DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG17019 and APD3

DIOPT Version :9

Sequence 1:	NP_001286365.1	Gene:	CG17019 / 36425	FlyBaseID:	FBgn0033783	Length:	700	Species:	Drosophila melanogaster
Sequence 2:	NP_181357.2	Gene:	APD3 / 818401	AraportID:	AT2G38220	Length:	404	Species:	Arabidopsis thaliana

Alignment Length:	382	Identity:	89/382 - (23%)
Similarity:	146/382 - (38%)	Gaps:	72/382 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly   350 EAVEETPTTSAADEILEVTLRSRPAVEGDDSEMGESTQALNVNQRPANPSPAFYPAVPQRTKKVT 414
            |.|...|.:|...:...:.::|....|.|.|:.|......|   ..:.||..|......|...|:
plant    64 ETVWLGPNSSILVKPSSIFVKSIKVKELDFSKPGLQLYGFN---GQSTPSGYFVNWTESRVLSVS 125

  Fly   415 RRRSDG---YLNRRYHSSDDESPVAPGGPGLSLGLSTLSEHPEHGLHPHSHRQSCQRCGKNKT-- 474
            :....|   ||||..|.:...: :.|.|..:.|.::..|:  ..|: |..:|.|.:......|
plant   126 QNSYKGWPYYLNRGTHMNISYN-ILPKGSAVRLVITEGSQ--VIGM-PFFYRSSLKDIAFRDTAW 186

  Fly   475 --NIRRHVEKMRRHLENSQMSEEDIKRELQEFLTYLEQRTKSVDAS-DADSHAV----SPLSVDA 532
              |:          ::.|.|.:.||.:....:||....:.|.::.. |.|..||    ...|.:.
plant   187 SWNL----------IQGSGMIQLDISKSKGYYLTVANLKRKDIEVELDIDVKAVLYDTKQTSYNC 241

  Fly   533 ISVAAGGRSPDM----PI-TPTIEFSPTQDEDIRWDDDEGIHVYAAPSDFEPTAGIDSRFVNLED 592
             |.:.|..|..|    |: ...:..||...:.:..||:..|.:     .::|      |.:....
plant   242 -SFSNGECSFKMNERYPVENYAVVTSPALGQGVSIDDEWYIEL-----SYQP------RLIAYGS 294

  Fly   593 FEDLKDLEGLTVKQLKEVLMLHRVDYKGCCEKQELLDRVSRLWKTMRECPAVEKLATD------- 650
            |      .|:.:..:  ::.:|..:...||..:..|....    ::|.|...:|...|
plant   295 F------TGVLLSFM--LVAIHFCNKLKCCGGEGFLSGDD----SVRTCLLADKGDNDCCNDVEA 347

  Fly   651 ---ELCKICMDAPIECVFLECGHMATCTSCG----KVLNECPICRQYIVRVVRFFRA 700
               .||.||.|||.:|.||.|||..:|..||    :....|||||:.::.|.|.:.|
plant   348 SNKSLCAICFDAPRDCCFLPCGHCVSCYQCGTKIKRTKGRCPICRKKMIHVKRIYTA 404

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG17019	NP_001286365.1	FYVE_CARP	1..42	CDD:277289
CG17019	NP_001286365.1	zf-C3HC4_3	650..694	CDD:290631	22/57 (39%)
APD3	NP_181357.2	DUF4792	98..164	CDD:374322	15/69 (22%)
		DUF4793	196..306	CDD:374323	25/129 (19%)
		zf-C3HC4_3	349..394	CDD:372816	21/44 (48%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	53	1.000	Domainoid score	I4202
eggNOG	1	0.900	-	-		E1_KOG4275
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1361306at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm3123
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.820