DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment vg and cfap70

DIOPT Version :9

Sequence 1:	NP_523723.1	Gene:	vg / 36421	FlyBaseID:	FBgn0003975	Length:	453	Species:	Drosophila melanogaster
Sequence 2:	XP_002940644.2	Gene:	cfap70 / 100379775	XenbaseID:	XB-GENE-994711	Length:	1113	Species:	Xenopus tropicalis

Alignment Length:	111	Identity:	29/111 - (26%)
Similarity:	38/111 - (34%)	Gaps:	14/111 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    88 AVAANQASSSGGIGG----GGLGGLGGLGGGPASGLLGSNVVPGSSSVGSVGLGMSPVLSGAAGH 148
            |||.:.|..:||...    |.....|.|..|...|  .....|.|....|..:.:|  |||....
Frog   783 AVALSWAKPAGGTNSKSALGNASEKGTLSKGATEG--PHETTPASHRAESPSVNIS--LSGRPAE 843

  Fly   149 SLHS-SHRTHAHSLAHAHTHPHSHTHTHTHQTKEEDLIVPRSEAEA 193
            ...| :.|....||....|...:|....|..:.|     |.::.||
Frog   844 EKASLTRRASVSSLRSKSTKAGTHKEVTTRASSE-----PEAQPEA 884

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
vg	NP_523723.1	Vg_Tdu	282..312	CDD:284876
cfap70	XP_002940644.2	TPR repeat	643..670	CDD:276809
		TPR repeat	679..704	CDD:276809
		PEP_TPR_lipo	<683..1023	CDD:274350	29/111 (26%)
		TPR repeat	709..739	CDD:276809
		TPR repeat	744..770	CDD:276809
		TPR	<900..1089	CDD:223533
		TPR repeat	954..984	CDD:276809
		TPR repeat	992..1020	CDD:276809
		TPR repeat	1026..1050	CDD:276809
		TPR repeat	1059..1083	CDD:276809
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	44	1.000	Domainoid score	I12086
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	122	1.000	Inparanoid score	I4594
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm48647
Panther	1	1.100	-	-	LDO	PTHR15950
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R7863
SonicParanoid	1	1.000	-	-		X2352
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	6	6.180