Protein Alignment AspRS and Dars1

DIOPT Version :10

• Sequence 1: NP_476609.1
• Gene: AspRS / 36420
• FlyBaseID: FBgn0002069
• Length: 531
• Species: Drosophila melanogaster
• Sequence 2: NP_803228.2
• Gene: Dars1 / 226414
• MGIID: 2442544
• Length: 501
• Species: Mus musculus
• Alignment Length: 507
• Identity: 337/507 - (66%)
• Similarity: 405/507 - (79%)
• Gaps: 11/507 - (2%)

  Fly    25 AAKKAEQKAENASTAAANNAGGDSAEDHAAGRYGLSEMIQSKDKRSERNFVPVSELSGQVGKGLV 89
            |::|.::|.....         |:|||:|..|||:|.||||::| .:|..|.|.:|:.|....:|
Mouse     6 ASRKGQEKPREIV---------DAAEDYAKERYGISSMIQSQEK-PDRVLVRVKDLTVQKADDVV 60

  Fly    90 WVRGRVHTSRAKGKQCFLILRQQSSTVQCILAVGDVISKQMVKFAGNIPKESIIDIQAKPVAVSS 154
            |||.||||||||||||||:||||...||.::||||..||||||||.||.||||||::.....|:.
Mouse    61 WVRARVHTSRAKGKQCFLVLRQQQFNVQALVAVGDHASKQMVKFAANINKESIIDVEGVVRKVNQ 125

  Fly   155 KIESCTEQSLELSVEQIFVISQAKAQLPLQIEDASRPENADDAEGLNIRVNQDTRLDNRVLDLRT 219
            ||.|||:|.:||.|::|:|||.|:.:||||::||.|||...:.:| ...|||||||||||:||||
Mouse   126 KIGSCTQQDVELHVQKIYVISLAEPRLPLQLDDAIRPEVEGEEDG-RATVNQDTRLDNRVIDLRT 189

  Fly   220 PANQAIFRLEAGVCRLFRDILTEQGFTEIHTPKIISAASEGGANVFTVSYFKDSAYLAQSPQLYK 284
            ..:||||||::|:|.|||:.|..:||.||.||||||||||||||||||||||::|||||||||||
Mouse   190 STSQAIFRLQSGICHLFRETLINKGFVEIQTPKIISAASEGGANVFTVSYFKNNAYLAQSPQLYK 254

  Fly   285 QMAIAADFDKVYTVGAVFRAEDSNTHRHLTEFVGLDLEMAFKYHYHEVLHTIGNTFTSIFKGLRD 349
            ||.|.|||:||:.:|.||||||||||||||||||||:||||.||||||:..|.:|...|||||::
Mouse   255 QMCICADFEKVFCIGPVFRAEDSNTHRHLTEFVGLDIEMAFNYHYHEVVEEIADTLVQIFKGLQE 319

  Fly   350 KYAKEIESVGQQYKVDAFKFLEPPLILQFADGVAMLREAGVETGDEEDLSTPNEKLLGRLVKAKY 414
            ::..||::|.:|:..:.||||||.|.|::.:.:|||||||||..||||||||||||||||||.||
Mouse   320 RFQTEIQTVSKQFPCEPFKFLEPTLRLEYCEALAMLREAGVEMDDEEDLSTPNEKLLGRLVKEKY 384

  Fly   415 DTDFYILDKFPLAIRPFYTMPDPNNPVYSNSYDMFMRGEEILSGAQRIHDPEYLIERAKHHGIDT 479
            |||||:|||:|||:|||||||||.||..|||||||||||||||||||||||:.|.|||.|||||.
Mouse   385 DTDFYVLDKYPLAVRPFYTMPDPRNPKQSNSYDMFMRGEEILSGAQRIHDPQLLTERALHHGIDL 449

  Fly   480 SKIAAYIESFRYGCPPHAGGGIGMERVVMLYLGLDNIRKTSMFPRDPKRLTP 531
            .||.|||:|||:|.|||||||||:|||.||:|||.|:|:|||||||||||||
Mouse   450 EKIKAYIDSFRFGAPPHAGGGIGLERVTMLFLGLHNVRQTSMFPRDPKRLTP 501

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
AspRS	NP_476609.1	PLN02850	49..531	CDD:215456	331/481 (69%)
Dars1	NP_803228.2	PLN02850	20..501	CDD:215456	331/482 (69%)
		Aspartate. /evidence=ECO:0000250	251..254		2/2 (100%)