Protein Alignment Nmda1 and TMBIM1

DIOPT Version :10

• Sequence 1: NP_523722.1
• Gene: Nmda1 / 36419
• FlyBaseID: FBgn0013305
• Length: 324
• Species: Drosophila melanogaster
• Sequence 2: NP_071435.2
• Gene: TMBIM1 / 64114
• HGNCID: 23410
• Length: 311
• Species: Homo sapiens
• Alignment Length: 338
• Identity: 131/338 - (38%)
• Similarity: 184/338 - (54%)
• Gaps: 48/338 - (14%)

  Fly     1 MSWQSVPQYPQYQDPNQQYNYGGGNPPQGGY-------GGYPPQGGYPP--QGPPQGYPPYAQGG 56
            ||..|.|  |.|:|.|..|   .|.||.|||       ||||...|||.  .|.|.|||
Human     1 MSNPSAP--PPYEDRNPLY---PGPPPPGGYGQPSVLPGGYPAYPGYPQPGYGHPAGYP------ 54

  Fly    57 AQPYPQPYGQGPPPGGYAPQPGFIQPPPSAGGYGAYDDPESQPKNFSF-----DDQSIRRGFIRK 116
             ||.|..:   |.|..|.|..|:              |.|.:..:.||     ||:.:|..||||
Human    55 -QPMPPTH---PMPMNYGPGHGY--------------DGEERAVSDSFGPGEWDDRKVRHTFIRK 101

  Fly   117 VYLILMGQLIVTFGAVALFVYHEGTKTFARNNMWLFWVALGVMLVTMLSMACCESVRRQTPTNFI 181
            ||.|:..||::|...:|:|.:.|....|.|.|:.:::|:..|.:||.|.:|||:..||:.|.|.|
Human   102 VYSIISVQLLITVAIIAIFTFVEPVSAFVRRNVAVYYVSYAVFVVTYLILACCQGPRRRFPWNII 166

  Fly   182 FLGLFTAAQSFLMGVSATKYAPKEVLMAVGITAAVCLALTIFALQTKYDFTMMGGILIACMVVFL 246
            .|.|||.|..|:.|..::.|..|.|::|:.|||.|.:::|||..|||.|||...|:.....:|.|
Human   167 LLTLFTFAMGFMTGTISSMYQTKAVIIAMIITAVVSISVTIFCFQTKVDFTSCTGLFCVLGIVLL 231

  Fly   247 IFGIVA----IFVKGKIITLVYASIGALLFSVYLIYDTQLMMGGEHKYSISPEEYIFAALNLYLD 307
            :.|||.    .|.....:.::||::||:.|:::|.|||||:: |..|::||||:||..||.:|.|
Human   232 VTGIVTSIVLYFQYVYWLHMLYAALGAICFTLFLAYDTQLVL-GNRKHTISPEDYITGALQIYTD 295

  Fly   308 IINIFMYILTIIG 320
            ||.||.::|.::|
Human   296 IIYIFTFVLQLMG 308

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nmda1	NP_523722.1	LFG_like	103..320	CDD:198410	93/225 (41%)
TMBIM1	NP_071435.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..37		17/40 (43%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	50..72		11/31 (35%)
		LFG_like	89..308	CDD:198410	91/219 (42%)