DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment sug and glis2

DIOPT Version :9

Sequence 1:	NP_610826.1	Gene:	sug / 36424	FlyBaseID:	FBgn0033782	Length:	384	Species:	Drosophila melanogaster
Sequence 2:	XP_002932507.2	Gene:	glis2 / 100492770	XenbaseID:	XB-GENE-12564475	Length:	493	Species:	Xenopus tropicalis

Alignment Length:	247	Identity:	116/247 - (46%)
Similarity:	133/247 - (53%)	Gaps:	40/247 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly   106 PVEFPDDSKSCSSSSECGTASDFVCNWTDCDRVFDTLDALAQHVTQRHAIASLTDGLYYCRWRGC 170
            |..|....|....|.|.......||.|..|:|:|:.|..|..||...| :....|..|.|.|.||
Frog   137 PSMFMSPPKEKRLSLEYTEQKQLVCQWAKCNRLFELLQELVDHVNDFH-VKPEKDAGYCCHWEGC 200

  Fly   171 QRSERGFNARYKMLVHTRTHTKEKPHRCHLCEKSFSRAENLKIHIRSHSGEKPYKCSFEGCQKAY 235
            .|..||||||||||:|.||||.|:||.|..|.|||||.||||||.|||:|||||.|.:|||.|.|
Frog   201 ARRGRGFNARYKMLIHIRTHTNERPHCCPTCHKSFSRLENLKIHNRSHTGEKPYMCPYEGCNKRY 265

  Fly   236 SNSSDRFKHTRTHSMEKPYMCKVAGCQKRYTDPSSLRKHVKTFKH----------SIH------- 283
            |||||||||||||.::|||.||:.|||||||||||||||:|...|          .||
Frog   266 SNSSDRFKHTRTHYVDKPYYCKMPGCQKRYTDPSSLRKHIKAHGHFISHQQRQLLKIHQPPKLPV 330

  Fly   284 -------------------LIASQPLTLPSVPCLLEASSESAFTCLPAASSV 316
                               :..||.|.:|..|..|:.||   ..|...||::
Frog   331 TGDSSYTNGTQLIIPNPAAIFGSQSLPIPLTPGPLDLSS---LACSGMASAL 379

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
sug	NP_610826.1	C2H2 Zn finger	170..190	CDD:275368	14/19 (74%)
		zf-H2C2_2	183..207	CDD:290200	15/23 (65%)
		COG5048	192..>271	CDD:227381	58/78 (74%)
		C2H2 Zn finger	198..218	CDD:275368	14/19 (74%)
		zf-H2C2_2	210..237	CDD:290200	19/26 (73%)
		C2H2 Zn finger	226..248	CDD:275368	17/21 (81%)
		C2H2 Zn finger	256..277	CDD:275368	17/20 (85%)
glis2	XP_002932507.2	C2H2 Zn finger	204..220	CDD:275368	12/15 (80%)
		COG5048	224..>301	CDD:227381	57/76 (75%)
		C2H2 Zn finger	228..248	CDD:275368	14/19 (74%)
		C2H2 Zn finger	256..278	CDD:275368	17/21 (81%)
		C2H2 Zn finger	286..308	CDD:275368	18/21 (86%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0006993
OrthoInspector	1	1.000	-	-		oto104861
Panther	1	1.100	-	-	LDO	PTHR19818
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X217
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	5.010