Protein Alignment AspRS and dars-1

DIOPT Version :10

• Sequence 1: NP_476609.1
• Gene: AspRS / 36420
• FlyBaseID: FBgn0002069
• Length: 531
• Species: Drosophila melanogaster
• Sequence 2: NP_499089.1
• Gene: dars-1 / 176334
• WormBaseID: WBGene00001094
• Length: 531
• Species: Caenorhabditis elegans
• Alignment Length: 533
• Identity: 326/533 - (61%)
• Similarity: 398/533 - (74%)
• Gaps: 16/533 - (3%)

  Fly     9 ANGEQ--VSKKGAKKLAKAAKKAE---QKAENASTAAANNAGGDSAEDHAAGRYGLSEMIQSKDK 68
            |.|||  :|||...|||:.|||.|   :|..|...|||.:     .||.:...||...::.||:|
 Worm     5 AEGEQPKLSKKELNKLARKAKKDEKAGEKGGNQQQAAAMD-----QEDASKDFYGSYGLVNSKEK 64

  Fly    69 RSERNFVPVSELSGQVGKGLVWVRGRVHTSRAKGKQCFLILRQQSSTVQCILAVGDVISKQMVKF 133
            : ..||:.|.|::.......||||||:||:|:|||.|||:|||...|||..:.:.:.|||||:||
 Worm    65 K-VLNFLKVKEINVSNATKDVWVRGRIHTTRSKGKNCFLVLRQGVYTVQVAMFMNEKISKQMLKF 128

  Fly   134 AGNIPKESIIDIQAKPVAVSSKIESCTEQSLELSVEQIFVISQAKAQLPLQIEDASR-----PEN 193
            ..:|.||||:|:.|....|.:.|||||::.:||..:|:||:|.:..:||||||||||     .|.
 Worm   129 VSSISKESIVDVYATINKVDNPIESCTQKDVELLAQQVFVVSTSAPKLPLQIEDASRRAPTDEEK 193

  Fly   194 ADDAEGLNIRVNQDTRLDNRVLDLRTPANQAIFRLEAGVCRLFRDILTEQGFTEIHTPKIISAAS 258
            |.:.|.....||.||||||||:|||||.:.||||::||:|..||:||..:||.||..||||||.|
 Worm   194 ASEQENQLAVVNLDTRLDNRVIDLRTPTSHAIFRIQAGICNQFRNILDVRGFVEIMAPKIISAPS 258

  Fly   259 EGGANVFTVSYFKDSAYLAQSPQLYKQMAIAADFDKVYTVGAVFRAEDSNTHRHLTEFVGLDLEM 323
            |||||||.|||||.|||||||||||||||||.||:||||:|.||||||||||||:||||||||||
 Worm   259 EGGANVFEVSYFKGSAYLAQSPQLYKQMAIAGDFEKVYTIGPVFRAEDSNTHRHMTEFVGLDLEM 323

  Fly   324 AFKYHYHEVLHTIGNTFTSIFKGLRDKYAKEIESVGQQYKVDAFKFLEPPLILQFADGVAMLREA 388
            ||.:|||||:.||....|.:||||:..|..||.:||.||..:.|:|.||||||::.|.:.:|||.
 Worm   324 AFNFHYHEVMETIAEVLTQMFKGLQQNYQDEIAAVGNQYPAEPFQFCEPPLILKYPDAITLLREN 388

  Fly   389 GVETGDEEDLSTPNEKLLGRLVKAKYDTDFYILDKFPLAIRPFYTMPDPNNPVYSNSYDMFMRGE 453
            |:|.|||:|||||.||.||:|||.||.||||:||||||::||||||||.::..||||||||||||
 Worm   389 GIEIGDEDDLSTPVEKFLGKLVKEKYSTDFYVLDKFPLSVRPFYTMPDAHDERYSNSYDMFMRGE 453

  Fly   454 EILSGAQRIHDPEYLIERAKHHGIDTSKIAAYIESFRYGCPPHAGGGIGMERVVMLYLGLDNIRK 518
            |||||||||||.:.|:||||||.:|.:||.:||:||:||||||||||||:|||.||:|||.|||.
 Worm   454 EILSGAQRIHDADMLVERAKHHQVDLAKIQSYIDSFKYGCPPHAGGGIGLERVTMLFLGLHNIRL 518

  Fly   519 TSMFPRDPKRLTP 531
            .|:||||||||||
 Worm   519 ASLFPRDPKRLTP 531

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
AspRS	NP_476609.1	PLN02850	49..531	CDD:215456	305/486 (63%)
dars-1	NP_499089.1	PLN02850	4..531	CDD:215456	324/531 (61%)