DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment sug and glis2b

DIOPT Version :9

Sequence 1:	NP_610826.1	Gene:	sug / 36424	FlyBaseID:	FBgn0033782	Length:	384	Species:	Drosophila melanogaster
Sequence 2:	NP_001276814.1	Gene:	glis2b / 102725539	ZFINID:	ZDB-GENE-091204-120	Length:	489	Species:	Danio rerio

Alignment Length:	173	Identity:	101/173 - (58%)
Similarity:	116/173 - (67%)	Gaps:	4/173 - (2%)

- Green bases have known domain annotations that are detailed below.

  Fly   110 PDDSKSCSSSSECGTASDFVCNWTDCDRVFDTLDALAQHVTQRHAIASLTDGLYYCRWRGCQRSE 174
            |.|::   :|.:........|.|..|..:||:|..|..||...| :....|..|.|.|.||.|..
Zfish   147 PKDTR---ASPDLSADEQLACRWRKCHLLFDSLQDLVDHVNDFH-VKPEKDSGYCCHWEGCARKG 207

  Fly   175 RGFNARYKMLVHTRTHTKEKPHRCHLCEKSFSRAENLKIHIRSHSGEKPYKCSFEGCQKAYSNSS 239
            ||||||||||:|.||||.||||||..|.|||||.||||||.|||:|||||.|.:|||.|.|||||
Zfish   208 RGFNARYKMLIHIRTHTNEKPHRCPTCNKSFSRLENLKIHNRSHTGEKPYICPYEGCNKRYSNSS 272

  Fly   240 DRFKHTRTHSMEKPYMCKVAGCQKRYTDPSSLRKHVKTFKHSI 282
            |||||||||.::|||.||:.||.||||||||||||:|...|.:
Zfish   273 DRFKHTRTHYVDKPYYCKMVGCLKRYTDPSSLRKHIKAHGHFV 315

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
sug	NP_610826.1	C2H2 Zn finger	170..190	CDD:275368	14/19 (74%)
		zf-H2C2_2	183..207	CDD:290200	17/23 (74%)
		COG5048	192..>271	CDD:227381	59/78 (76%)
		C2H2 Zn finger	198..218	CDD:275368	14/19 (74%)
		zf-H2C2_2	210..237	CDD:290200	19/26 (73%)
		C2H2 Zn finger	226..248	CDD:275368	17/21 (81%)
		C2H2 Zn finger	256..277	CDD:275368	16/20 (80%)
glis2b	NP_001276814.1	C2H2 Zn finger	207..223	CDD:275368	12/15 (80%)
		zf-H2C2_2	219..240	CDD:290200	15/20 (75%)
		COG5048	227..>304	CDD:227381	58/76 (76%)
		C2H2 Zn finger	231..251	CDD:275368	14/19 (74%)
		zf-H2C2_2	243..270	CDD:290200	19/26 (73%)
		C2H2 Zn finger	259..281	CDD:275368	17/21 (81%)
		C2H2 Zn finger	289..311	CDD:275368	17/21 (81%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170594659
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0006993
OrthoInspector	1	1.000	-	-		otm25770
orthoMCL	1	0.900	-	-		OOG6_109933
Panther	1	1.100	-	-	LDO	PTHR19818
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X217
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	7	6.840