DRSC/TRiP Functional Genomics Resources

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Protein Alignment sug and Zic3

DIOPT Version :9

Sequence 1:NP_610826.1 Gene:sug / 36424 FlyBaseID:FBgn0033782 Length:384 Species:Drosophila melanogaster
Sequence 2:NP_033601.2 Gene:Zic3 / 22773 MGIID:106676 Length:466 Species:Mus musculus


Alignment Length:422 Identity:122/422 - (28%)
Similarity:170/422 - (40%) Gaps:133/422 - (31%)


- Green bases have known domain annotations that are detailed below.


  Fly    36 AAYSDSGSWLAD---HHQHHQQQHQQHQQQM---------------------------------- 63
            :|::..||..|:   ||.||  .|..|..|:                                  
Mouse    72 SAFTPQGSGYANALGHHHHH--HHHHHASQVPTYGGAASAAFNSTRDFLFRQRGSGLSEAASGGG 134

  Fly    64 QHIRF-------------PTPP---ITPPRPIAGYGYRQRT-----QSVIMKARGQ--------- 98
            ||..|             |.||   :.|.....|.|:...|     ..|.:..||:         
Mouse   135 QHGLFAGSASSLHAPAGIPEPPSYLLFPGLHEQGAGHPSPTGHVDNNQVHLGLRGELFGRADPYR 199

  Fly    99 -----QDELCRSPVEFPDDS-----KSCSSSSECGTASDF-----------VCNWTD-------- 134
                 :.:...:..:||:.|     ...:.::..|..:.|           .|.|.:        
Mouse   200 PVASPRTDPYAASAQFPNYSPMNMNMGVNVAAHHGPGAFFRYMRQPIKQELSCKWIEEAQLSRPK 264

  Fly   135 --CDRVFDTLDALAQHVTQRHAIASLTDGLYYCRWRGCQRSERGFNARYKMLVHTRTHTKEKPHR 197
              |||.|.|:..|..|||..| :.......:.|.|..|.|..:.|.|:||::.|.|.||.|||..
Mouse   265 KSCDRTFSTMHELVTHVTMEH-VGGPEQNNHVCYWEECPREGKSFKAKYKLVNHIRVHTGEKPFP 328

  Fly   198 CHL--CEKSFSRAENLKIHIRSHSGEKPYKCSFEGCQKAYSNSSDRFKHTRTHSMEKPYMCKVAG 260
            |..  |.|.|:|:||||||.|:|:||||:||.||||.:.::|||||.||...|:.:|||:|||  
Mouse   329 CPFPGCGKIFARSENLKIHKRTHTGEKPFKCEFEGCDRRFANSSDRKKHMHVHTSDKPYICKV-- 391

  Fly   261 CQKRYTDPSSLRKHVKTFKHSIHLIASQPLTLPSVPCLLEASSESAFTCLPAASS--VESTSSSS 323
            |.|.||.|||||||:|     :|  .||             .|:|:    |||||  ..||..:.
Mouse   392 CDKSYTHPSSLRKHMK-----VH--ESQ-------------GSDSS----PAASSGYESSTPPAI 432

  Fly   324 SARYYDDSNNEPSDYSLKPKQDAEFSPSY--W 353
            ::....|:...||........:....|::  |
Mouse   433 ASANSKDTTKTPSAVQTSTSHNPGLPPNFNEW 464

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
sugNP_610826.1 C2H2 Zn finger 170..190 CDD:275368 8/19 (42%)
zf-H2C2_2 183..207 CDD:290200 11/25 (44%)
COG5048 192..>271 CDD:227381 46/80 (58%)
C2H2 Zn finger 198..218 CDD:275368 12/21 (57%)
zf-H2C2_2 210..237 CDD:290200 17/26 (65%)
C2H2 Zn finger 226..248 CDD:275368 12/21 (57%)
C2H2 Zn finger 256..277 CDD:275368 14/20 (70%)
Zic3NP_033601.2 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 65..103 11/32 (34%)
Nuclear localization signal. /evidence=ECO:0000250 296..321 10/24 (42%)
C2H2 Zn finger 301..321 CDD:275368 8/19 (42%)
SFP1 <323..407 CDD:227516 51/85 (60%)
C2H2 Zn finger 329..351 CDD:275368 12/21 (57%)
Nuclear localization signal. /evidence=ECO:0000250 329..351 12/21 (57%)
C2H2 Zn finger 359..381 CDD:275368 12/21 (57%)
C2H2 Zn finger 389..409 CDD:275368 15/26 (58%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 403..466 21/86 (24%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 1 1.000 - - X217
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
21.910

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