DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment sug and odd

DIOPT Version :9

Sequence 1:	NP_610826.1	Gene:	sug / 36424	FlyBaseID:	FBgn0033782	Length:	384	Species:	Drosophila melanogaster
Sequence 2:	NP_722922.1	Gene:	odd / 33583	FlyBaseID:	FBgn0002985	Length:	392	Species:	Drosophila melanogaster

Alignment Length:	389	Identity:	96/389 - (24%)
Similarity:	149/389 - (38%)	Gaps:	116/389 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly    27 TPYNTP---------PYIAAYSDSGSWLADHHQHHQQQHQQHQQQMQH----------------I 66
            ||.:||         |.|:..:.:......|..|:|||.||.|||.||                .
  Fly    47 TPPHTPTEEPLRRVHPAISEEAVATQLHMRHMAHYQQQQQQQQQQQQHRLWLQMQQQQQQHQAPQ 111

  Fly    67 RFPTPPITPPRPIAGY----GYRQRTQSVIMKARGQQDE--------LCRSPVEFPDDSKSCSSS 119
            ::|..|.....|:|.:    .:..|..::..:.:.||..        ....|...|...:...:.
  Fly   112 QYPVYPTASADPVAVHQQLMNHWIRNAAIYQQQQQQQQHPHHHHHHGHPHHPHPHPHHVRPYPAG 176

  Fly   120 SECGTASDFVCNWTDCDRVFDTLDALAQHVTQRH--AIASLTDG--------------------L 162
                                  |.:|...|..||  |:.:|..|                    .
  Fly   177 ----------------------LHSLHAAVMGRHFGAMPTLKLGGAGGASGVPSGATGSSRPKKQ 219

  Fly   163 YYCRWRGCQRSERGFNARYKMLVHTRTHTKEKPHRCHLCEKSFSRAENLKIHIRSHSGEKPYKCS 227
            :.|::  |.|.   |...|.:|:|.||||.|:|:.|.:|.|:|.|.::|:.|...||.:||:|||
  Fly   220 FICKY--CNRQ---FTKSYNLLIHERTHTDERPYSCDICGKAFRRQDHLRDHRYIHSKDKPFKCS 279

  Fly   228 FEGCQKAYSNSSDRFKHTRTHSMEKPYMCKVAGCQKRYTDPSSLRKHVKTFKHSIH-----LIAS 287
              .|.|.:..|.....|..||..|.|:.|.:  ||:.:...::|:.|:::  ||..     ::.:
  Fly   280 --DCGKGFCQSRTLAVHKVTHLEEGPHKCPI--CQRSFNQRANLKSHLQS--HSEQSTKEVVVTT 338

  Fly   288 QPLTLPSVP--CLLEASSESAFTCLPAASSVESTSSSSSARYYDDSNNEPSDYSLKPKQDAEFS 349
            .|.|..|||  .|.....|:....||.   ::.:|||||              |.|||:...|:
  Fly   339 SPATSHSVPNQALSSPQPENLAQHLPV---LDLSSSSSS--------------SEKPKRMLGFT 385

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
sug	NP_610826.1	C2H2 Zn finger	170..190	CDD:275368	7/19 (37%)
		zf-H2C2_2	183..207	CDD:290200	12/23 (52%)
		COG5048	192..>271	CDD:227381	27/78 (35%)
		C2H2 Zn finger	198..218	CDD:275368	7/19 (37%)
		zf-H2C2_2	210..237	CDD:290200	11/26 (42%)
		C2H2 Zn finger	226..248	CDD:275368	6/21 (29%)
		C2H2 Zn finger	256..277	CDD:275368	5/20 (25%)
odd	NP_722922.1	COG5048	<203..334	CDD:227381	42/141 (30%)
		C2H2 Zn finger	222..242	CDD:275368	8/24 (33%)
		zf-H2C2_2	234..259	CDD:290200	12/24 (50%)
		C2H2 Zn finger	250..270	CDD:275368	7/19 (37%)
		zf-H2C2_2	262..285	CDD:290200	11/24 (46%)
		C2H2 Zn finger	278..298	CDD:275368	6/21 (29%)
		zf-C2H2	304..326	CDD:278523	5/25 (20%)
		C2H2 Zn finger	306..326	CDD:275368	5/23 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	54	1.000	Inparanoid score	I1809
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	1.050