Protein Alignment AspRS and Nars

DIOPT Version :9

• Sequence 1: NP_001260930.1
• Gene: AspRS / 36420
• FlyBaseID: FBgn0002069
• Length: 531
• Species: Drosophila melanogaster
• Sequence 2: NP_001363950.1
• Gene: Nars / 70223
• MGIID: 1917473
• Length: 549
• Species: Mus musculus
• Alignment Length: 562
• Identity: 148/562 - (26%)
• Similarity: 241/562 - (42%)
• Gaps: 97/562 - (17%)

  Fly     5 KEQVANGEQVSKKGAKKLAKAAKKAEQKAENASTAAANNAGGDSAEDHAAGRYGLSE----MIQS 65
            ||.....:.:||...|.:.|...:.:.|.::...        ..|||:......|.|    :|::
Mouse    50 KENEVGWDVISKSQMKNIKKMWHREQMKNDSREK--------KEAEDNLRREKNLEEAKKIIIKN 106

  Fly    66 KDKRSERNFVPVSELSGQVGKGLVWVRGRVHTSRAKGKQ-CFLILRQQSSTVQCILA-------V 122
            .....|...|.:|.|.|..|: .|.|.|.||..|.:||. .||:||..:..:||:|:       .
Mouse   107 DPSLPEPACVKISALEGYRGQ-RVKVFGWVHRLRRQGKNLMFLVLRDGTGYLQCVLSDDLCQCYN 170

  Fly   123 GDVISKQMVKFAGNIPKESIIDIQAKPVAVSSKIESCTEQSL-----ELSVEQIFVISQAKAQLP 182
            |.|:|.:                  ..|||...:....:...     |||.:...::..|.|
Mouse   171 GVVLSTE------------------SSVAVYGTLNLTPKGKQAPGGHELSCDFWELVGLAPA--- 214

  Fly   183 LQIEDASRPENADDAEGLNIRVNQDTRLDNRVLDLRTPANQAIFRLEAGVCRLFRDILTEQGFTE 247
                     ..||:.  :|...:.|.:|:||.:.:|......|.:..:.:.|.|||...::|:.|
Mouse   215 ---------GGADNL--INEESDVDVQLNNRHMMIRGENMSKILKARSMITRCFRDHFFDRGYCE 268

  Fly   248 IHTPKIISAASEGGANVFTVSYFKDSAYLAQSPQLYKQMAIAADFDKVYTVGAVFRAEDSNTHRH 312
            :.||.::....||||.:|.:.||.:.|:|.||.|||.:..:.|..| |:.:...:|||.|.|.||
Mouse   269 VTTPTLVQTQVEGGATLFKLDYFGEEAFLTQSSQLYLETCLPALGD-VFCIAQSYRAEQSRTRRH 332

  Fly   313 LTEFVGLDLEMAFKYHYHEVLHTIGNTFTSIFKGLRDKYAKEIESVGQQ------YKVDA-FKFL 370
            |.||..::.|..|.            ||..:...|.|.....::.|.:.      |:::. ||
Mouse   333 LAEFTHVEAECPFL------------TFEDLLNRLEDLVCDVVDRVLKSPVASIVYELNPNFK-- 383

  Fly   371 EPP----LILQFADGVAMLREAGVETGD------EEDLSTPNEKLLGRLVKAKYDTDFYILDKFP 425
             ||    ..:.::|.:..|:|..|:..|      .:|:....|:|:...:     .:..:|.:||
Mouse   384 -PPKRPFRRMNYSDAIEWLKEHDVKKEDGTFYEFGDDIPEAPERLMTDTI-----NEPILLCRFP 442

  Fly   426 LAIRPFYTMPDPNNPVYSNSYDMFMRG-EEILSGAQRIHDPEYLIERAKHHGIDTSKIAAYIESF 489
            :.|:.||....|.:|..:.|.|:.|.. .||:.|:.|..|.|.::|..|..|||.:....|.:..
Mouse   443 VEIKSFYMQRCPEDPRLTESVDVLMPNVGEIVGGSMRSWDSEEILEGYKREGIDPAPYYWYTDQR 507

  Fly   490 RYGCPPHAGGGIGMERVVMLYLGLDNIRKTSMFPRDPKRLTP 531
            :||..||.|.|:|:||.:...|...:||...::||..:|..|
Mouse   508 KYGTCPHGGYGLGLERFLSWILNRYHIRDVCLYPRFLQRCRP 549

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
AspRS	NP_001260930.1	PLN02850	49..531	CDD:215456	140/516 (27%)
		AspRS_cyto_N	89..187	CDD:239815	26/110 (24%)
		AsxRS_core	203..527	CDD:238399	98/341 (29%)
Nars	NP_001363950.1	AsnS	126..549	CDD:223096	129/476 (27%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0017
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810