Protein Alignment sug and zic5

DIOPT Version :10

• Sequence 1: NP_610826.1
• Gene: sug / 36424
• FlyBaseID: FBgn0033782
• Length: 384
• Species: Drosophila melanogaster
• Sequence 2: NP_991290.1
• Gene: zic5 / 403041
• ZFINID: ZDB-GENE-040622-1
• Length: 497
• Species: Danio rerio
• Alignment Length: 412
• Identity: 114/412 - (27%)
• Similarity: 170/412 - (41%)
• Gaps: 115/412 - (27%)

  Fly    11 SGPHSRGIYEPPLGYF--TPYNTPPYIAAYSDSGSWLADHHQH---------------------- 51
            |.||..|::..|.|.:  ......|..:...:..:..|.||.|
Zfish   139 SSPHHHGMFISPTGAYGHAEGGAHPLFSGLHEQAAPGAHHHHHALNGQMRLGLPGDIYGRPEHFG 203

  Fly    52 HQQQH------QQHQQQMQHIRFPTPPITPPRPIAGYGYRQRTQSVIMKARGQQDELCRSPVEFP 110
            |:.:|      ..:.....::...|.|         :|           |.|......|.|::
Zfish   204 HRPEHYGSSSLHSYNSMNLNVNLATAP---------HG-----------ATGAFLRYMRQPIK-- 246

  Fly   111 DDSKSCSSSSECGTASDFVCNWTD--------CDRVFDTLDALAQHVTQRHAIASLTDGLYYCRW 167
                           .:.:|.|.|        |.:.|.|:..|..|||..| :.......:.|.|
Zfish   247 ---------------QELICKWIDQEQTAKKPCSKTFSTMHELVNHVTVEH-VGGPEQSTHVCFW 295

  Fly   168 RGCQRSERGFNARYKMLVHTRTHTKEKPHRCHL--CEKSFSRAENLKIHIRSHSGEKPYKCSFEG 230
            ..|.|..:.|.|:||::.|.|.||.|||..|..  |.|.|:|:||||||.|:|:||||:||.|:|
Zfish   296 EECPREGKAFKAKYKLINHIRVHTGEKPFPCPFPGCGKVFARSENLKIHKRTHTGEKPFKCEFDG 360

  Fly   231 CQKAYSNSSDRFKHTRTHSMEKPYMCKVAGCQKRYTDPSSLRKHVKTFKHSIHLIASQPLTLPSV 295
            |.:.::|||||.||:..|:.:|||.|||.||.|.||.|||||||:|     :|..:..|   ||
Zfish   361 CDRKFANSSDRKKHSHVHTSDKPYFCKVRGCDKSYTHPSSLRKHMK-----VHCKSPPP---PS- 416

  Fly   296 PCLLEASSESAFTCLPAASSV-ESTSSSSSARYYDDSNNEPSDYSLK----------------PK 343
                 |::.|::.  |::::: ::.|.:........||..|...:|.                |.
Zfish   417 -----ANTGSSYH--PSSTTIGDALSPNLDPHRNRSSNLSPQVTNLNEWYVCQGSAGPNNLHTPS 474

  Fly   344 QDAEFSPSYWLGDRQHSYLHSE 365
            .|...|.|    |.:.|:.|::
Zfish   475 SDVPTSES----DDEDSFRHTD 492

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
sug	NP_610826.1	C2H2 Zn finger	170..190	CDD:275368	8/19 (42%)
		COG5048	192..>271	CDD:227381	46/80 (58%)
		C2H2 Zn finger	198..218	CDD:275368	12/21 (57%)
		C2H2 Zn finger	226..248	CDD:275368	11/21 (52%)
		C2H2 Zn finger	256..277	CDD:275368	15/20 (75%)
zic5	NP_991290.1	zf_ZIC	243..286	CDD:436441	12/60 (20%)
		COG5048	297..>489	CDD:227381	80/211 (38%)
		C2H2 Zn finger	298..318	CDD:275368	8/19 (42%)
		C2H2 Zn finger	326..348	CDD:275368	12/21 (57%)
		C2H2 Zn finger	356..378	CDD:275368	11/21 (52%)
		C2H2 Zn finger	386..408	CDD:275368	16/26 (62%)