DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Nmda1 and Faim2

DIOPT Version :9

Sequence 1:	NP_523722.1	Gene:	Nmda1 / 36419	FlyBaseID:	FBgn0013305	Length:	324	Species:	Drosophila melanogaster
Sequence 2:	NP_082500.2	Gene:	Faim2 / 72393	MGIID:	1919643	Length:	317	Species:	Mus musculus

Alignment Length:	311	Identity:	117/311 - (37%)
Similarity:	173/311 - (55%)	Gaps:	14/311 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly    25 NPPQGGYGGYPPQGGYPPQGP--PQGYPPY--AQGGAQPYPQPYGQGPPPGGYAPQPGFIQPPPS 85
            |...|..|......|.....|  |...|.|  |..|.......:.|||......|...::.|..|
Mouse    10 NKAPGTEGQQHQANGEKKDAPAVPSAPPSYEEATSGEGLKAGTFPQGPTAVPLHPSWAYVDPSGS 74

  Fly    86 AGGYGAYDDPESQPKN---FSFDDQSIRRGFIRKVYLILMGQLIVTFGAVALFVYHEGTKTFARN 147
            :|..|.:  |....::   ||:|||.:||.||||||.||:.||:||...||||.:.:..|.:.:.
Mouse    75 SGYEGGF--PAGHHEHFTTFSWDDQKVRRLFIRKVYTILLVQLLVTLAVVALFTFCDVVKDYVQA 137

  Fly   148 NMWLFWVALGVMLVTMLSMACCESVRRQTPTNFIFLGLFTAAQSFLMGVSATKYAPKEVLMAVGI 212
            |...:|.:..|...|.|::|||...||..|.|.|.|.:||.:.::|.|:.::.|....||:.:.|
Mouse   138 NPGWYWASYAVFFATYLTLACCSGPRRHFPWNLILLTIFTLSMAYLTGMLSSYYNTTSVLLCLVI 202

  Fly   213 TAAVCLALTIFALQTKYDFTMMGGILIACMVVFLIFG-IVAIFVKGKIIT---LVYASIGALLFS 273
            ||.|||::|||:.|||:|||...|:|...::.....| ::|:.:..:.:.   .|||.:||.:|:
Mouse   203 TALVCLSVTIFSFQTKFDFTSCQGVLFVLLMTLFFSGLLLAVLLPFQYVPWLHAVYAVLGAGVFT 267

  Fly   274 VYLIYDTQLMMGGEHKYSISPEEYIFAALNLYLDIINIFMYILTIIGASRD 324
            ::|.:||||:| |..::|:|||||||.|||:|||||.||.:.|.:.|.:|:
Mouse   268 LFLAFDTQLLM-GNRRHSLSPEEYIFGALNIYLDIIYIFTFFLQLFGTNRE 317

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Nmda1	NP_523722.1	LFG_like	103..320	CDD:198410	95/220 (43%)
Faim2	NP_082500.2	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..54		10/43 (23%)
Faim2	NP_082500.2	LFG_like	93..313	CDD:198410	95/220 (43%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0670
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG57711
OrthoDB	1	1.010	-	-		D1290306at2759
OrthoFinder	1	1.000	-	-		FOG0000200
OrthoInspector	1	1.000	-	-		mtm8676
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R158
SonicParanoid	1	1.000	-	-		X332
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	9	8.860