DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment sug and Mtf1

DIOPT Version :9

Sequence 1:NP_610826.1 Gene:sug / 36424 FlyBaseID:FBgn0033782 Length:384 Species:Drosophila melanogaster
Sequence 2:NP_032662.3 Gene:Mtf1 / 17764 MGIID:101786 Length:675 Species:Mus musculus


Alignment Length:325 Identity:87/325 - (26%)
Similarity:125/325 - (38%) Gaps:87/325 - (26%)


- Green bases have known domain annotations that are detailed below.


  Fly    55 QHQQHQQQMQHIRFP-------TPPITP-PRPIAGYGYRQRTQSVIMKARGQQDELCRSPVEFPD 111
            |....|..:|||..|       .|..|| ||.|.|                              
Mouse    85 QEAMSQGYVQHIISPDQIHLTINPGSTPMPRNIEG------------------------------ 119

  Fly   112 DSKSCSSSSEC-----GTASDFVCNWTDCDRVFDTLDALAQHVTQRHAIASLTDGLYYCRWRGCQ 171
              .:.:..|||     .....:.|.:..|.|.:.|...|..|  |:......|   :.|...||.
Mouse   120 --ATLTLQSECPETKRKEVKRYQCTFEGCPRTYSTAGNLRTH--QKTHRGEYT---FVCNQEGCG 177

  Fly   172 RSERGFNARYKMLVHTRTHTKEKPHRCHL--CEKSFSRAENLKIHIRSHSGEKPYKCSFEGCQKA 234
            ::   |...|.:.:|.|.||||||..|.:  |||:|:....||.|.|.|:| |.:.|..:||.|.
Mouse   178 KA---FLTSYSLRIHVRVHTKEKPFECDVQGCEKAFNTLYRLKAHQRLHTG-KTFNCESQGCSKY 238

  Fly   235 YSNSSDRFKHTRTHSMEKPYMCKVAGCQKRYTDPSSLRKHVKTFKHSIHLIASQPLTLPSVPCLL 299
            ::..||..||.|||:.|||:.|...||.|.:.....|:.||:|  |:    ..:|...||..|..
Mouse   239 FTTLSDLRKHIRTHTGEKPFRCDHDGCGKAFAASHHLKTHVRT--HT----GERPFFCPSNGCEK 297

  Fly   300 EASSE--------------SAFTCLPAASSVESTS-----------SSSSARYYDDSNNEPSDYS 339
            ..|::              :|::.||..:..|.|:           |:.|....:.|:.:..|.|
Mouse   298 TFSTQYSLKSHMKGHDNKGTAYSALPQHNGSEDTNHSLYLSELGLLSTDSELQENSSSTQDQDLS 362

  Fly   340  339
            Mouse   363  362

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
sugNP_610826.1 C2H2 Zn finger 170..190 CDD:275368 5/19 (26%)
zf-H2C2_2 183..207 CDD:290200 13/25 (52%)
COG5048 192..>271 CDD:227381 34/80 (43%)
C2H2 Zn finger 198..218 CDD:275368 9/21 (43%)
zf-H2C2_2 210..237 CDD:290200 11/26 (42%)
C2H2 Zn finger 226..248 CDD:275368 9/21 (43%)
C2H2 Zn finger 256..277 CDD:275368 7/20 (35%)
Mtf1NP_032662.3 COG5048 <92..308 CDD:227381 75/262 (29%)
Nuclear localization signal. /evidence=ECO:0000255 132..137 0/4 (0%)
C2H2 Zn finger 141..163 CDD:275368 7/23 (30%)
zf-H2C2_2 155..182 CDD:290200 8/34 (24%)
C2H2 Zn finger 171..193 CDD:275368 7/24 (29%)
zf-H2C2_2 185..212 CDD:290200 13/26 (50%)
C2H2 Zn finger 201..223 CDD:275368 9/21 (43%)
C2H2 Zn finger 235..252 CDD:275368 7/16 (44%)
zf-H2C2_2 244..270 CDD:290200 13/25 (52%)
C2H2 Zn finger 260..282 CDD:275368 8/23 (35%)
zf-H2C2_2 274..301 CDD:290200 9/32 (28%)
C2H2 Zn finger 290..312 CDD:275368 4/21 (19%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 427..464
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 645..675
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.910

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