DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment sug and tra-1

DIOPT Version :9

Sequence 1:	NP_610826.1	Gene:	sug / 36424	FlyBaseID:	FBgn0033782	Length:	384	Species:	Drosophila melanogaster
Sequence 2:	NP_001022880.2	Gene:	tra-1 / 176548	WormBaseID:	WBGene00006604	Length:	1110	Species:	Caenorhabditis elegans

Alignment Length:	296	Identity:	107/296 - (36%)
Similarity:	143/296 - (48%)	Gaps:	57/296 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly    89 QSVIMKARGQQDELCRSPVEFPDDSKSCSSSSECGTASDFV------CNWTDCDRVFDTLDALAQ 147
            |:|.:...|::  :.|.|..|.....:.::||..|..||.:      |.|..|:..|.||.||..
Worm   165 QNVRLTINGKR--VGRPPGTFKRPQNNAANSSNSGNDSDMMGDHDLTCRWKSCNSSFQTLKALVD 227

  Fly   148 HVTQRHAIASLTD-GLYYCRWRGCQRSERGFNARYKMLVHTRTHTKEKPHRCHL--CEKSFSRAE 209
            ||.:.|..::..: ..:.|.|.||.|:|. |.|.|.::||.|.||.|||::|..  |.|.:||.|
Worm   228 HVQESHVQSTEQEHHAWRCEWEGCDRNET-FKALYMLIVHVRRHTGEKPNKCEYPGCGKEYSRLE 291

  Fly   210 NLKIHIRSHSGEKPYKCSFEGCQKAYSNSSDRFKH-TRTHSMEKPYMCKVAGCQKRYTDPSSLRK 273
            |||.|.|:|:|||||||.|..|:||:||:|||.|| .||||..|||.|::..|.|.|||||||||
Worm   292 NLKTHRRTHTGEKPYKCEFADCEKAFSNASDRAKHQNRTHSNLKPYSCQIPQCTKSYTDPSSLRK 356

  Fly   274 HVKTFKHSIHLIASQPLTLPSVPCLLEASSESAFTCLPAASSVESTSSSSSARYYDDSNNEPSDY 338
            |:|    ::|                            .....|....|..|.|   ||....|:
Worm   357 HIK----AVH----------------------------GDDEYEKAKKSRPANY---SNRRRPDH 386

  Fly   339 SLKPKQDAEFSPSYWLGDRQ-------HSYLHSEDF 367
            .|.|...|...|  :|....       ||.:|.::|
Worm   387 RLAPPTGAMSHP--YLATPNSGASVVAHSSVHQQNF 420

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
sug	NP_610826.1	C2H2 Zn finger	170..190	CDD:275368	9/19 (47%)
		zf-H2C2_2	183..207	CDD:290200	11/25 (44%)
		COG5048	192..>271	CDD:227381	48/81 (59%)
		C2H2 Zn finger	198..218	CDD:275368	11/21 (52%)
		zf-H2C2_2	210..237	CDD:290200	17/26 (65%)
		C2H2 Zn finger	226..248	CDD:275368	13/22 (59%)
		C2H2 Zn finger	256..277	CDD:275368	13/20 (65%)
tra-1	NP_001022880.2	COG5048	<177..358	CDD:227381	85/181 (47%)
		C2H2 Zn finger	246..270	CDD:275368	12/24 (50%)
		SFP1	<272..362	CDD:227516	54/93 (58%)
		C2H2 Zn finger	278..300	CDD:275368	11/21 (52%)
		zf-H2C2_2	292..319	CDD:316026	17/26 (65%)
		C2H2 Zn finger	308..331	CDD:275368	13/22 (59%)
		C2H2 Zn finger	339..362	CDD:275368	14/26 (54%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	48	1.000	Domainoid score	I8021
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.910