DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment sug and zic2a

DIOPT Version :9

Sequence 1:	NP_610826.1	Gene:	sug / 36424	FlyBaseID:	FBgn0033782	Length:	384	Species:	Drosophila melanogaster
Sequence 2:	NP_571633.1	Gene:	zic2a / 58077	ZFINID:	ZDB-GENE-000710-4	Length:	445	Species:	Danio rerio

Alignment Length:	347	Identity:	110/347 - (31%)
Similarity:	149/347 - (42%)	Gaps:	99/347 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly    31 TPPYIAA--YSDSGSW-------LADHHQHHQQQHQQHQQQMQHIRFPTPPITPPRPIAGYGYRQ 86
            |.||.||  ::..||.       :|.||.|                          |.|.:.| .
Zfish   178 TDPYSAAQLHNQYGSMNMNMGMNMAAHHHH--------------------------PGAFFRY-M 215

  Fly    87 RTQSVIMKARGQQDELCR--SPVEFPDDSKSCSSSSECGTASDFVCNWTDCDRVFDTLDALAQHV 149
            |.|.:      :|:.:|:  .|.:..:..||                   |::.|.|:..|..||
Zfish   216 RQQCI------KQELICKWIDPEQLSNPKKS-------------------CNKTFSTMHELVTHV 255

  Fly   150 TQRHAIASLTDGLYYCRWRGCQRSERGFNARYKMLVHTRTHTKEKPHRCHL--CEKSFSRAENLK 212
            :..| :.......:.|.|..|.|..:.|.|:||::.|.|.||.|||..|..  |.|.|:|:||||
Zfish   256 SVEH-VGGPEQSNHICFWEECPRESKPFKAKYKLVNHIRVHTGEKPFPCPFPGCGKVFARSENLK 319

  Fly   213 IHIRSHSGEKPYKCSFEGCQKAYSNSSDRFKHTRTHSMEKPYMCKVAGCQKRYTDPSSLRKHVKT 277
            ||.|:|:||||::|.||||.:.::|||||.||...|:.:|||:||:  |.|.||.|||||||:|
Zfish   320 IHKRTHTGEKPFQCEFEGCDRRFANSSDRKKHMHVHTSDKPYLCKM--CDKSYTHPSSLRKHMK- 381

  Fly   278 FKHSIHLIASQPLTLPSVPCLLEASSESAFTCLPAASSVESTSSSSSARYYDDSNNEPSDYSLKP 342
                :|                 .||..|....|||||  ...||:.......|....|:.:|.|
Zfish   382 ----VH-----------------ESSPPASDSSPAASS--GYESSTPPGLVSPSTETQSNNNLSP 423

  Fly   343 KQDAEFSPSYWLGDRQHSYLHS 364
            ......|       ..||.|.|
Zfish   424 SSAVHSS-------NNHSSLSS 438

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
sug	NP_610826.1	C2H2 Zn finger	170..190	CDD:275368	8/19 (42%)
		zf-H2C2_2	183..207	CDD:290200	11/25 (44%)
		COG5048	192..>271	CDD:227381	44/80 (55%)
		C2H2 Zn finger	198..218	CDD:275368	12/21 (57%)
		zf-H2C2_2	210..237	CDD:290200	16/26 (62%)
		C2H2 Zn finger	226..248	CDD:275368	12/21 (57%)
		C2H2 Zn finger	256..277	CDD:275368	13/20 (65%)
zic2a	NP_571633.1	C2H2 Zn finger	275..295	CDD:275368	8/19 (42%)
		zf-H2C2_2	288..314	CDD:290200	11/25 (44%)
		C2H2 Zn finger	303..325	CDD:275368	12/21 (57%)
		zf-H2C2_2	317..344	CDD:290200	16/26 (62%)
		C2H2 Zn finger	333..355	CDD:275368	12/21 (57%)
		zf-C2H2	361..383	CDD:278523	15/28 (54%)
		C2H2 Zn finger	363..383	CDD:275368	14/26 (54%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X217
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.910