Protein Alignment sug and Gli3

DIOPT Version :10

• Sequence 1: NP_610826.1
• Gene: sug / 36424
• FlyBaseID: FBgn0033782
• Length: 384
• Species: Drosophila melanogaster
• Sequence 2: NP_536330.2
• Gene: Gli3 / 140588
• RGDID: 620272
• Length: 1582
• Species: Rattus norvegicus
• Alignment Length: 279
• Identity: 108/279 - (38%)
• Similarity: 137/279 - (49%)
• Gaps: 56/279 - (20%)

  Fly    49 HQHHQQQHQQ--------HQQQMQHIRFPTPPITPPRPIAGY-----------GYRQRTQSVIMK 94
            |.|.|...:|        |...:.|   |.|.....|||.|.           |..:.:||....
  Rat   358 HMHQQILSRQQSLGSAFGHSPPLIH---PAPTFPTQRPIPGIPTVLNPVQVSSGPSESSQSKPTS 419

  Fly    95 ----------------------------ARGQQDELCRSPVEFPDDSKSCSSSSECGTASDFVCN 131
                                        :||||::...:.:...:..|. .|..|.....:..|:
  Rat   420 ESAVSSTGDPMHNKRSKIKPDEDLPSPGSRGQQEQPEGTTLVKEEGDKD-ESKQEPEVIYETNCH 483

  Fly   132 WTDCDRVFDTLDALAQHVTQRHAIASLTDGLYYCRWRGCQRSERGFNARYKMLVHTRTHTKEKPH 196
            |..|.|.|||.|.|..|:...|......:  :.|||..|.|.::.|.|:|.::||.|.||.||||
  Rat   484 WEGCTREFDTQDQLVHHINNDHIHGEKKE--FVCRWLDCSREQKPFKAQYMLVVHMRRHTGEKPH 546

  Fly   197 RCHL--CEKSFSRAENLKIHIRSHSGEKPYKCSFEGCQKAYSNSSDRFKH-TRTHSMEKPYMCKV 258
            :|..  |.|::||.||||.|:|||:|||||.|..|||.||:||:|||.|| .||||.||||:||:
  Rat   547 KCTFEGCTKAYSRLENLKTHLRSHTGEKPYVCEHEGCNKAFSNASDRAKHQNRTHSNEKPYVCKI 611

  Fly   259 AGCQKRYTDPSSLRKHVKT 277
            .||.|||||||||||||||
  Rat   612 PGCTKRYTDPSSLRKHVKT 630

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
sug	NP_610826.1	C2H2 Zn finger	170..190	CDD:275368	8/19 (42%)
		COG5048	192..>271	CDD:227381	54/81 (67%)
		C2H2 Zn finger	198..218	CDD:275368	11/21 (52%)
		C2H2 Zn finger	226..248	CDD:275368	14/22 (64%)
		C2H2 Zn finger	256..277	CDD:275368	17/20 (85%)
Gli3	NP_536330.2	SFP1	<542..632	CDD:227516	62/89 (70%)
		C2H2 Zn finger	548..570	CDD:275368	11/21 (52%)
		C2H2 Zn finger	578..601	CDD:275368	14/22 (64%)
		C2H2 Zn finger	609..630	CDD:275368	17/20 (85%)