DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment sug and CMR3

DIOPT Version :9

Sequence 1:	NP_610826.1	Gene:	sug / 36424	FlyBaseID:	FBgn0033782	Length:	384	Species:	Drosophila melanogaster
Sequence 2:	NP_015338.1	Gene:	CMR3 / 856123	SGDID:	S000006217	Length:	317	Species:	Saccharomyces cerevisiae

Alignment Length:	295	Identity:	59/295 - (20%)
Similarity:	104/295 - (35%)	Gaps:	94/295 - (31%)

- Green bases have known domain annotations that are detailed below.

  Fly    10 NSGPHSRGIYE------PPLGYFTP---YNTPPYIAA----------------------YSD-SG 42
            ||..:.|..|.      ||:....|   .||||.:.:                      |:. |.
Yeast    58 NSYKNERECYNSTKINLPPISSLLPNFENNTPPNVDSRVQFPPQQVYQSMNVVPIVNEIYTPISM 122

  Fly    43 SWLADHHQHHQQQHQQ---HQQQMQHIRFPTP---PITPP---RPIAGYGYRQRTQSVIMKARGQ 98
            :..:|.:..:..:.||   |.|. .|:....|   |:..|   :|:..|.
Yeast   123 NATSDQYPIYYTESQQPIPHSQS-PHLTSSAPLMMPVMVPTVYKPLTPYD--------------- 171

  Fly    99 QDELCRSPVEFPDDSK--SCSSSSECGTASDFVCNWTDCDR---------VFDTLDALAQHVTQR 152
                 :.|:....:..  :.|.:|....|.: :|:    ||         |..|:...:...|:.
Yeast   172 -----KEPITIASEPNFTAISMASHPNAALE-LCH----DRPKSVPPGYGVLPTMQEASNGRTKS 226

  Fly   153 HAIASLTDGLYYCRWRGCQRSERGFNARYKMLVHTRTHTKEKPHRCHLCEKSFSRAENLKIHIRS 217
            ...|.|.....:..|:                ..||..:.:...:|.:|.|..||...||.|...
Yeast   227 EPGAVLNGSATFSDWK----------------TDTRISSTKLRKQCPVCGKICSRPSTLKTHYLI 275

  Fly   218 HSGEKPYKCSFEGCQKAYSNSSDRFKHTRTHSMEK 252
            |:|:.|:||::|||.|:::..|:..:|.::|..::
Yeast   276 HTGDTPFKCTWEGCTKSFNVKSNMLRHLKSHERKR 310

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
sug	NP_610826.1	C2H2 Zn finger	170..190	CDD:275368	2/19 (11%)
		zf-H2C2_2	183..207	CDD:290200	5/23 (22%)
		COG5048	192..>271	CDD:227381	20/61 (33%)
		C2H2 Zn finger	198..218	CDD:275368	8/19 (42%)
		zf-H2C2_2	210..237	CDD:290200	12/26 (46%)
		C2H2 Zn finger	226..248	CDD:275368	7/21 (33%)
		C2H2 Zn finger	256..277	CDD:275368
CMR3	NP_015338.1	COG5048	17..316	CDD:227381	59/295 (20%)
		C2H2 Zn finger	256..276	CDD:275370	8/19 (42%)
		C2H2 Zn finger	284..306	CDD:275370	7/21 (33%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	54	1.000	Inparanoid score	I1809
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.050