DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment AspRS and AT4G26870

DIOPT Version :9

Sequence 1:	NP_001260930.1	Gene:	AspRS / 36420	FlyBaseID:	FBgn0002069	Length:	531	Species:	Drosophila melanogaster
Sequence 2:	NP_194417.2	Gene:	AT4G26870 / 828794	AraportID:	AT4G26870	Length:	532	Species:	Arabidopsis thaliana

Alignment Length:	534	Identity:	249/534 - (46%)
Similarity:	348/534 - (65%)	Gaps:	25/534 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly    11 GEQVSKKGAKKLAKAAKKAEQKAENASTAAANNAGGDSAEDHAAGRYG------LSEMIQSKDKR 69
            ||::|||.:||.|...:|..:|.|. ..|.:::...:..::..:..||      |...::.|:
plant    11 GEKISKKESKKRAAKLEKLLRKQER-EEATSSSLSLEEEDESCSSNYGDVTTNELQSAVEGKE-- 72

  Fly    70 SERNFVPVSELSGQVGKGLVWVRGRVHTSRAKGKQCFLILRQQSSTVQCILAVGDVISKQMVKFA 134
                ...||.|..::....|.:|||:|.:|..|.:.|:|||:...||||::....| ...|:||.
plant    73 ----LTDVSNLVEEIVGSEVSIRGRLHKNRLVGTKLFVILRESGFTVQCVVEETRV-GANMIKFV 132

  Fly   135 GNIPKESIIDIQAKPVAVSS---KIESCTEQSLELSVEQIFVISQAKAQLPLQIEDASRPENADD 196
            ..:.:||::::    :.|.|   |..:.|.|.:|:.|.:::.:|::...|||.:|||:|.|:..:
plant   133 KQLSRESVVEL----IGVVSHPKKPLTGTTQQVEIHVRKMYCLSRSLPNLPLVVEDAARSESDIE 193

  Fly   197 AEGLN----IRVNQDTRLDNRVLDLRTPANQAIFRLEAGVCRLFRDILTEQGFTEIHTPKIISAA 257
            ..|.:    .||.|||||:|||||:||||||||||::..|...||:.|..:||.||||||:|:.:
plant   194 KSGKDGKQAARVLQDTRLNNRVLDIRTPANQAIFRIQCQVQIAFREYLQSKGFLEIHTPKLIAGS 258

  Fly   258 SEGGANVFTVSYFKDSAYLAQSPQLYKQMAIAADFDKVYTVGAVFRAEDSNTHRHLTEFVGLDLE 322
            ||||:.||.:.|....|.|||||||:|||||..|..:|:.||.|||||||.|||||.||||||:|
plant   259 SEGGSAVFRLDYKGQPACLAQSPQLHKQMAICGDMRRVFEVGPVFRAEDSFTHRHLCEFVGLDVE 323

  Fly   323 MAFKYHYHEVLHTIGNTFTSIFKGLRDKYAKEIESVGQQYKVDAFKFLEPPLILQFADGVAMLRE 387
            |..:.||.|::..:|..|..||..:.::..||:|||.:||...:.|||...|.|.||:|:.||:|
plant   324 MEIRMHYSEIMDLVGELFPFIFTKIEERCPKELESVRKQYPFQSLKFLPQTLRLTFAEGIQMLKE 388

  Fly   388 AGVETGDEEDLSTPNEKLLGRLVKAKYDTDFYILDKFPLAIRPFYTMPDPNNPVYSNSYDMFMRG 452
            ||.|.....||:|.:|:.||:||..||.|:||:|.::|.|:|||||||..|:..||||:|:|:||
plant   389 AGEEVDPLGDLNTESERKLGQLVLEKYKTEFYMLHRYPSAVRPFYTMPYENDSNYSNSFDVFIRG 453

  Fly   453 EEILSGAQRIHDPEYLIERAKHHGIDTSKIAAYIESFRYGCPPHAGGGIGMERVVMLYLGLDNIR 517
            |||:||||||||||.|.:||:..|||...|:.||::||||.|||.|.|:|:||||||...|:|||
plant   454 EEIMSGAQRIHDPELLEKRARECGIDVKTISTYIDAFRYGAPPHGGFGVGLERVVMLLCALNNIR 518

  Fly   518 KTSMFPRDPKRLTP 531
            |||:||||.:||||
plant   519 KTSLFPRDSQRLTP 532

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
AspRS	NP_001260930.1	PLN02850	49..531	CDD:215456	235/494 (48%)
		AspRS_cyto_N	89..187	CDD:239815	32/100 (32%)
		AsxRS_core	203..527	CDD:238399	188/323 (58%)
AT4G26870	NP_194417.2	PLN02850	2..532	CDD:215456	247/532 (46%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	375	1.000	Domainoid score	I171
eggNOG	1	0.900	-	-		E1_COG0017
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H1032
Inparanoid	1	1.050	460	1.000	Inparanoid score	I371
OMA	1	1.010	-	-		QHG60941
OrthoDB	1	1.010	-	-		D677307at2759
OrthoFinder	1	1.000	-	-		FOG0004194
OrthoInspector	1	1.000	-	-		otm2454
orthoMCL	1	0.900	-	-		OOG6_100778
Panther	1	1.100	-	-	O	PTHR43450
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X2940
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	15	14.840