Protein Alignment sug and gli3

DIOPT Version :10

• Sequence 1: NP_610826.1
• Gene: sug / 36424
• FlyBaseID: FBgn0033782
• Length: 384
• Species: Drosophila melanogaster
• Sequence 2: NP_991291.1
• Gene: gli3 / 403042
• ZFINID: ZDB-GENE-041111-162
• Length: 1553
• Species: Danio rerio
• Alignment Length: 596
• Identity: 146/596 - (24%)
• Similarity: 193/596 - (32%)
• Gaps: 257/596 - (43%)

  Fly     7 SIFNSGPHSRGIYEPPLGYFTPYN-TPPYIAAYSD-----------------SGSWLADHHQ--- 50
            |:....||.    .|.:|..:|:| :.|||..|.|                 .|...||.|.
Zfish   173 SLIRISPHR----NPSMGTDSPFNPSHPYINPYMDYIRSLHSSPSLSMVSAARGLSPADTHHTGL 233

  Fly    51 -----HHQQQ---------------------------HQQHQQQMQHIRFPTP----------PI 73
                 :||..                           |.::.|.|:..|||:|          ||
Zfish   234 TTAEYYHQMALLVGHRSPYADLIPSVGSTTGPASSALHMEYLQAMESSRFPSPRLINRPSRKRPI 298

  Fly    74 T--------------------------------------------------------PPRPIAGY 82
            .                                                        ||.|:|..
Zfish   299 PNSPSLSDPSFDLQAMIRTSPNSLVTILNNSRSSSSNSGSYGHLSAGTISPALSFAYPPTPVALQ 363

  Fly    83 GYRQ---RTQSVIMKARGQQDELCRSPVEF---------------PDDSKSCSSSSECGTASDFV 129
            .::|   |...::..|.|....|..|.:.|               |.:....|:.|:....|:..
Zfish   364 MHQQLISRQPGIVGSAFGHSPPLMHSALAFSTQRPVPAIQTSSLAPTERSIVSNDSQSKPTSESA 428

  Fly   130 -----------------------------------------------------------CNWTDC 135
                                                                       |:|..|
Zfish   429 VSSTGDPMNHKRSKLKPEEEPPSPRAVSMQEQMNGMTLVKEEGDKEEGKQEPEVVYETNCHWDGC 493

  Fly   136 DRVFDTLDALAQHVTQRHAIASLTDGLYYCRWRGCQRSERGFNARYKMLVHTRTHTKEKPHRCHL 200
            .|.|||.:.|..|:...|......:  :.|||..|.|.::.|.|:|.::||.|.||.||||:|..
Zfish   494 CREFDTQEQLVHHINNDHIHGEKKE--FVCRWEECSREQKPFKAQYMLVVHMRRHTGEKPHKCTF 556

  Fly   201 --CEKSFSRAENLKIHIRSHSGEKPYKCSFEGCQKAYSNSSDRFKH-TRTHSMEKPYMCKVAGCQ 262
              |.|::||.||||.|:|||:|||||.|..|||.||:||:|||.|| .||||.||||:||:.||.
Zfish   557 EGCSKAYSRLENLKTHLRSHTGEKPYVCEHEGCNKAFSNASDRAKHQNRTHSNEKPYVCKIPGCT 621

  Fly   263 KRYTDPSSLRKHVKTF--------------------------------KHSIHLIASQ------- 288
            |||||||||||||||.                                |...|..:.|
Zfish   622 KRYTDPSSLRKHVKTVHGPEAHVTKKQRGETYPRPPPQPREPGATTDQKEYTHATSKQDECLQVK 686

  Fly   289 ------PLTLPSVP-----CLLEASSESAFTCLPAASSVESTSSSSSARYYDDSNNEPSDYSLK- 341
                  |:|..|.|     |..:.|............:|.|...:......:|..||..|...:
Zfish   687 SIKTEKPMTSQSSPGSQSSCSSDQSINGPHVSQGVQLTVNSIGLAGEVAMLEDMENEEEDEENRE 751

  Fly   342 -PKQDAEFSPS 351
             .|:||....|
Zfish   752 GEKEDAPIMDS 762

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
sug	NP_610826.1	C2H2 Zn finger	170..190	CDD:275368	8/19 (42%)
		COG5048	192..>271	CDD:227381	54/81 (67%)
		C2H2 Zn finger	198..218	CDD:275368	11/21 (52%)
		C2H2 Zn finger	226..248	CDD:275368	14/22 (64%)
		C2H2 Zn finger	256..277	CDD:275368	17/20 (85%)
gli3	NP_991291.1	FOXP-CC	488..>522	CDD:465036	10/35 (29%)
		C2H2 Zn finger	524..546	CDD:275368	8/21 (38%)
		SFP1	<548..638	CDD:227516	62/89 (70%)
		C2H2 Zn finger	554..576	CDD:275368	11/21 (52%)
		C2H2 Zn finger	584..607	CDD:275368	14/22 (64%)
		C2H2 Zn finger	615..636	CDD:275368	17/20 (85%)