DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment sug and zic6

DIOPT Version :9

Sequence 1:	NP_610826.1	Gene:	sug / 36424	FlyBaseID:	FBgn0033782	Length:	384	Species:	Drosophila melanogaster
Sequence 2:	NP_001001837.1	Gene:	zic6 / 415097	ZFINID:	ZDB-GENE-061207-1	Length:	525	Species:	Danio rerio

Alignment Length:	339	Identity:	115/339 - (33%)
Similarity:	159/339 - (46%)	Gaps:	88/339 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly    77 RPIAGYGYRQRTQSVIMK------------ARGQQDELCRSPVEFPDDSKSCSSSSECGTASDFV 129
            :|::  |.|..:|.::.:            .||..|...|           ||..:   ...:.|
Zfish   172 QPVS--GPRANSQQLVTQFLEFYKPLNMAMQRGGGDAFLR-----------CSRQN---PKHELV 220

  Fly   130 CNWTD---------CDRVFDTLDALAQHVTQRHAIASLTDGLYYCRWRGCQRSERGFNARYKMLV 185
            |.|:|         |.|.|.|:..|..|||..| :.......|.|.|..|.|..:.|.|:||::.
Zfish   221 CKWSDGQEGTGKPPCARSFGTMYELVTHVTVEH-VGGPEHSDYVCHWENCPRDRKPFKAKYKLVN 284

  Fly   186 HTRTHTKEKPHRC--HLCEKSFSRAENLKIHIRSHSGEKPYKCSFEGCQKAYSNSSDRFKHTRTH 248
            |.|.||.|||..|  |.|||.|:|:||||||.|:|:||||:||.||||.:.::|||||.||:..|
Zfish   285 HVRVHTGEKPFPCPFHGCEKVFARSENLKIHKRTHTGEKPFKCEFEGCNRRFANSSDRKKHSHVH 349

  Fly   249 SMEKPYMCKVAGCQKRYTDPSSLRKHVKTF---------KHSIHLIASQPLTLPSVPCLLEASSE 304
            |.:|||.|||.||:|.||.|||||||:|..         :...||:.::.   |.|       :|
Zfish   350 SSDKPYTCKVRGCEKCYTHPSSLRKHMKLHCKAYIAKIGEDDEHLVEARS---PEV-------TE 404

  Fly   305 SAFTCLPAASSVESTSSSSSARYYDDSNNEPSDYSLKPKQDAEFSPSYWLGDRQHSYLHSEDFFV 369
            ...|  ||:::|..|.::            ||..:|.|:...|.:    :..|.|   |:
Zfish   405 HQDT--PASTTVTRTMTT------------PSHETLSPETRNESA----VRSRFH---HT----- 443

  Fly   370 KMDVESPLDLRIHR 383
               .|:.||...||
Zfish   444 ---FENTLDYTAHR 454

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
sug	NP_610826.1	C2H2 Zn finger	170..190	CDD:275368	8/19 (42%)
		zf-H2C2_2	183..207	CDD:290200	13/25 (52%)
		COG5048	192..>271	CDD:227381	50/80 (63%)
		C2H2 Zn finger	198..218	CDD:275368	14/21 (67%)
		zf-H2C2_2	210..237	CDD:290200	17/26 (65%)
		C2H2 Zn finger	226..248	CDD:275368	12/21 (57%)
		C2H2 Zn finger	256..277	CDD:275368	15/20 (75%)
zic6	NP_001001837.1	C2H2 Zn finger	269..289	CDD:275368	8/19 (42%)
		zf-H2C2_2	282..308	CDD:290200	13/25 (52%)
		C2H2 Zn finger	297..319	CDD:275368	14/21 (67%)
		zf-H2C2_2	311..338	CDD:290200	17/26 (65%)
		C2H2 Zn finger	327..349	CDD:275368	12/21 (57%)
		C2H2 Zn finger	357..379	CDD:275368	16/21 (76%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X217
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.910