Yeast   297 HAQFTIFLSP 306

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sans	NP_610829.1	ANKYR	<6..>118	CDD:440430	41/157 (26%)
		ANK repeat	35..63	CDD:293786	7/28 (25%)
		ANK repeat	65..96	CDD:293786	14/64 (22%)
		SAM_USH1G_HARP	443..508	CDD:188916
AKR2	NP_014677.1	ANKYR	6..292	CDD:440430	60/254 (24%)
		ANK repeat	54..81	CDD:293786	10/26 (38%)
		ANK repeat	83..115	CDD:293786	8/31 (26%)
		ANK repeat	117..148	CDD:293786	12/30 (40%)
		ANK repeat	189..220	CDD:293786	7/31 (23%)
		ANK repeat	222..247	CDD:293786	5/30 (17%)
		COG5273	340..711	CDD:227598