DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment sug and zic3

DIOPT Version :9

Sequence 1:	NP_610826.1	Gene:	sug / 36424	FlyBaseID:	FBgn0033782	Length:	384	Species:	Drosophila melanogaster
Sequence 2:	NP_001001950.1	Gene:	zic3 / 368263	ZFINID:	ZDB-GENE-030708-2	Length:	448	Species:	Danio rerio

Alignment Length:	211	Identity:	87/211 - (41%)
Similarity:	118/211 - (55%)	Gaps:	24/211 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly   130 CNWTD----------CDRVFDTLDALAQHVTQRHAIASLTDGLYYCRWRGCQRSERGFNARYKML 184
            |.|.|          |||.|.|:..:..||:..| :.......:.|.|..|.|..:.|.|:||::
Zfish   233 CKWIDENQMNRPKKTCDRTFSTMHEMVTHVSMEH-VGGPEQSNHVCYWEDCPREGKSFKAKYKLV 296

  Fly   185 VHTRTHTKEKPHRCHL--CEKSFSRAENLKIHIRSHSGEKPYKCSFEGCQKAYSNSSDRFKHTRT 247
            .|.|.||.|||..|..  |.|.|:|:||||||.|:|:||||:||.|:||.:.::|||||.||...
Zfish   297 NHIRVHTGEKPFPCPFPGCGKIFARSENLKIHKRTHTGEKPFKCEFDGCDRRFANSSDRKKHMHV 361

  Fly   248 HSMEKPYMCKVAGCQKRYTDPSSLRKHVKTFKHSIHLIASQPLT-----LPSVPCLLEASSESAF 307
            |:.:|||:|||  |.|.||.|||||||:|.  |......|.|..     ..:.|.|:.|::|..
Zfish   362 HTSDKPYICKV--CDKSYTHPSSLRKHMKV--HESQGSESSPAASSGYESSTPPVLVSANTEDP- 421

  Fly   308 TCLPAASSVESTSSSS 323
            |..| .|:|:::|:.|
Zfish   422 TKTP-TSAVQNSSAHS 436

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
sug	NP_610826.1	C2H2 Zn finger	170..190	CDD:275368	8/19 (42%)
		zf-H2C2_2	183..207	CDD:290200	11/25 (44%)
		COG5048	192..>271	CDD:227381	45/80 (56%)
		C2H2 Zn finger	198..218	CDD:275368	12/21 (57%)
		zf-H2C2_2	210..237	CDD:290200	16/26 (62%)
		C2H2 Zn finger	226..248	CDD:275368	11/21 (52%)
		C2H2 Zn finger	256..277	CDD:275368	14/20 (70%)
zic3	NP_001001950.1	C2H2 Zn finger	282..302	CDD:275368	8/19 (42%)
		zf-H2C2_2	295..321	CDD:290200	11/25 (44%)
		C2H2 Zn finger	310..332	CDD:275368	12/21 (57%)
		zf-H2C2_2	324..351	CDD:290200	16/26 (62%)
		C2H2 Zn finger	340..362	CDD:275368	11/21 (52%)
		zf-H2C2_2	354..379	CDD:290200	14/26 (54%)
		zf-C2H2	368..390	CDD:278523	16/25 (64%)
		C2H2 Zn finger	370..390	CDD:275368	15/23 (65%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X217
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.910