Protein Alignment AspRS and Nars1

DIOPT Version :10

• Sequence 1: NP_476609.1
• Gene: AspRS / 36420
• FlyBaseID: FBgn0002069
• Length: 531
• Species: Drosophila melanogaster
• Sequence 2: NP_001385496.1
• Gene: Nars1 / 291556
• RGDID: 1307238
• Length: 559
• Species: Rattus norvegicus
• Alignment Length: 562
• Identity: 147/562 - (26%)
• Similarity: 244/562 - (43%)
• Gaps: 91/562 - (16%)

  Fly     2 VEDKEQVANGEQVSKKGAKKLAKAAKKAEQKAENASTAAANNAGGDSAEDHAAGRYGLSE----M 62
            |:.:::....:.:||...|.:.|...:.:.|:::...        ..|||:......|.|    :
  Rat    57 VDSQKENERWDVISKSQMKNIKKMWHREQMKSDSREK--------KEAEDNLRREKNLEEAKKII 113

  Fly    63 IQSKDKRSERNFVPVSELSGQVGKGLVWVRGRVHTSRAKGKQ-CFLILRQQSSTVQCILA----- 121
            |::.....|...|.:|.|.|..|: .|.|.|.||..|.:||. .||:||..:..:||:|:
  Rat   114 IKNDPSLPEPACVKISALEGYRGQ-RVKVFGWVHRLRRQGKNLMFLVLRDGTGYLQCVLSDDLCQ 177

  Fly   122 --VGDVISKQMVKFAGNIPKESIIDIQAKPVAVSSKIESCTEQSL-----ELSVEQIFVISQAKA 179
              .|.|:|.:                  ..|||...:....:...     |||.:...::..|.|
  Rat   178 CYNGVVLSTE------------------SSVAVYGTLNLTPKGKQAPGGHELSCDFWELVGLAPA 224

  Fly   180 QLPLQIEDASRPENADDAEGLNIRVNQDTRLDNRVLDLRTPANQAIFRLEAGVCRLFRDILTEQG 244
                        ..||:.  :|...:.|.:|:||.:.:|......|.:..:.:.|.|||...::|
  Rat   225 ------------GGADNL--INEESDVDVQLNNRHMMIRGENMSKILKARSMITRCFRDHFFDRG 275

  Fly   245 FTEIHTPKIISAASEGGANVFTVSYFKDSAYLAQSPQLYKQMAIAADFDKVYTVGAVFRAEDSNT 309
            :.|:.||.::....||||.:|.:.||.:.|:|.||.|||.:..:.|..| |:.:...:|||.|.|
  Rat   276 YCEVTTPTLVQTQVEGGATLFKLDYFGEEAFLTQSSQLYLETCLPALGD-VFCIAQSYRAEQSRT 339

  Fly   310 HRHLTEFVGLDLEMAFKYHYHEVLHTIGNTFTSIFKGLRDKYAKEIESVGQQ------YKVDA-F 367
            .|||.||..::.|..|.            ||..:...|.|.....::.|.:.      |.::. |
  Rat   340 RRHLAEFTHVEAECPFL------------TFEDLLSRLEDLVCDVVDRVLKSPVASIVYDLNPNF 392

  Fly   368 KFLEPPL-ILQFADGVAMLREAGVETGD------EEDLSTPNEKLLGRLVKAKYDTDFYILDKFP 425
            |..:.|. .:.::|.:..|||..|:..|      .:|:....|:|:...:     .:..:|.:||
  Rat   393 KAPKRPFRRMNYSDAIEWLREHDVKKEDGTFYEFGDDIPEAPERLMTDTI-----NEPILLCRFP 452

  Fly   426 LAIRPFYTMPDPNNPVYSNSYDMFMRG-EEILSGAQRIHDPEYLIERAKHHGIDTSKIAAYIESF 489
            :.|:.||....|.:|..:.|.|:.|.. .||:.|:.|..|.|.::|..|..|||.:....|.:..
  Rat   453 VEIKSFYMQRCPEDPRLTESVDVLMPNVGEIVGGSMRSWDSEEILEGYKREGIDPAPYYWYTDQR 517

  Fly   490 RYGCPPHAGGGIGMERVVMLYLGLDNIRKTSMFPRDPKRLTP 531
            :||..||.|.|:|:||.:...|...:||...::||..:|..|
  Rat   518 KYGTCPHGGYGLGLERFLSWILNRYHIRDVCLYPRFLQRCRP 559

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
AspRS	NP_476609.1	PLN02850	49..531	CDD:215456	140/513 (27%)
Nars1	NP_001385496.1	AsnRS_cyto_like_N	138..220	CDD:239818	24/99 (24%)
		AsxRS_core	236..555	CDD:238399	98/336 (29%)