Protein Alignment vg and VGLL3

DIOPT Version :9

• Sequence 1: NP_523723.1
• Gene: vg / 36421
• FlyBaseID: FBgn0003975
• Length: 453
• Species: Drosophila melanogaster
• Sequence 2: NP_057290.2
• Gene: VGLL3 / 389136
• HGNCID: 24327
• Length: 326
• Species: Homo sapiens
• Alignment Length: 256
• Identity: 74/256 - (28%)
• Similarity: 99/256 - (38%)
• Gaps: 91/256 - (35%)

  Fly   280 QAQYLSASCVVFTNYSGDTASQVDEHFSRALNYN---------NKDS-------KESSSPMSNRN 328
            :.:||::.||:||.:.||..|.|||||||||...         :|..       ::||:..|.||
Human    80 EMEYLNSRCVLFTYFQGDIGSVVDEHFSRALGQAITLHPESAISKSKMGLTPLWRDSSALSSQRN 144

  Fly   329 -FPPSFWNSNYVHPIPAP----TH--HQVSDLYGT--ATDTGYATDPWVPHAAHY---------- 374
             ||.|||.|:| .|.|||    .|  .||:...||  |.|    ..||..|..|.
Human   145 SFPTSFWTSSY-QPPPAPCLGGVHPDFQVTGPPGTFSAAD----PSPWPGHNLHQTGPAPPPAVS 204

  Fly   375 ------------GSYAHA---------AHAHAAHAHAYHHNM----------AQYGSLLRLPQQY 408
                        .||:|.         .|||..|.|.:||:.          ..||.|| :|
Human   205 ESWPYPLTSQVSPSYSHMHDVYMRHHHPHAHMHHRHRHHHHHHHPPAGSALDPSYGPLL-MP--- 265

  Fly   409 ASHGSRLHHDQ----QTAHALEYSSYPTMAG-------LEAQVA-----QVQESSKDLYWF 453
            :.|.:|:...|    :|......|:....||       :...|.     |.|:.||:..|:
Human   266 SVHAARIPAPQCDITKTEPTTVTSATSAWAGAFHGTVDIVPSVGFDTGLQHQDKSKESPWY 326

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
vg	NP_523723.1	Vg_Tdu	282..312	CDD:284876	18/29 (62%)
VGLL3	NP_057290.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	57..80		74/256 (29%)
		Vg_Tdu	82..112	CDD:369418	18/29 (62%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	175..203		8/31 (26%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	233..256		7/22 (32%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165159114
Domainoid	1	1.000	43	1.000	Domainoid score	I12374
eggNOG	1	0.900	-	-		E1_2C0NA
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1146285at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm41435
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	LDO	PTHR15950
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R7863
SonicParanoid	1	1.000	-	-		X2352
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	9	8.930