DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment sug and sna

DIOPT Version :9

Sequence 1:	NP_610826.1	Gene:	sug / 36424	FlyBaseID:	FBgn0033782	Length:	384	Species:	Drosophila melanogaster
Sequence 2:	NP_476732.1	Gene:	sna / 34908	FlyBaseID:	FBgn0003448	Length:	390	Species:	Drosophila melanogaster

Alignment Length:	306	Identity:	79/306 - (25%)
Similarity:	130/306 - (42%)	Gaps:	72/306 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly    14 HSRGIYEPPLGYFT-------PYNTPPYIAAYSDSGSWLADHHQHHQQQHQQHQQQMQHIRFPTP 71
            |.||:.....||.|       |:.:...:||..:..|.|...:|.|.            ..||:|
  Fly   102 HMRGLTAGTTGYTTATPTTINPFQSAFVMAAGCNPISALWSSYQPHL------------AAFPSP 154

  Fly    72 PITPPRPIAGYGYRQRTQ-----SVIMKARGQQDELCRSPVEFP------DDSKSCSSSSECGTA 125
            ..:...|.:.|.|:|.|.     |.:......:|...|:.:..|      |::||.||.:...::
  Fly   155 ASSMASPQSVYSYQQMTPPSSPGSDLETGSEPEDLSVRNDIPLPALFHLFDEAKSSSSGASVSSS 219

  Fly   126 SD-----------------------FVCNWTDCDRVFDTLDALAQHVTQRHAIASLTDGLYYC-- 165
            |.                       |.|:  :|.:::.|...|::| .|.|..|:      .|
  Fly   220 SGYSYTPAMSASSASVAANHAKNYRFKCD--ECQKMYSTSMGLSKH-RQFHCPAA------ECNQ 275

  Fly   166 --RWRGCQRSERGFNARYKMLVHTRTHTKEKPHRCHLCEKSFSRAENLKIHIRSHSGEKPYKCSF 228
              :...|:...:.:.....:.:|.||||  .|.:|.:|.|:|||...|:.|||:|:||||::|
  Fly   276 EKKTHSCEECGKLYTTIGALKMHIRTHT--LPCKCPICGKAFSRPWLLQGHIRTHTGEKPFQC-- 336

  Fly   229 EGCQKAYSNSSDRFKHTRTHSMEKPYMCKVAGCQKRYTDPSSLRKH 274
            ..|.:::::.|:...|.:||...|.|.|:|  |.|.::..|.|.||
  Fly   337 PDCPRSFADRSNLRAHQQTHVDVKKYACQV--CHKSFSRMSLLNKH 380

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
sug	NP_610826.1	C2H2 Zn finger	170..190	CDD:275368	3/19 (16%)
		zf-H2C2_2	183..207	CDD:290200	10/23 (43%)
		COG5048	192..>271	CDD:227381	29/78 (37%)
		C2H2 Zn finger	198..218	CDD:275368	10/19 (53%)
		zf-H2C2_2	210..237	CDD:290200	11/26 (42%)
		C2H2 Zn finger	226..248	CDD:275368	4/21 (19%)
		C2H2 Zn finger	256..277	CDD:275368	8/19 (42%)
sna	NP_476732.1	C2H2 Zn finger	308..328	CDD:275368	10/19 (53%)
		zf-H2C2_2	321..344	CDD:290200	11/24 (46%)
		zf-C2H2	334..356	CDD:278523	4/23 (17%)
		C2H2 Zn finger	336..356	CDD:275368	4/21 (19%)
		zf-H2C2_2	348..373	CDD:290200	9/26 (35%)
		C2H2 Zn finger	364..380	CDD:275368	6/17 (35%)
		C2H2 Zn finger	247..267	CDD:275368	6/22 (27%)
		C2H2 Zn finger	282..302	CDD:275368	3/19 (16%)
		zf-C2H2	306..328	CDD:278523	10/21 (48%)
		COG5048	307..>356	CDD:227381	19/50 (38%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	54	1.000	Inparanoid score	I1809
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	1.050