DRSC/TRiP Functional Genomics Resources

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Protein Alignment sug and glis3

DIOPT Version :9

Sequence 1:NP_610826.1 Gene:sug / 36424 FlyBaseID:FBgn0033782 Length:384 Species:Drosophila melanogaster
Sequence 2:XP_017213470.1 Gene:glis3 / 571000 ZFINID:ZDB-GENE-070112-2232 Length:804 Species:Danio rerio


Alignment Length:328 Identity:122/328 - (37%)
Similarity:170/328 - (51%) Gaps:46/328 - (14%)


- Green bases have known domain annotations that are detailed below.


  Fly    54 QQHQQHQQQMQHIRFPTPPITPPRPIAGYGYRQRTQSVIMKAR--GQQDELCRSPVEFPDDSKSC 116
            |.|....:..:.:|.|:||..||.|.:.:..:|:...|:...|  |.|..|    .|..::.:||
Zfish   336 QTHTLQFEVSRIVRSPSPPRGPPPPYSAHHQQQQQPRVLQLQRPAGLQPML----EEEEEEEESC 396

  Fly   117 SSSSECGTASDFVCNWTDCDRVFDTLDALAQHVTQRHAIASLTDGLYYCRWRGCQRSERGFNARY 181
             ..:.|       |.|..|..::...|||.:|:.:.|......:. :.|.|.||.|..:.|||||
Zfish   397 -GGTHC-------CCWLHCGAIYSHRDALVKHIEKIHVDQRKGED-FTCFWAGCARKHKPFNARY 452

  Fly   182 KMLVHTRTHTKEKPHRCHL--CEKSFSRAENLKIHIRSHSGEKPYKCSFEGCQKAYSNSSDRFKH 244
            |:|:|.|.|:.|||::|..  |:|:|||.||||||:|||:|||||.|...||.||:||||||.||
Zfish   453 KLLIHMRVHSGEKPNKCSFEGCQKAFSRLENLKIHLRSHTGEKPYVCPHPGCLKAFSNSSDRAKH 517

  Fly   245 TRTHSMEKPYMCKVAGCQKRYTDPSSLRKHVKTFKHSI-HLIASQPLTLPSVPCLLEASSESAFT 308
            .|||...|||.|::.||.||||||||||||||:  ||: ...|.:.|...|     :.|.:....
Zfish   518 QRTHVDTKPYACQIQGCGKRYTDPSSLRKHVKS--HSLKEQQARKKLRRSS-----DLSQDGLSE 575

  Fly   309 CL---PAASSVESTSSSSSARYYDDSN--------NEPSDYSL--KPKQDAEFSPSYWLGDRQHS 360
            ||   |...|: ||.....::::..::        |:||..:.  .|.|.|.       |.:.|.
Zfish   576 CLTVQPLQHSL-STLDLIESKHHSPTDDLYTVFTLNQPSQTNTLNSPMQIAG-------GPQTHQ 632

  Fly   361 YLH 363
            ..|
Zfish   633 SPH 635

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
sugNP_610826.1 C2H2 Zn finger 170..190 CDD:275368 11/19 (58%)
zf-H2C2_2 183..207 CDD:290200 11/25 (44%)
COG5048 192..>271 CDD:227381 52/80 (65%)
C2H2 Zn finger 198..218 CDD:275368 13/21 (62%)
zf-H2C2_2 210..237 CDD:290200 18/26 (69%)
C2H2 Zn finger 226..248 CDD:275368 14/21 (67%)
C2H2 Zn finger 256..277 CDD:275368 16/20 (80%)
glis3XP_017213470.1 None


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 1 1.000 - -
TreeFam 00.000 Not matched by this tool.
ZFIN 00.000 Not matched by this tool.
21.910

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