DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment sug and CG14655

DIOPT Version :9

Sequence 1:NP_610826.1 Gene:sug / 36424 FlyBaseID:FBgn0033782 Length:384 Species:Drosophila melanogaster
Sequence 2:NP_649494.1 Gene:CG14655 / 40594 FlyBaseID:FBgn0037275 Length:525 Species:Drosophila melanogaster


Alignment Length:384 Identity:87/384 - (22%)
Similarity:147/384 - (38%) Gaps:90/384 - (23%)


- Green bases have known domain annotations that are detailed below.


  Fly    21 PPLGYFTPYNTPPY---IAAYSDSGSWLADHH---QHHQQQHQQHQQQMQHIRFPTPPITPPR-P 78
            ||:     ..|||.   |..:|...:.|.|.|   .|...:.:..|::.|.   ..|...|.: .
  Fly   104 PPV-----RTTPPAHCDICEFSFRNTELRDMHVRLVHENAEGEPKQKEPQQ---KEPDQEPYKCH 160

  Fly    79 IAGYGYRQR-TQSVIMKARGQQDELCRSPVEFPDDSKSCSSSSECGTASDFVCNWTDCDRVFDT- 141
            :....:|.: :..:.:|........|.:|...|:.|.:.:|::...||:.   ..:.|||:..| 
  Fly   161 LCSKTFRMKGSLRIHLKVVHMMGVPCSNPNPNPNPSPTPASTTSAVTATP---KLSICDRIRHTE 222

  Fly   142 -----------------------LDALAQHVTQRHAIASLTDGLYYCRWRGCQRSERGFNARYKM 183
                                   |..|.|..:...: .:.|..|:.|  ..|.:|   |..:|.:
  Fly   223 PGALGNGNNSTCTASQPYALSGALSMLQQSPSSPES-GTATPKLWEC--DVCSKS---FTTKYFL 281

  Fly   184 LVHTRTHTKEKPHRCHLCEKSFSRAENLKIHIRSHSGEKPYKCSFEGCQKAYSNSSDRFKHTRTH 248
            ..|.|.||.|.|:.|.:|.::|:..::...|:..||..||:.|..  |.:|:...|....|.|.|
  Fly   282 KKHKRLHTGEMPYTCEICARTFTFQQSYHKHLLYHSEVKPHVCGV--CGRAFKELSTLHNHQRIH 344

  Fly   249 SMEKPYMCKVAGCQKRYTDPSSLRKHV---------------KTFKHSI----HLIASQPLTLPS 294
            |.|||:.|:|  |.|.:....|...|.               |||::.:    |...::....|.
  Fly   345 SGEKPFKCEV--CGKCFRQRVSFLVHTRIHTGVMPYKCELCQKTFRYKVSQRTHRCPTEEAQTPE 407

  Fly   295 --VPCLLEASSESAFTCLPAASSVESTSSSSSARYYDDSNNEPSDYSLKPKQDAEFSPS 351
              :...|| .::|.....||::.:.:.:|||               .:.|:|:|..|.|
  Fly   408 QLIKAFLE-GNDSHTQPSPASAEIAAINSSS---------------IVDPEQEALLSQS 450

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
sugNP_610826.1 C2H2 Zn finger 170..190 CDD:275368 6/19 (32%)
zf-H2C2_2 183..207 CDD:290200 9/23 (39%)
COG5048 192..>271 CDD:227381 25/78 (32%)
C2H2 Zn finger 198..218 CDD:275368 4/19 (21%)
zf-H2C2_2 210..237 CDD:290200 8/26 (31%)
C2H2 Zn finger 226..248 CDD:275368 6/21 (29%)
C2H2 Zn finger 256..277 CDD:275368 6/35 (17%)
CG14655NP_649494.1 C2H2 Zn finger 268..288 CDD:275368 7/24 (29%)
zf-H2C2_2 281..304 CDD:290200 8/22 (36%)
C2H2 Zn finger 324..344 CDD:275368 6/21 (29%)
zf-H2C2_2 339..361 CDD:290200 11/23 (48%)
C2H2 Zn finger 352..372 CDD:275368 6/21 (29%)
zf-H2C2_2 364..389 CDD:290200 5/24 (21%)
C2H2 Zn finger 380..396 CDD:275368 3/15 (20%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 1 1.050 54 1.000 Inparanoid score I1809
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
11.050

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