Protein Alignment AspRS and DPS1

DIOPT Version :10

• Sequence 1: NP_476609.1
• Gene: AspRS / 36420
• FlyBaseID: FBgn0002069
• Length: 531
• Species: Drosophila melanogaster
• Sequence 2: NP_013083.1
• Gene: DPS1 / 850643
• SGDID: S000003941
• Length: 557
• Species: Saccharomyces cerevisiae
• Alignment Length: 552
• Identity: 293/552 - (53%)
• Similarity: 367/552 - (66%)
• Gaps: 27/552 - (4%)

  Fly     2 VEDKEQVA------NGEQVSKKGAKKLAKAAKKAEQKAENASTAAANNAGGD---SAEDHAAGRY 57
            ||:..:.|      :|:.:|||..|||.|..:|..:|.|.|....|.....:   :|||.|...|
Yeast    11 VEESAEPAQVILGEDGKPLSKKALKKLQKEQEKQRKKEERALQLEAEREAREKKAAAEDTAKDNY 75

  Fly    58 GLSEMIQSKDKRSER------NFVPVSELSGQVGKGLVWVRGRVHTSRAKGKQ-CFLILRQQSST 115
            |...:|||:|  |:|      .||.:.|......:  |..|.|||.:|.:|.. .||.||||:|.
Yeast    76 GKLPLIQSRD--SDRTGQKRVKFVDLDEAKDSDKE--VLFRARVHNTRQQGATLAFLTLRQQASL 136

  Fly   116 VQCILAVG--DVISKQMVKFAGNIPKESIIDIQAKPVAVSSKIESCTEQSLELSVEQIFVISQAK 178
            :|.::...  ..|||.|||:||::..|||:.::.....|...|:|.|.|:||:.:.:|:.||:..
Yeast   137 IQGLVKANKEGTISKNMVKWAGSLNLESIVLVRGIVKKVDEPIKSATVQNLEIHITKIYTISETP 201

  Fly   179 AQLPLQIEDASRPENADDAEGLNIRVNQDTRLDNRVLDLRTPANQAIFRLEAGVCRLFRDILTEQ 243
            ..||:.:|||||.|...:|.||.: ||.|||||.||:||||..||||||::||||.|||:.|..:
Yeast   202 EALPILLEDASRSEAEAEAAGLPV-VNLDTRLDYRVIDLRTVTNQAIFRIQAGVCELFREYLATK 265

  Fly   244 GFTEIHTPKIISAASEGGANVFTVSYFKDSAYLAQSPQLYKQMAIAADFDKVYTVGAVFRAEDSN 308
            .|||:||||::.|.||||::||.|:|||..||||||||..||..|.|||::||.:|.|||||:||
Yeast   266 KFTEVHTPKLLGAPSEGGSSVFEVTYFKGKAYLAQSPQFNKQQLIVADFERVYEIGPVFRAENSN 330

  Fly   309 THRHLTEFVGLDLEMAFKYHYHEVLHTIGNTFTSIFKGLRDKYAKEIESVGQQYKVDAFKFLEPP 373
            ||||:|||.|||:||||:.||||||.|:...|..||..|..::|.|||.|.:||.|:.||..:..
Yeast   331 THRHMTEFTGLDMEMAFEEHYHEVLDTLSELFVFIFSELPKRFAHEIELVRKQYPVEEFKLPKDG 395

  Fly   374 LI--LQFADGVAMLREAGVETGDEEDLSTPNEKLLGRLVKAKYDTDFYILDKFPLAIRPFYTMPD 436
            .:  |.:.:|:.|||.||.|.||.|||||.|||.||:||:.||||||||||||||.|||||||||
Yeast   396 KMVRLTYKEGIEMLRAAGKEIGDFEDLSTENEKFLGKLVRDKYDTDFYILDKFPLEIRPFYTMPD 460

  Fly   437 PNNPVYSNSYDMFMRGEEILSGAQRIHDPEYLIERAKHHGI--DTSKIAAYIESFRYGCPPHAGG 499
            |.||.||||||.||||||||||||||||...|.||.|.||:  :...:..|.:.|.|||||||||
Yeast   461 PANPKYSNSYDFFMRGEEILSGAQRIHDHALLQERMKAHGLSPEDPGLKDYCDGFSYGCPPHAGG 525

  Fly   500 GIGMERVVMLYLGLDNIRKTSMFPRDPKRLTP 531
            |||:|||||.||.|.|||:.|:||||||||.|
Yeast   526 GIGLERVVMFYLDLKNIRRASLFPRDPKRLRP 557

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
AspRS	NP_476609.1	PLN02850	49..531	CDD:215456	276/494 (56%)
DPS1	NP_013083.1	PLN02850	19..557	CDD:215456	289/542 (53%)