DRSC/TRiP Functional Genomics Resources

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Protein Alignment sug and Zic4

DIOPT Version :9

Sequence 1:NP_610826.1 Gene:sug / 36424 FlyBaseID:FBgn0033782 Length:384 Species:Drosophila melanogaster
Sequence 2:XP_011241021.1 Gene:Zic4 / 22774 MGIID:107201 Length:403 Species:Mus musculus


Alignment Length:323 Identity:106/323 - (32%)
Similarity:147/323 - (45%) Gaps:64/323 - (19%)


- Green bases have known domain annotations that are detailed below.


  Fly    33 PYIAAYSDSGSWLADHHQHHQQQHQQHQQQMQHIRFP------TPPITPPRPIA----------- 80
            |.:||.|:.......|.|..|..|.:....:..:..|      :.|.. |.|:|           
Mouse    89 PQLAASSNPSVLPGLHEQPPQASHSRPLNGLLRLGIPGDMYARSEPFA-PGPMARSDTLATATAL 152

  Fly    81 -GYGYRQRTQSVIM-KARGQQDELCRSPVEFPDDSKSCSSSSECGTASDFVCNW---------TD 134
             |||....|.::.. ...|......|.|::                 .:.:|.|         ..
Mouse   153 HGYGGMNLTMNLTAPHGPGAFFRYMRQPIK-----------------QELICKWLGDDSPMSPRP 200

  Fly   135 CDRVFDTLDALAQHVTQRHAIASLTDGLYYCRWRGCQRSERGFNARYKMLVHTRTHTKEKPHRCH 199
            |.:.|.|:..|..|||..| :.......:.|.|..|.|..:.|.|:||::.|.|.||.|||..|.
Mouse   201 CSKTFSTMHELVTHVTVEH-VGGPEQANHICFWEECPRQGKPFKAKYKLVNHIRVHTGEKPFPCP 264

  Fly   200 L--CEKSFSRAENLKIHIRSHSGEKPYKCSFEGCQKAYSNSSDRFKHTRTHSMEKPYMCKVAGCQ 262
            .  |.|.|:|:||||||.|:|:||||::|.||||::.::|||||.||:..|:.:|||||||.||.
Mouse   265 FPGCGKVFARSENLKIHKRTHTGEKPFRCEFEGCERRFANSSDRKKHSHVHTSDKPYMCKVRGCD 329

  Fly   263 KRYTDPSSLRKHVKTFKHSIHLIASQPLTLPSVPCLLEASSESAFTCLPAASSVESTSSSSSA 325
            |.||.|||||||:|     :|..:..|          .:..:||.|...|:.|:||....|.|
Mouse   330 KCYTHPSSLRKHMK-----VHGRSPPP----------SSGYDSAITSALASPSLESGREPSVA 377

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
sugNP_610826.1 C2H2 Zn finger 170..190 CDD:275368 8/19 (42%)
zf-H2C2_2 183..207 CDD:290200 11/25 (44%)
COG5048 192..>271 CDD:227381 47/80 (59%)
C2H2 Zn finger 198..218 CDD:275368 12/21 (57%)
zf-H2C2_2 210..237 CDD:290200 16/26 (62%)
C2H2 Zn finger 226..248 CDD:275368 12/21 (57%)
C2H2 Zn finger 256..277 CDD:275368 15/20 (75%)
Zic4XP_011241021.1 zf_ZIC 179..223 CDD:375792 11/61 (18%)
COG5048 <200..345 CDD:227381 73/150 (49%)
C2H2 Zn finger 235..255 CDD:275368 8/19 (42%)
C2H2 Zn finger 263..285 CDD:275368 12/21 (57%)
C2H2 Zn finger 293..315 CDD:275368 12/21 (57%)
C2H2 Zn finger 323..345 CDD:275368 16/26 (62%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 1 1.000 - - X217
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
21.910

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